Publicaciones en Señales Biomedicas

Publications of Biomedical Signal Interpretation & Computational Simulation (BSICoS)* Group.

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* Former, before 2014, Communications Technology Group (GTC): Biomedical signal applications

13th ESGCO MEETING OCTOBER 23rd - 25th ZARAGOZA 2024 www.esgco2024.i3a.es

2024

Journals and Book

J Lázaro, N. Reljin, R. Bailón, E. Gil, Y. Noh, P. Laguna, K. H. Chon (2024) Tracking Tidal Volume from Holter and Wearable Armband Electrocardiogram Monitoring, IEEE Journal of Biomedical and Health Informatics, vol. xx, n. x, doi:10.1109/JBHI.2024.3383232
A. Hernando, M. D. Peláez-Coca, E. Gil (2024) Decomposing photoplethysmogram waveforms into systolic and diastolic waves, with application to hyperbaric environments, Biomedical Signal Processing and Control, pp. xxx doi: 10.1016/j.bspc.2023.104814
P. B. Munroe, N. Aung, J. Ramírez (2024) Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size, News & views, Nature genetics, doi:10.1038/s41588-023-01650-1
R. M. Rosales, K. A. Mountris, A. Oliván-Viguera, M. Pérez-Zabalza, G. Cedillo-Servin, O. Iglesias-García, A. Hrynevich, M. Castilho, J. Malda, F. Prósper, M. Doblaré, M. M. Mazo, E. Pueyo (2024) Experimentally-guided in silico design of engineered heart tissues to improve cardiac electrical function after myocardial infarction, Computers in Biology and Medicin, 171, 108044. doi: 10.1016/j.compbiomed.2024.108044
G. D. Costa, C. Nos, A. Zabalza, M. Buron, M. Magyari, F. Sellebjerg, A. I. Guerrero, L. Roselli, M. L. La Porta, M. Martinis, R. Bailon, S. Kontaxis, E. Laporta, E. Garcia, F. B Pokorny, B. W Schuller, A. Folarin, C. Stewart, L. Leocani, S. Vairavan, N. Cummins, R. Dobson, M. Hotopf, V. Narayan, X. Montalban, P. S.Sorensen, and G. Comi,on behalf of the RADAR-CNS consortium (2024) A wearable device perspective on the standard definitions of disability progression in multiple sclerosis Multiple, Sclerosis Journal Volume 30, Issue 1
https://doi.org/10.1177/13524585231214362
P. Armañac‐Julián, A. Martín‐Montero,| J. Lázaro, R. Hornero, P. Laguna, L. Kheirandish‐Gozal, D. Gozal, E. Gil, R. Bailón, G. Gutiérrez‐Tobal (2024) Persistent sleep‐disordered breathing independently contributes to metabolic syndrome in prepubertal children, Pediatr Pulmonol. vol. 59, pp.111–120, DOI: 10.1002/ppul.26720
N. Laita, R. M. Rosales, M. Wu, P. Claus, S. Janssens, M.A. Martínez, M. Doblare, E. Peña (2024) On modeling the in vivo ventricular passive mechanical behavior from in vitro experimental properties in porcine hearts, Computers and Structures 292 107241 doi:10.1016/j.compstruc.2023.107241
M.D. Peláez, A. Hernando, M.T. Lozano, J. Bolea, D. Izquierdo, C. Sánchez (2024). Heart Rate Variability to Automatically Identify Hyperbaric States Considering Respiratory Component. Sensors 2024, 24(2), 447; https://doi.org/10.3390/s24020447
Sgambato, B. G. M.H Hasbani, D. Y Barsakcioglu, J. Ibáñez, A. Jakob, M. Fournelle, M.-X. Tang, D. Farina (2024) High Performance Wearable Ultrasound as a Human-Machine Interface for wrist and hand kinematic tracking. IEEE Trans. Biomed. Eng. 1–10, : doi 10.1109/TBME.2023.3307952
L. Sörnmo, R. Bailon, P. Laguna (2024). Spectral Analysis of Heart Rate Variability in Time-Varying Conditions and in the Presence of Confounding Factors. IEEE Reviews in Biomedical Engineering. vol. 17, pp. 322-341, doi: 10.1109/RBME.2022.3220636.
Lubel, E., Rohlén, R., Sgambato, B. G., Barsakcioglu, D. Y., Ibáñez, J., Tang, M.-X., & Farina, D. (2024). Accurate Identification of Motoneuron Discharges from Ultrasound Images Across the Full Muscle Cross-Section. IEEE Transactions on Biomedical Engineering, 39(3), 1–12. https://doi.org/10.1109/TBME.2023.3340019
Hietakoste, S., Armañac-Julián, P., Karhu, T., Bailón, R., Sillanmäki, S., Töyräs, J., Leppanen, T., Myllymaa, S. & Kainulainen, S. (2024). Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia. IEEE Transactions on Biomedical Engineering, vol. 71, n. 1, doi: 10.1109/TBME.2023.3300079.
C. Celotto, C. Sánchez, M. Abdollahpur, F. Sandberg, J. F. Rodríguez, P. Laguna and E. Pueyo (2024) The Frequency of Atrial Fibrillatory Waves is Modulated by the Spatiotemporal Pattern of Acetylcholine Release: a 3D Computational Study. Front. Physiol. 14:1189464. doi: 10.3389/fphys.2023.1189464
D. Cajal, E. Gil, P. Laguna, C. Varon, D. Testelmans, B. Buyse, C. Jensen, R. Hoare, R. Bailon, J. Lázaro (2024) Obstructive Sleep Apnea Screening by Joint Saturation Signal Analysis and PPG-derived Pulse Rate Oscillations, IEEE Journal of Biomedical and Health Informatics, vol. 28, n. 1, doi: 10.1109/JBHI.2023.3331947

Conference Proceedings

Ph.D. Thesis

Pablo Armañac (2024) Cardiovascular Signal Processing Oriented to Long-Term Monitoring Zaragoza University.

Patents

2023

Journals and Book

García-Mendívil, M. Pérez-Zabalza, A. Oliver-Gelabert, J.M. Vallejo-Gil, J. Fañanás-Mastral, M. Vázquez-Sancho, J.A. André-Bellido, A.S. Vaca-Núñez, C. Ballester-Cuenca, E.R. Diez, L. Ordovás, E. Pueyo (2023). Interindividual age-independent differences in human CX43 impact ventricular arrhythmic risk. Research, 6, 0254. https://doi-org/10.34133/research.0254
Velarte, A. Otin, P. Giménez-Gómez, X. Muñoz-Berbel, E. Pueyo (2023). Fiber optic-based system for high-resolution monitoring of stretch in excised tissues. Biosensors, 13, 900. https://doi.org/10.3390/bios13100900
A. Mountris, E. Pueyo (2023). Cardiac electrophysiology meshfree modeling through the Mixed Collocation Method. Applied Sciences, 13, 11460. https://doi.org/10.3390/app132011460
García-Mendívil, M. Pérez-Zabalza, S. Duwé, L. Ordovás, E. Pueyo (2023). Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy. Star Protocols, 4, 102730. https://doi.org/10.1016/j.xpro.2023.102730
Aguiló, J., Moussaoui, D., Chon, K., & Bailón, R. (2023). Robust, reliable, and continuous assessment in health: the challenge of wearable and remote technologies. Frontiers in Physiology, 14
Nardelli, M., & Bailón, R. (2023). Advances in Wearable Photoplethysmography Applications in Health Monitoring. Sensors, 23(16), 7064.
Kontaxis, S., Laporta, E., Garcia, E., Martinis, M., Leocani, L., Roselli, L., Buron, M., Guerrero, A.I., Zabala, A., Cummins, N., Vairavan, S., Hotopf, M., Dobson, R., Narayan, V. La Porta, M.L., Dalla Costa, G., Magyari, M., Sorensen, P., Nos, C., Bailón, R., Commi, G.C. & Radar-Cns Consortium. (2023). Automatic Assessment of the 2-Minute Walk Distance for Remote Monitoring of People with Multiple Sclerosis. Sensors, 23(13), 6017.
Cummins, N., Dineley, J., Conde, P., Matcham, F., Siddi, S., Lamers, F., Carr, E., Lavelle, G., Leightley, D., White, K., Oetzman, C., Campbell, E., Simblett, S., Bruce, S., Haro, J.M., Penninx, B., Ranjan, Y., Rashid, Z., Stewart, C., Folarin, A., Bailon, R., Schuller, B., Wykes, T., Vairavan, S., Dobson, R., Narayan, V., Hotpof, M. & RADAR-CNS Consortium. (2023). Multilingual markers of depression in remotely collected speech samples: A preliminary analysis. Journal of affective disorders, 341, 128-136.
S. Duijvenboden, J. Ramírez, M. Orini, N. Aung, S. E. Petersen, A. Doherty, A. Tinker , MD, P. B. Munroe, P. D. Lambiase (2023), Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects. Circulation. 2023;148:00–00. DOI: 10.1161/CIRCULATIONAHA.123.064633
Lubel, E. B. Grandi Sgambato, R. Rohlén, J. Ibáñez , D. Y. Barsakcioglu, M-X Tang, and D. Farina (2023) Non-Linearity in Motor Unit Velocity Twitch Dynamics: Implications for Ultrafast Ultrasound Source Separation. IEEE Trans. Neural Syst. Rehabil. Eng. 31, 3699–3710. doi: r 10.1109/TNSRE.2023.3315146
H. A. Bukhari, C. Sánchez, P. Laguna, M. Potse and E. Pueyo (2023) Differences in ventricular wall composition may explain inter-patient variability in the ECG response to variations in serum potassium and calcium, vol. 14 pp. 1-14; Front. Physiol. - Cardiac Electrophysiology, doi: 10.3389/fphys.2023.1060919
S. van Duijvenboden, J. Ramírez, W. J. Young, K. J. Olczak, F. Ahmed, M. J.A.Y. Alhammadi, C. G. Bell, . P. Morris, P. B. Munroe (2023) International Consortium of Blood Pressure. Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension. The American Journal of Human Genetics 110, 1–17,
N. Gómez-Fonseca, J. Ramírez, J. P. Martínez P. Laguna (2023) Time-Warping Analysis of the T-Wave Peak-to-End Interval to Quantify Ventricular Repolarization Dispersion During Ischemia. IEEE Journal of Biomedical and Health Informatics, vol. 27, n. 11, pp. 5314-5325; doi: 10.1109/JBHI.2023.3310878
F. L. Bueno-Palomeque, K. A. Mountris, N. Ortigosa, R. Bailón, B. Bijnens, F. Crispi, E. Pueyo, A. Mincholé, P. Laguna (2023). QRS-T angles as markers for heart sphericity in subjects with intrauterine growth restriction: a simulation study. IEEE Journal of Biomedical and Health Informatics. vol. 27, n. 10, pp. 4707-4718 doi: 10.1109/JBHI.2023.3297550
Butkuviene M, Petrenas A, Martin-Yebra A, Marozas V, Sornmo L. (2023) Characterization of Atrial Fibrillation Episode Patterns: A Comparative Study. IEEE Trans Biomed Eng. 2023 Jul 7;PP. doi: 10.1109/TBME.2023.3293252. Epub ahead of print. PMID: 37418404.
L. Bachi, H. Halvaei, C. Perez, A. Martín-Yebra, A. Petrenas, A. Solosenko, L. Johnson, V. Marozas, J. P. Martínez, E. Pueyo, M. Stridh, P. Laguna, and L. Sornmo, (2023) ECG Modeling for Simulation of Arrhythmias in Time-Varying Conditions. IEEE Trans Biomed Eng. vol. 70, n. 12, pp. 3449 - 3460, doi: 10.1109/TBME.2023.3288701
Spampinato, D. A., Ibanez, J., Rocchi, L. & Rothwell, J. (2023) Motor potentials evoked by transcranial magnetic stimulation: interpreting a simple measure of a complex system. J. Physiol. 0, 1–25, DOI: 10.1113/JP281885.
C. Sánchez, A. Hernando , J. Bolea, D. Izquierdo, G. Rodríguez, A. Olea, M. T. Lozano, M. D. Peláez-Coca (2023). Enhancing Safety in Hyperbaric Environments through Analysis of Autonomic Nervous System Responses: A Comparison of Dry and Humid Conditions. Sensors. 23, 5289, https://doi.org/10.3390/s23115289
H. Naderi, J. Ramírez, S. van Duijvenboden, E. Ruiz, N. Aung, L. Wang, C. Chahal, K. Lekadir, S. Petersen,P. Munroe (2023) Predicting left ventricular hypertrophy from the 12-lead electrocardiogram in the UK Biobank imaging study using machine learning, European Heart Journal - Digital Health ) 4, 316–324, doi:10.1093/ehjdh/ztad037
Po-Yu Fong, D. Spampinato, K. Michell, M. Mancuso, K. Brown, J. Ibáñez, A. Di Santo, A. Latorre, K. Bhatia, J. C Rothwell, L. Rocchi (2023). EEG responses induced by cerebellar TMS at rest and during visuomotor adaptation. Neuroimage 275, 120188. doi.org/10.1016/j.neuroimage.2023.120188.
S Siddi, R Bailon, I Giné-Vázquez, F Matcham, F Lamers, S Kontaxis, E Laporta, E Garcia, F Lombardini, P Annas, M Hotopf, B W J H Penninx, A Ivan, K M White, S Difrancesco, P Locatelli, J Aguiló, M T Peñarrubia-Maria, V A Narayan, A Folarin, D Leightley, N Cummins, S Vairavan, Y Ranjan, A Rintala, G de Girolamo, S K Simblett, T Wykes; PAB members; I Myin-Germeys, R Dobson, J M Haro; RADAR-CNS consortium (2023) The usability of daytime and night-time heart rate dynamics as digital biomarkers of depression severity. Psychological Medicine, 1-12. doi:10.1017/S0033291723001034
Kontaxis S, Laporta E, Garcia E, Guerrero AI, Zabalza A, Matteo M, Lucia R, Simblett S, Weyer J, Hotopf M, Narayan VA, Rashid Z, Folarin AA, Dobson RJB, Buron MD, Leocani L, Cummins N, Vairavan S, Costa GD, Magyari M, Sørensen PS, Nos C, Bailón R, Comi G , The Radar-Cns Consortium (2023). Autonomic response to walk tests is useful for assessing outcome measures in people with multiple sclerosis. Front Physiol. 2023 Apr 6;14:1145818. doi: 10.3389/fphys.2023.1145818.
C. Pérez, E. Pueyo, J. P. Martínez, J. Viik, P. Laguna, (2023) QT Interval Time Lag in Response to Heart Rate Changes During Stress Test for Coronary Artery Disease Diagnosis, Biomedical Signal Processing and Control, vol. 86, 105056, doi: 10.1016/j.bspc.2023.105056
Peter H. Charlton, et. all. (2023) The 2023 wearable photoplethysmography roadmap. Physiological Measurement. vol. 44, 111001 doi:10.1088/1361-6579/acead2
Lavalle R, Condominas E, Haro JM, Giné-Vázquez I, Bailon R, Laporta E, Garcia E, Kontaxis S, Alacid GR, Lombardini F, Preti A, Peñarrubia-Maria MT, Coromina M, Arranz B, Vilella E, Rubio-Alacid E, RADAR-MDD Spain, Matcham F, Lamers F, Hotopf M, Penninx BWJH, Annas P, Narayan V, Simblett SK, Siddi S, the RADAR-CNS Consortium (2023). The Impact of COVID-19 Lockdown on Adults with Major Depressive Disorder from Catalonia: A Decentralized Longitudinal Study. International Journal of Environmental Research and Public Health. 2023; 20(6):5161. https://doi.org/10.3390/ijerph20065161
J. Saiz-Vivó, V. D. A. Corino, A. Martín-Yebra, L. T. Mainardi, R. Hatala, L. Sörnmo (2023). Atrial fibrillation episode patterns as predictor of clinical outcome of catheter ablation. Med Biol Eng Comput, ) 61:317–327. doi: 10.1007/s11517-022-02713-x
D. Sokas s, E. Tamuleviciute-Prasciene, A. Beigiene, V. Barasaite, J. Marozas, R. Kubilius, R. Bailon, and A. Petrenas (2023) "Wearable-based Assessment of Heart Rate Response to Physical Stressors in Patients After Open-Heart Surgery With Frailty, IEEE Journal of Biomedical and Health Informatics, vol.. 27, n. 4, doi: 10.1109/JBHI.2023.3244005
M. Rinkevičius, P.H. Charlton, R. Bailón, V. Marozas (2023). Influence of Photoplethysmogram Signal Quality on Pulse Arrival Time during Polysomnography. Sensors 2023, 23, 2220. https://doi.org/10.3390/s23042220
D. Farina, E. Burdet, C. Mehring, J. Ibáñez (2023) Roboticists Want to Give You a Third Arm: Neural control for manipulating extra robotic limbs. IEEE Spectrum vol. 60, n. 3
B. Asadi, J. N. Cuenca-Zaldivar, N. N. Ansari, J. Ibáñez, P. Herrero, S. Calvo (2023) Brain Analysis with a Complex Network Approach in Stroke Patients Based on Electroencephalography: A Systematic Review and Meta-Analysis. Healthcare 11, 666 (2023).
C. Celotto, C. Sánchez, K. A. Mountris, P. Laguna, E. Pueyo (2023) Steady-State and Transient Effects of SK Channel Block and Adrenergic Stimulation to Counteract Acetylcholine-Induced Arrhythmogenic Effects in the Human Atria: A Computational Study, Computers in Biology and Medicine, 157, 106719 doi:10.1016/j.compbiomed.2023.106719
W. J. Young, J. Haessler, J. Benjamins, L. Repetto, J. Yao, A. Isaacs, A. R. Harper, J. Ramírez, et. al. (2023). Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease. Nature Communications, | 14:1411, doi:10.1038/s41467-023-36997-w.
A. Loewe, A. Luik, R. Sassi, P. Laguna (2023) Together we are strong! Collaboration between clinicians
and engineers as an enabler for better diagnosis and therapy of atrial arrhythmias, Medical & Biological Engineering & Computing, p. 1-3, doi: 10.1007/s11517-023-02788-0
M. Orini, S. van Duijvenboden, W. J. Young, J. Ramírez, A. R. Jones, A. Tinker, P. B. Munroe, P. D. Lambiase (2023). Premature atrial and ventricular contractions detected on wearable-format ECGs and prediction of cardiovascular events. European Heart Journal – Digital Health, ) 4, 112–118, doi:10.1093/ehjdh/ztad007
A. Greco, G. Valenza, J. Lazaro, J. M. Garzón-Rey, Jordi Aguiló, C. de la Cámara, R. Bailón, E. Pasquale Scilingo (2023) Acute stress state classification based on electrodermal activity modeling. IEEE Transactions on Affective Computing. vol. 14 n. 1 pp. 788-799, doi: 10.1109/TAFFC.2021.3055294,
J. Ibáñez*, B. Zicher, K. E. Brown, L. Rocchi, A. Casolo, A. Del Vecchio, D. Spampinato, C. C. Vollette, J. C. Rothwell, S. N. Baker, D. Farina, (2023), Standard intensities of transcranial alternating current stimulation over the motor cortex do not entrain corticospinal inputs to motor neurons. J. Physiol. 0, 0–1, doi: 10.1113/JP282983.
C. Pérez, R. Cebollada, K. A. Mountris, J. P. Martínez, P. Laguna, E. Pueyo (2023) The Role of β-adrenergic Stimulation in QT Interval Adaptation to Heart Rate During Stress Test, Plos One 18(1): e0280901. doi:10.1371/journal. pone.0280901
N. Garatachea, E. Pueyo, T. Eijsvogels (2022). Prevention of sudden death in sports: a global and multidisciplinary observatory for scientific research and knowledge transfer. Reviews in Cardiovascular Medicine, 24(1), 12. doi:10.31083/j.rcm2401012
E. García-Pagès, A. Arza-Valdes, C. Puig, T. Castro, M. Ottaviano, M. T. Arredondo, M. L. Bernal, R. López-Antón, C. De La Cámara, E. Gil, P. Laguna, R. Bailón, J. Aguiló, J. M. Garzón-Rey (2023) Psychosomatic response to acute emotional stress in healthy students, Front. Physiol. 13:960118, pp 1-21. doi: 10.3389/fphys.2022.960118
A. Martín-Montero; P. Armañac-Julián; E. Gil; L. Kheirandish-Gozal; D. Álvarez; J. Lázaro; R. Bailón; D. Gozal; P. Laguna; R. Hornero; G. C. Gutiérrez-Tobal (2023) Pediatric Sleep Apnea: Characterization of Apneic Events and Sleep Stages Using Heart Rate Variability, Computers in Biology and Medicine, 154, 106549, doi: 10.1016/j.compbiomed.2023.106549.
F. Hug, S. Avrillon, J. Ibáñez, D. Farina, (2023) Common synaptic input, synergies and size principle: Control of spinal motor neurons for movement generation. The Journal of Physiology, 601, 11–20. doi:10.1113/JP283698

Conference Proceedings

J. Lazaro, R. Bailon, E. Gil (2023). Potential of Electrocardiogram-Derived-Respiration based on QRS slopes and R-wave angle for Discriminating Apneic from Non-Apneic Segments. IEEE 19th International Conference on Body Sensor Networks (BSN). Boston MA, USA, pp. 1-4. DOI: 10.1109/BSN58485.2023.10331074
S. Romagnoli, C. Perez, L. Burattini, E. Pueyo, M. Morettini, A. Sbrollini, J. P. Martínez, P. Laguna (2023). Model-based Estimators of QT Series Time Delay in Following Heart-Rate Changes. 45nd Annual International Conference of the IEEE EMBS. Sydney, Australia, pp. 1-4. DOI: 10.1109/EMBC40787.2023.10340130
P. Armañac-Julián, A. Martín-Montero, S. Hietakoste, J. Lazaro, S. Kainulainen, D. Gozal, R. Hornero, P. Laguna, G. C. Gutiérrez-Tobal, E. Gil, R. Bailón (2023), Characterization of Cardiopulmonary Coupling in Pediatric Patients with Obstructive Sleep Apnea. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.245
F L Bueno-Palomeque, K. Mountris, N. Ortigosa, R. Bailón, B. Bijnens, F. Crispi, E. Pueyo, A. Mincholé, P. Laguna (2023), QRS Width and T-peak to T-end Interval Are Prolonged in Preadolescents with Severe Intrauterine Growth Restriction at Birth When Compared to Controls. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.344
N. Gómez-Fonseca, J. Ramírez, A. Martin, M. M. Demidova, P. Platonov, J. P. Martínez, P. Laguna (2023), Changes in T-peak-to-T-end Morphology Measured by Time-Warping Are Associated with Ischemia-Induced Ventricular Fibrillation in a Porcine Model. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.408
C. Celotto, C. Sánchez, M. Abdollahpur, F. Sandberg, P. Laguna, E. Pueyo (2023), Dependence of Atrial Fibrillatory Rate Variations Induced by Head-Up/Down Tilt-Test on Autonomic Action. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.285
C. Pérez, E. Pueyo, J. P. Martínez, L. Sornmo, P. Laguna (2023), Evaluation of a QT Adaptation Time Estimator for ECG Exercise Stress Test in Controlled Simulation. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.235
I. Noguero-Soler, P. Revilla, J. Ramos, E. Pueyo, A. Mincholé (2023), ECG Morphology-Based Markers for Risk Stratification in Hypertrophic Cardiomyopathy. Proceed ings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.293
R. Rosales, K. Mountris, M. Doblaré, M. Mazo, E. Pueyo (2023), In Silico Assessment of Arrhythmic Risk in Infarcted Ventricles Engrafted with Engineered Heart Tissues. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.275
L. Garcia-Mendivil, M. Pérez, R. Rosales, J. M. Vallejo-Gil, J. Fañanás-Mastral, M. Vázquez-Sancho, J. A. Bellido‑Morales, A. S. Vaca‑Núñez, C. Ballester-Cuenca, L. Ordovás, E. Pueyo (2023),Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.352
J. Rodriguez-Carbo, A. Mincholé, E. Pueyo (2023),ECG-based Characterization of the Extent, Severity and Spatial Location of Acute Ischemia in Patients with and without Prior Myocardial Infarction. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.429
C. Sales-Bellés, A. Mincholé, J. Melero, M. Cabrera-Ramos, I. Montilla-Padilla, L. Sorinas, I. Julián, E. Pueyo, J. Ramos (2023),Left Bundle Branch Area Pacing Generates More Physiological Ventricular Activation Sequences than Right Ventricular Pacing. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.316
S. Palacios, R. Smisek, K. Curila, U. C. Nguyen, F. Prinzen, J. Halamek, F. Plesinger, P. Jurak, E. Pueyo, J. P. Martínez (2023),Spatial Dispersion of Activation and Repolarization Times Associated with Different Cardiac Pacing Modes. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.420
A. Rapalis, D. Sokas, V. Pluščiauskaitė, S. Jurgionytė, Ž. Stankevičiūtė, J. Lazaro, A. Savanevičienė, R. Bailón, E. Kaniusas, V. Marozas (2023),Photoplethysmogram Morphology in Stress: From Mental to Pain to Physical Activity-induced Stress. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.055
F. Ferrati, E. Gil, J. Lazaro (2023). Coverage of PPG-based Wearable Devices During Office Tasks. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.206
J. Ramírez, A. Miguel, S. Duijvenboden, M. Orini, W. Young, A. Tinker, P. Lambiase, P. Munroe, J. P. Martínez (2023). A Multi-layer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.342
A. Martin, J. Molinos, J. P. Martínez (2023). Assessment of QT Interval Dynamics Induced by Heart Rate Changes through Bivariate Phase-Rectified Signal Averaging. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.398
M. Orini, S. Duijvenboden, J. Ramírez, W. Young, A. Tinker, P. Munroe, P. Lambiase (2023). Ultra-Short Beat-to-Beat Repolarization Variability Predicts Cardiovascular Events in Individuals without Cardiovascular Disease. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.178
J. Madrid, P. Munroe, S. Duijvenboden, J. Ramírez, A. Mincholé (2023). ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia. Proceedings of the XLIX International Conference on Computing in Cardiology. Atlanta, USA. pp 1-4, DOI: 10.22489/CinC.2023.169
Pérez Martínez, A; López Andres, C; Pastor Oliver, C; Pueyo, E; Oliván Viguera (2023), A. Chronic myocardial infarction attenuates transmural heterogeneities and alters the response to endothelin and β-adrenergic stimulation in porcine ventricles. Cross-Talk of cell in the Heart: Novel Mechanisms of Disease and Arrhythmias meeting, Liverpool, United Kingdom, 2023.
Pérez Martínez, A; Rosales, M; Pastor, C; Oliván Viguera, A; Pueyo, E (2023). Cold storage of cardiac slices better preserve the native characteristics of cardiac tissue than traditional culture methods. 47th EWGCCE Annual meeting of the ESC Working Group on Cardiac Cellular Electrophysiology. Copenhagen, Dennmark, 2023.
Oliván Viguera, A; Pérez Martínez, A; García Mendivil, L; Vaca Nuñez, A. S; Bellido Morales, J. A; Sorribas Berjón, J. F; Matamala Adell, M; Vázquez Sancho, M; Fañanás Mastral, J; Vallejo Gil, J. M; Ballester Cuenca, C; Pueyo, E (2023). Eletrophysiologycal and immunohistological evaluation of SK channels from human ventricles: differential functional expression in valvular disease. 47th EWGCCE Annual meeting of the ESC Working Group on Cardiac Cellular Electrophysiology. Copenhagen, Dennmark, 2023.
C. Sales Bellés, J. Melero, J. Ramos, A. Mincholé, E. Pueyo (2023). Análisis frecuencial del complejo QRS del electrocardiograma para la caracterización de la estimulación con marcapasos. XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023. https://doi.org/10.26754/jjii3a.20239022
E. Garrido Huéscar, l. Vandeweyer, L. García Mendivil, N. Hernández Bellido, E. Pueyo, W. H. de Vos, L. Ordovás (2023). Cardiomiocitos derivados de células pluripotentes inducidas (hiPSC-CM) con progerina inducible para estudiar envejecimiento cardiaco, XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023, https://doi.org/10.26754/jjii3a.20239068
J. Madrid, J. Ramírez, A. Mincholé (2023). ECG-Based Unsupervised Clustering in Coronary Artery Disease Associates with Ventricular Arrhythmia, XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023, https://doi.org/10.26754/jjii3a.20239034
A. Pérez Martínez, E. Pueyo, A. Oliván (2023). Evaluación electrofisiológica e immunohistológica de canales SK en ventrículo humano: expresión funcional en patología valvular, XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023 https://doi.org/10.26754/jjii3a.20239030
N. Gómez Fonseca, J. Ramírez, A. Martín Yebra, P. Platonov, J. P. Martínez, P. Laguna (2023). Los cambios en la morfología del intervalo Tpico-Tfin medidos mediante time-warping se asocian con la fibrilación ventricular inducida por la isquemia en un modelo porcino, XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023, https://doi.org/10.26754/jjii3a.20239065
N. Hernández Bellido, E. Ramos Marquès, A. Hernández Vicente, L. García Mendivil, H. Santander Badules, G. Mercanti, E. Garrido Huéscar, N. Garatachea, R. Köhler, E. Pueyo, L. Ordovás (2023). microRNAs en envejecimiento cardiaco humano: dianas terapéuticas y biomarcadores, XII Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 11 (2023): Actas de la XII Jornada de Jóvenes Investigadores e Investigadoras del I3A - 15 de junio de 2023, https://doi.org/10.26754/jjii3a.20239029
S. Perez, S. Kontaxis, E. García2, S. Siddi, N. Cummins, S. Vairavan, F. Matcham, J.M. Haro, M. Hotopf, F. Lamers, B. Penninx, R. Dobson, V. Narayan, R. Bailón, A. Martín-Yebra, the RADAR-CNS consortium (2023). Monitorización de la depresión mediante el an´alisis de la circadianidad del ritmo card´ıaco proporcionado por un dispositivo wearable, pp. 343-346. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.
M. Javierre, M. Kloostermann, P. Van Dam, T. Eijsvogels, E. Pueyo, R. Bailón (2023) Análisis de la variabilidad de la frecuencia cardíaca en maratonianos, pp. 18-21. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.
S. Palacios, R. Smisek, K. Curila, U. Nguyen, F.W. Prinzen, J. Halamek, F. Plesinger, P. Jurak, J.P. Martínez, E. Pueyo (2023) Dispersión espacial de los tiempos de activación y repolarización asociada a diferentes modos de estimulación cardiaca, pp. 6-9. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.
C. Pérez, E. Pueyo, JP. Martínez, L. Sörnmo, P. Laguna (2023) Estimadores del retardo entre las series de QT y RR en registros ECG de prueba de esfuerzo: evaluación en simulación, pp. 606-609. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.
P. Armañac-Julián, A. Martín-Montero, S. Hietakoste, J. Lázaro, S. Kainulainen, D. Gozal, R. Hornero, P. Laguna, G. Gutiérrez-Tobal, E. Gil, R. Bailón (2023) Caracterización del Acoplo Cardiopulmonar en Pacientes Pediátricos con Apnea Obstructiva del Sueño, pp. 545-549. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.
N. Gómez, J. Ramírez, A. Martín-Yebra, MM. Demidova, P. Platonov, JP. Martínez, P. Laguna (2023) Los cambios en la morfolog´ıa del pico al fin de la onda T, cuantificados mediante “time-warping”, están asociados con la aparición de fibrilación ventricular en un modelo porcino de isquemia aguda, pp. 2-5. VLI Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Cartagena, España.

Ph.D. Thesis

Syed Hassaan Ahmed Bukhari (2023) Estimation of Serum Potassium and Calcium Concentrations from Electrocardiographic Depolarization and Repolarization Waveforms. Zaragoza University and University of Bordeaux
Laura García Mendívil (2023) Ex vivo, in vitro and in silico characterization of human cardiac aging and its impact on Arrhythmic risk. Zaragoza University
Chiara Celotto (2023) In silico characterization of atrial electrical activity modulation by the autonomic nervous system for atrial fibrillation management. Zaragoza University.
Jennifer Riccio (2023) Characterization of Atrial Propagation Patterns and Substrate using Novel Electrogram-Based Approaches in Multielectrode Catheters. Zaragoza University.

Patents

2022

Journals and Book

S. Sun, A. Folarin,et. al. RADAR-CNS consortium (2022) The utility of wearable devices in assessing ambulatory impairments of people with multiple sclerosis in free-living conditions, Computer Methods and Programs in Biomedicine 227, 107204, doi:10.1016/j.cmpb.2022.107204
Siddi S, Giné-Vázquez I, Bailon R, Matcham F, Lamers F, Kontaxis S, Laporta E, Garcia E, Arranz B, Dalla Costa G, Guerrero AI, Zabalza A, Buron MD, Comi G, Leocani L, Annas P, Hotopf M, Penninx BWJH, Magyari M, Sørensen PS, Montalban X, Lavelle G, Ivan A, Oetzmann C, White KM, Difrancesco S, Locatelli P, Mohr DC, Aguiló J, Narayan V, Folarin A, Dobson RJB, Dineley J, Leightley D, Cummins N, Vairavan S, Ranjan Y, Rashid Z, Rintala A, Girolamo G, Preti A, Simblett S, Wykes T, Pab Members, Myin-Germeys I, Haro JM (2022), On Behalf Of The Radar-Cns Consortium. Biopsychosocial Response to the COVID-19 Lockdown in People with Major Depressive Disorder and Multiple Sclerosis. J Clin Med. 2022 Dec 1;11(23):7163. doi: 10.3390/jcm11237163. PMID: 36498739; PMCID: PMC9738639.
Ramdas, S.; Judd, J.; Graham, S.E.; Ramírez, J.; et. al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids, American Journal of Human Genetics, Volume 109, 1366 - 1387, doi:10.1016/j.ajhg.2022.06.012
Kanoni, S.; Graham, S.E.; Wang, Y.; Ramírez, J.; et. al. Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis, Genome Biology, volume 23, issue 1, doi:10.1186/s13059-022-02837-1
K. Mountris, L. Dong, Y. Guan, S.N. Atluri, E. Pueyo (2022). A meshless fragile points method for the solution of the monodomain model for cardiac electrophysiology simulation. Journal of Computational Science, 65, 101880.
B. Zicher, J. Ibáñez, D. Farina, (2022). Beta inputs to motor neurons do not directly contribute to volitional force modulation. The Journal of Physiology, 1–13. https://doi.org/10.1113/JP283398
K. Mountris, E. Pueyo (2022). A meshless fragile points method for rule-based definition of myocardial fiber orientation. Computer Methods and Programs in Biomedicine, 226, 107164. doi: 10.1016/j.cmpb.2022.107164
Yengo, L., Vedantam, S., Marouli, E. et al. (2022) A saturated map of common genetic variants associated with human height. Nature, vol. 610. https://doi.org/10.1038/s41586-022-05275-y
Casula, E. P., Leodori, G., Ibáñez, J., Benussi, A., Rawji, V., Tremblay, S., Latorre, A., Rothwell, J. C., & Rocchi, L. (2022). The Effect of Coil Orientation on the Stimulation of the Pre-Supplementary Motor Area : A Combined TMS and EEG Study. Brain Sciences, 12(10), 1–15. https://doi.org/https://doi.org/10.3390/brainsci12101358
del Vecchio, A., Jones, R. H. A., Schofield, I. S., Kinfe, T. M., Ibáñez, J., Farina, D., & Baker, S. N. (2022). Interfacing Motor Units in Non-Human Primates Identifies a Principal Neural Component for Force Control Constrained by the Size Principle. The Journal of Neuroscience, 42(39):7386–7399, JN-RM-0649-22. https://doi.org/10.1523/JNEUROSCI.0649-22.2022
Montero-Calle, M. Flandes-Iparraguirre, K. Mountris, A. S de la Nava, N. Laita, R.M. Rosales, O. Iglesias-García, E.M. De-Juan-Pardo, F. Atienza, M.E. Fernández-Santos, E. Peña, M. Doblaré, J.J. Gavira, F. Fernández-Avilés, F. Prosper, E. Pueyo, M.M. Mazo Vega (2022). Fabrication of human myocardium using multidimensional modelling of engineered tissues. Biofabrication. Biofabrication 14, 045017 doi: 10.1088/1758-5090/ac8cb3.
V. Monasterio, E. Pueyo, J.F. Rodríguez-Matas, J. Carro (2022). Cardiac cells stimulated with an axial current-like waveform reproduce electrophysiological properties of tissue fibers. Computer Methods and Programs in Biomedicine. Volume 226, 107121 doi: 1016/j.cmpb.2022.107121
A. Hernández-Vicente, J. Marín-Puyalto, E. Pueyo, G. Vicente-Rodríguez, N. Garatachea (2022). Physical activity in centenarians beyond cut-point-based accelerometer metrics. International Journal of Environmental Research and Public Health. 19, 11384 doi: 10.3390/ijerph191811384
J. Riccio, A. Alcaine, S. Rocher, L. Martinez-Mateu, J. Saiz, E. Invers-Rubio, M. S. Guillem, J. P. Martínez, P. Laguna (2022), Atrial Fibrosis Identification with Unipolar Electrogram Eigenvalue Distribution Analysis in Multi-Electrode Arrays. Medical & Biological Engineering & Computing, doi: 10.1007/s11517-022-02648-3
R. Barrio, M. A. Martínez, S. Serrano, E. Pueyo (2022). Dynamical mechanism for generation of arrhythmogenic early afterdepolarizations in cardiac myocytes: Insights from in silico electrophysiological models. Physical Review E. 106, 024402. DOI: 10.1103/PhysRevE.106.024402
Lubel, E., Grandi Sgambato, B., Barsakcioglu, D. Y., Ibáñez, J., Tang, M.-X., & Farina, D. (2022). Kinematics of individual muscle units in natural contractions measured in vivo using ultrafast ultrasound. Journal of Neural Engineering, 19(5), 056005. https://doi.org/10.1088/1741-2552/ac8c6c
M. Rivolta, J. P. Martinez, R. Sassi P. Laguna (2022) Spatial Correlation Between Myocyte's Repolarization Times and their Alternans Drives T-Wave Alternans on the ECG. IEEE Journal of Biomedical and Health Informatics. vol. 26, n. 11, pp. 5372-5383, doi 10.1109/JBHI.2022.3195060
J. Ramirez, A. Kiviniemi, S. V. Duijvenboden, A. Tinker, P. LAmbiase, M. J. Junttila, J. Perkiömäki, M. Orini, P.Munroe (2022). ECG T-wave Morphology Variations Predict Ventricular Arrhythmic Risk in Low- and Moderate-risk Populations, JAHA: J Am Heart Assoc;11:e025897. doi: 10.1161/JAHA.121.025897
P. Armañac-Julián, S. Kontaxis, A. Rapalis, V. Marozas, P. Laguna, R. Bailón, E. Gil, J. Lázaro (2022) Reliability of Pulse Photoplethysmography Sensors: Coverage Using Different Setups and Body Locations, Front. Electron. 3:906324. doi: 10.3389/felec.2022.906324
A. Santos-Rodrigues, R. Augustauskas, M.Lukoševičius, P. Laguna, V. Marozas (2022) Deep-Learning-Based Estimation of the Spatial QRS-T Angle From Reduced-lead ECGs. Sensors, 22, 5414. https://doi.org/10.3390/s22145414
D. Cajal, D. Hernando, J. Lázaro, P. Laguna, E. Gil, R. Bailón (2022) Effects of Missing Data on Heart Rate Variability Metrics, Sensors, 22, 5774. doi:10.3390/s22155774
C. Albors, E. Lluch, J.F. Gomez, N. Cedilnik, K.A. Mountris, T. Mansi, S. Khamzin, A. Dokuchaev, O. Solovyova, E. Pueyo, M. Sermesant, R. Sebastian, H.G. Morales, O. Camara (2022) Meshless electrophysiological modeling of cardiac resynchronization therapy—benchmark analysis with finite-element methods in experimental data. Applied Sciences 12:6438, doi: 10.3390/app12136438
M. Bräcklein, D. Y. Barsakcioglu, J. Ibáñez, J. Eden, E. Burdet, C. Mehring, D. Farina (2022), The control and training of single motor units in isometric tasks are constrained by a common input signal Elife, 2;11:e72871. DOI:10.7554/eLife.72871
J. Ramírez, S. van Duijvenboden, W.J. Young, A. Tinker, P.D. Lambiase, M. Orini, P.B. Munroe (2022) Prediction of coronary artery disease and major adverse cardiovascular events using clinical and genetic risk scores for cardiovascular risk factors. Circulation – Genomics and Precision Medicine, 15:e003441 doi: 10.1161/CIRCGEN.121.003441.
M. Bräcklein, D. Y Barsakcioglu, A. Del Vecchio, J. Ibáñez, D. Farina (2022) Reading and modulating cortical beta bursts from motor unit spiking activity. J. Neurosci; doi: 10.1523/JNEUROSCI.1885-21.2022
A. Martín-Yebra, L. Sörnmo, P. Laguna, (2022) QT interval Adaptation to Heart Rate Changes in Atrial Fibrillation as a Predictor of Sudden Cardiac Death. IEEE Trans Biomed Eng. vol. 69, n.10, pp: 3109-3118, doi: 10.1109/TBME.2022.3161725
F. Palmieri, P. Gomis, D. Ferreira, E. Pueyo, J. P. Martínez, P. Laguna, J. Ramírez (2022) Weighted Time Warping Improves T-wave Morphology Markers Clinical Significance, IEEE Trans Biomed Eng. vol. 69, n. 9, pp. 2787- 2796 doi: 10.1109/TBME.2022.3153791
H. A. Bukhari, C. Sánchez, J. E. Ruiz, M. Potse, P. Laguna, E. Pueyo (2022) Monitoring of Serum Potassium and Calcium Levels in End-stage Renal Disease Patients by ECG Depolarization Morphology Analysis, Sensors, 22, 2951. doi: 10.3390/s22082951
M. D. Peláez-Coca, A. Hernando, J. Lázaro and E. Gil (2021) Impact of the PPG sampling rate in the pulse rate variability indices evaluating several fiducial points in different pulse waveforms, IEEE Journal of Biomedical and Health Informatics, vol. 26, n. 2, pp. 539-549. doi: 10.1109/JBHI.2021.3099208
Eden J, Bräcklein M, Ibáñez J, Barsakcioglu DY, Di Pino G, Farina D, Burdet E & Mehring C (2022). Principles of human movement augmentation and the challenges in making it a reality. Nat Commun 13, 1345.
Matas, J. F. R., Berenfeld, O., Loewe, A., Corino, V., Martínez, J. P., eds. (2022). Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88974-690-3
Liu, S., Han, J., Puyal, E. L., Kontaxis, S., Sun, S., Locatelli, P., Dineley, J., Pokorny, F. B., Dalla Costa, G., Leocani, L., Guerrero, A. I., Nos, C., Zabalza, A., Soelberg Sørensen, P., Buron, M., Magyari, M., Ranjan, Y., Rashid, Z., Conde, P., Stewart, C., Folarin, A. A., Dobson, R. J. B., Bailón, R., Vairavan, S., Cummins, N., Narayan, V. A., Hotopf, M., Comi, G., Schuller, B., & RADAR-CNS Consortium. (2022). Fitbeat: COVID-19 estimation based on wristband heart rate using a contrastive convolutional auto-encoder. Pattern recognition, 123, 108403.
O. Berenfeld, V. D. A. Corino, A. Loewe, J. P. Martínez, J. F. Rodriguez (2022) Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment, Frontiers in Physiology, vol. 13, Article 848096, pp.1-4 doi: 10.3389/fphys.2022.848096
L. García-Mendívil, M. Pérez-Zabalza, K. Mountris, S. Duwé, N. Smisdom, M. Pérez, L. Luján, E. Wolfs, R.B. Driesen, J.M. Vallejo-Gil, P.C. Fresneda-Roldán, J. Fañanás-Mastral, M. Vázquez-Sancho, M. Matamala-Adell, J.F. Sorribas-Berjón, J.A. Bellido-Morales, F.J. Mancebón-Sierra, A.S. Vaca-Núñez, C. Ballester-Cuenca, A. Oliván-Viguera, E. Diez, L. Ordovás, E. Pueyo (2022). Analysis of age-related left ventricular collagen remodeling in living donors: implications in arrhythmogenesis. iScience 25, 103822 doi: https://doi.org/10.1016/j.isci.2022.103822.
S. H. A. Bukhari, C. Sánchez, S. Srinivasan, F. Palmieri, M. Potse, P. Laguna, E. Pueyo (2022) Estimation of Potassium Levels in Hemodialysis Patients by T wave Nonlinear Dynamics and Morphology Markers. Computers in Biology and Medicine, 143, 105304 doi:10.1016/j.compbiomed.2022.105304
F.J. Sánchez, E. Pueyo, E.R. Diez (2022). Strain echocardiography to predict postoperative atrial fibrillation. Int. J. Mol. Sci. 23: 1355.
D. Han, S. K. Bashar, J. Lazaro, F. Mohagheghia, A. Peitzsch, N. Nishita, E. Ding, E. L. Dickson, D. DiMezza, J. Scott, C. Whitcomb, T. P. Fitzgibbons, D. D. McManus, K. H. Chon (2022), A Real-Time PPG Peak Detection Method for Accurate Determination of Heart Rate during Sinus Rhythm and Cardiac Arrhythmia, Biosensors, 12(2), 82, DOI: 10.3390/bios12020082
A. Hernando, H. Posada-Quintero, M.D. Peláez-Coca, E. Gil, K. Chon. (2021) Autonomic Nervous System characterization in hyperbaric environments considering respiratory component and non-linear analysis of Heart Rate Variability, Computer Methods and Programs in Biomedicine.Volume 214, 106527, pp. 1-13, doi: 10.1016/j.cmpb.2021.106527
N. M S de Groot, D. Shah, P. M Boyle, E. Anter, G. D Clifford, I. Deisenhofer, T. Deneke, P. van Dessel, O. Doessel, P. Dilaveris, F. R Heinzel, S. Kapa, P. D Lambiase, J. Lumens, P. G Platonov, T. Ngarmukos, J. P. Martinez, A. Olaya Sanchez, Y. Takahashi, B. P Valdigem, Alle-Jan van der Veen, K. Vernooy, R. Casado-Arroyo (co-chair) (2021), ESC Scientific Document Group, Critical appraisal of technologies to assess electrical activity during atrial fibrillation: a position paper from the European Heart Rhythm Association and European Society of Cardiology Working Group on eCardiology in collaboration with the Heart Rhythm Society, Asia Pacific Heart Rhythm Society, Latin American Heart Rhythm Society and Computing in Cardiology, Volume 24, Issue 2, February 2022, Pages 313–330, EP Europace, euab254, https://doi.org/10.1093/europace/euab254

Conference Proceedings

C. Moreno, A. Martin, A. Savelev, P. Platonov, P. Laguna, J. P. Martínez (2022), Analysis of P-wave Changes for Prediction of Atrial Fibrillation Episodes. Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.320
C. Celotto, C. Sánchez, M. Abdollahpur, F. Sandberg, J. F. Rodriguez, P. Laguna, E. Pueyo (2022) Effects of Acetylcholine Release Spatial Distribution on the Frequency of Atrial Reentrant Circuits: a Computational Study. Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.396
N. Gómez Fonseca, J. Ramírez, P. Laguna, J. P. Martínez (2022) Time-Warping Based End-of-T-Wave Shape Marker Reflects Repolarization Changes During Ischemia Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.397
S. H. A. Bukhari, C. Sánchez, P. Laguna, M. Potse, E. Pueyo (2022) Inter-individual Differences in Cell Composition across the Ventricular Wall May Explain Variability in ECG Response to Serum Potassium and Calcium Variations Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.166
M. Gomez, J. Carro, E. Pueyo, V. Monasterio (2022) An in Silico Investigation into the Role of SK Channels in Failing Ventricular Myocytes Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland DOI: 10.22489/CinC.2022.228.
R. Rosales, K. Mountris, M. Doblaré, M. Mazo, E. Pueyo (2022) Ventricular Conduction System Modeling for Electrophysiological Simulation of the Porcine Heart Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.030
S.H.A. Bukhari, C. Sánchez, E. Pueyo, M. Potse (2022) - Accelerating Stabilization of Whole-heart Models after Changes in Cycle Length Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.388
C. Sales-Bellés, S. Palacios, J. Melero, I. Julián, J. Ramos, J. P. Martínez, A. Minchole, E. Pueyo (2022) - Right Ventricular vs Left Bundle Branch Pacing-Induced Changes in ECG Depolarization and Repolarization Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.340
M. Usón, J. de Bie, R. Maestri, M. T. La Rovere, J. P. Martínez, A. Martin (2022) Cosinor-Based Circadianity of T-Wave Alternans Activity as a Predictor of Sudden Cardiac Death in Heart Failure: a Post-Hoc Analysis of the GISSI-HF Holter Substudy Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI: 10.22489/CinC.2022.341
H. Naderi, J. Ramírez, S. van Duijvenboden, E. Ruiz-Pujadas, L. Wang, K. Lekadir, S. Petersen, P. Munroe (2022) Classifying Left Ventricular Hypertrophy from Extracted Morphological Electrocardiogram Biomarkers using Random Forest, Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland.
M. Orini, S. van Duijvenboden, J. Ramirez, A. Tinker, P. Munroe, P. Lambiase (2022) Uncoupling Between Heart Rate Variability and Heart Rate During Exercise and Recovery as a Predictor of Cardiovascular Events Proceedings of the XLVIII International Conference on Computing in Cardiology. Tampere, Finland. DOI:10.22489/CinC.2022.229
P. Armañac-Julián, A. Martín-Montero, J. Lázaro, S. Kontaxis, D. Álvarez, D. Gozal, R. Hornero, P. Laguna, G. Gutiérrez-Tobal, R. Bailón and E. Gil (2022) Changes in HRV metrics during sleep apnea episodes in children, European Study Group on Cardiovascular Oscillations (ESGCO), Štrbské Pleso (Slovakia)
D. Cajal, E. Gil, P. Laguna, C. Varon, D. Testelmans, B. Buyse, C. Jensen, R. Hoare, R. Bailón and J. Lázaro (2022) Sleep apnea severity stratification by an FFT-based PPG-derived index, European Study Group on Cardiovascular Oscillations (ESGCO), Štrbské Pleso (Slovakia)
M. Javierre, M. Posadas-de Miguel, J. Lázaro, T. Castro, E. García, E. Gil, C. de la Cámara, J. Aguiló, R. Bailón and S. Kontaxis (2022), Quantification of stress and depression level posed by COVID-19 in first-line healthcare workers, European Study Group on Cardiovascular Oscillations (ESGCO), Štrbské Pleso (Slovakia)
D. Cajal, M. Posadas-de Miguel, C. de la Cámara, S. Kontaxis, J. Lázaro, R. Bailón (2022) Smartphone PPG validation for a depression assessment protocol IEEE International Conference on e-Health and Bioengineering - EHB 2022 - 10-th Edition. 17-19 November 2022, Hybrid Conference, Iasi - Romania
García-Mendívil, L; Hernández-Bellido, N; Sánchez-Barat, M; Pérez Zabalza, M; Garrido-Huéscar, E; Oliveros, J.C; Torres-Pérez R, Ramos-Marqués, E; Pueyo, E; Ordovás, L (2022), Envejecimiento cardíaco humano: transcriptómica y desarrollo de modelos celulares, II Congreso Anual de Estudiantes de Doctorado (CAED), Universidad Miguel Hernández, Elche.
García-Mendívil, L; Pérez Zabalza, M; Mountris, K; Mancebón-Sierra, F.J; Vaca-Núñez, A.S.; Duwé, S; Ordovás, L, Pueyo, E (2022) Caracterización del remodelado del colágeno asociado a la edad en el ventrículo izquierdo humano de donantes vivos y sus implicaciones en la generación de arritmias. XI Jornada de Jóvenes Investigadores del I3A. Póster 2022
C. Sales, S. Palacios, J. Melero, I. Julián, J. Ramos, J. P. Martínez, A. Mincholé, E. Pueyo (2022) Assessment and optimization of conduction system pacing for anti-bradycardia pacemaker therapy, STAFF-MALT Symposium 2022, Senohraby Czech Republic.
C. Sales, E. Pueyo, I. Julián, L. Sorinas, M. Cabrera, J. R. Ruiz, J. Ramos (2022) Cambios en la despolarización y repolarización producidos por la estimulación de rama izquierda frente a la estimulación convencional, Ritmo22, Granada España.
J. Melero, C. Sales, I. Julián, J. R. Ruiz, E.Pueyo J. Ramos (2022) Estimulación de rama izquierda frente a estimulación de ventrículo derecho: cambios en la despolarización y en la repolarización, Congreso de la Salud Cardiovascular, Palma de Mallorca España.
C. Sales, J. Melero, I. Julián, J. Ramos, A. Mincholé, E. Pueyo (2022) Comparación de los efectos de la estimulación cardíaca convencional y la estimulación de rama izquierda sobre la despolarización y repolarización ventricular en el ECG, Jornadas de Jóvenes Investigadores del I3A, Zaragoza ESpaña. https://doi.org/10.26754/jjii3a.20227001
A. Pérez-Martínez; A. Oliván-Viguera; E. Pueyo. (2022) La endotelina-1 aumenta la heterogeneidad de la repolarización ventricular en cerdos con infarto crónico de miocardio. XI Jornada de Jóvenes Investigadores e Investigadoras del I3A. Zaragoza, España "Vol. 10 (2022): Actas de la XI Jornada de Jóvenes Investigadores e Investigadoras del I3A - 16 de junio de 2022".https://doi.org/10.26754/jjii3a.20227030
A. Pérez-Martínez; E. Pueyo; A. Oliván-Viguera (2022). Endothelin-1 enhances transmural heterogeneities in healthy porcine ventricular myocardium. 46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE). Toledo, España.
A. Oliván-Viguera; A. Pérez-Martínez; L. García-Mendívil; M. López-Yus; F. J. Mancebón-Sierra; A. S. Vaca-Núñez; A. Bellido-Morales; J. F. Sorribas-Berjón; M. Matamala-Adell; M. Vázquez-Sancho; J. Fañanás-Mastral; J. M. Vallejo-Gil; C. Ballester-Cuenca; M. Pérez-Zabalza; R. Köehler; J. M. Arbonés-Mainar; E. Pueyo (2022). SK channels characterization in the human ventricle: differences in expression levels and electrophysiological role in non-diseased and heart failure ventricles. 46th European Working Group on Cardiac Cellular Electrophysiology (EWGCCE). Toledo, España
A. Oliván-Viguera; A. Pérez-Martínez; E. Pueyo (2022). Endothelin-1 amplifies ventricular repolarization heterogeneities in chronic myocardial infarction pigs. Frontiers in CardioVascular Biomedicine (FCVB) 2022. Budapest, Hungría "Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022, https://doi.org/10.1093/cvr/cvac066.023
A. Pérez-Martínez; L. García-Mendívil; M. López-Yus; F. J. Mancebón-Sierra; A. S. Vaca-Núñez; C. Ballester-Cuenca; M. Pérez-Zabalza; R. Köehler; E. Pueyo; A. Oliván-Viguera (2022). SK channels contribution to ventricular electrophysiology in heart failure patients. Frontiers in CardioVascular Biomedicine (FCVB) 2022. Budapest, Hungría. "Cardiovascular Research, Volume 118, Issue Supplement_1, June 2022, cvac066.022". https://doi.org/10.1093/cvr/cvac066.022
A. Pérez-Martínez; A. Bellido-Morales; J. Fañanás-Mastral; M. Matamala-Adell; J. F. Sorribas-Berjón; J. M. Vallejo-Gil; M. Vázquez-Sancho; C. Ballester-Cuenca; A. Oliván-Viguera; E. Pueyo (2022). Caracterización del papel de los canales SK en el remodelado ventricular producido por insuficiencia cardíaca. II Congreso Anual Internacional de Estudiantes de Doctorado (CAED). Elche, España.
A. Oliván-Viguera, A. L. García-Otín, J. Lozano-Gerona, E. Abarca-Lachen, A. J. García-Malinis, K. L. Hamilton, Y. Gilaberte, E. Pueyo, R. Köhler (2022). Cell damage and apoptosis induced by TRPV4 activation in human melanoma cells and Hacat keratinocytes. Reunión Anual de Sociedades de Biociencias 2022, Reunión conjunta SAIC SAI & FAIC SAFIS 2022. Buenos Aires, Argentina. "Medicina. Buenos Aires, Vol. 82 Supl. V - 2022"
E. Garrido-Huéscar, L. García-Mendivil, Hernández-Bellido N, M. Sánchez-Barat, M. Pérez-Zabalza, E. Pueyo, L. Ordovás(2022). Development of new human models to determine age related cardiotoxicity of drugs, Stem cells and stem cell models in disease & health (SCMiDH). Hasselt, Belgium. Poster.
E. Garrido-Huéscar, L. Ordovás, E. Pueyo (2022). Development of new computational models to evaluate age-related drugs cardiotoxicity. XI Jornada de Jóvenes Investigadores del Instituto de Investigación en Ingeniería de Aragón (I3A). Zaragoza, Spain. Oral communication.
E. Garrido-Huéscar, L. Ordovás, E. Pueyo (2022). Development of new human models to determine age-related cardiotoxicity of drugs. I ipIBA Day, 2022. Zaragoza, Spain. Poster.
E. Garrido-Huéscar, L. Ordovás, E. Pueyo (2022) Development of new human models to determine age-related cardiotoxicity of drugs. Frontiers in CardioVascular Biomedicine 2022, Budapest, Hungary. Poster.
E. Garrido-Huéscar, L. Ordovás, E. Pueyo (2021). Human cardiac models for investigation of age-related cardiotoxic effects of drug compounds. XV CIBER-BBN Annual Conference. Valencia, Spain. Video presentation.
Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L;Pueyo, E; Hernández-Ainsa, S; Ordovás, L (2022) Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA, XI Jornada de Jóvenes Investigadores, Zaragoza (Spain). Poster presentation.
Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L (2022) Towards advanced cardiac miRNA therapies through DNA-based nanostructures, Cardiovascular Research 118 (Supplement_1), Frontiers in CardioVascular Biomedicine 2022, Budapest (Hungary). Poster presentation.
Hernández-Bellido, N; Postigo, A; Orrite, C; Garrido-Huéscar, E; García-Mendivil, L; Pueyo, E; Hernández-Ainsa, S; Ordovás, L (2022) Terapias cardiacas avanzadas con microRNAs basadas en nanoestructuras de DNA, I iPIBA Day, Zaragoza (Spain). Poster presentation.
Hernández-Bellido, N; Köhler, R; Ordovás, L (2022) MicroRNAs cardiacos en envejecimiento: Dianas terapéuticas y biomarcadores, I iPIBA Day, Zaragoza (Spain). Oral communication
Postigo, A; Marín, P; Hernández-Bellido, N; Ordovás, L; del Barrio, J; Hernández-Ainsa, S (2022)Development of tailored DNA nanostructures for anticancer drug delivery, XXXVIII Reunión Bienal RSEQ, Granada (Spain). Poster presentation.
Postigo, A; Hernández-Bellido, N; Ordovás, L; del Barrio, J; Hernández-Ainsa, S (2022). DNA nanostructures customized for therapeutic delivery, 5th Spanish Conference on Biomedical Applications of Nanomaterials SBAN, Madrid (Spain). Oral communication.
A.Velarte, A.Otín, A.Guimera, E.Pueyo, R.Villa (2022) Improving Signal Stability in a Multi-Electrode Array (MEA) System for Cardiac Biopsies Proceedings of the 37th Conference on Design of Circuits and Integrated Systems. Pamplona, Spain.
A.Velarte, A.Otín,E.Pueyo (2022) Análisis y modelado de la impedancia de una matriz de microelectrodos (MEA) fabricados en oro mediante platino negro XI Jornada de Jóvenes Investigadores e Investigadoras del I3A.

Ph.D. Thesis

Flavio Palmieri (2022), Serum Potassium Concentration Monitoring by ECG Time Warping Analysis on the T wave, Universitat Politècnica de Catalunya
Adrián Hernández Vicente (2022), Actividad física y electrofisiología cardíaca: a propósito del envejecimiento y la longevidad excepcional, Universidad de Zaragoza

Patents

2021

Journals and Books

L. García, D Mediano, A. Hernaiz, D. Sanz, F. Vázquez, B. Marín, O. López, A. Otero, J. Badiola, P. Zaragoza, L. Ordovás, R. Bolea, I Martín (2022) Effect of Scrapie Prion Infection in Ovine Bone Marrow-Derived Mesenchymal Stem Cells and Ovine Mesenchymal Stem Cell-Derived Neurons. Animals 2021, 11, 1137 doi:10.3390/ani11041137
E. Pueyo (2022). Modelización matemática y simulación computacional de la variabilidad espacio-temporal en la actividad eléctrica cardíaca. Rev. Real Academia de Ciencias. Zaragoza, vol. 76, pp. 7-54.
K. P. Chatzipapas, D. Plachouris, P. Papadimitroulas, K. A. Mountris, J. Bert, D.Visvikis, D. Mihailidis, G. C. Kagadis (2021) Standardization and Validation of Brachytherapy Seeds. Modelling Using GATE and GGEMS Monte Carlo Toolkits, Cancers, vol. 13, 5315. doi:10.3390/cancers13215315
D. Plachouris, K. Mountris, P. Papadimitroulas, T. Spyridonidis, K. Katsanos, D. Apostolopoulos, N. Papathanasiou, J. Hazle, D. Visvikis, and G. Kagadis, (2021) Clinical Evaluation of a Three-Dimensional Internal Dosimetry Technique for Liver Radioembolization with 90Y Microspheres Using Dose Voxel Kernels. Cancer Biotherapy & Radiopharmaceuticals. vol. 36, n.10, doi: 10.1089/cbr.2020.4554
G. Navarra‐Ventura, G. Gomà, C. de Haro, M. Jodar, L. Sarlabous, D. Hernando, R. Bailón, A. Ochagavía, L. Blanch, J. López‐Aguilar, S. Fernández‐Gonzalo (/2021) Virtual Reality‐Based Early Neurocognitive Stimulation in Critically Ill Patients: A Pilot Randomized Clinical Trial. Journal of Personalkized Medicine. Pers. Med. 2021, 11, 1260. https://doi.org/10.3390/jpm11121260
R. Lazazzera, P. Laguna, E. Gil, G. Carrault (2021). Proposal for a Home Sleep Monitoring Platform employing a Smart Glove, Sensors, 21, 7976. https://doi.org/10.3390/s21237976
M. González del Castillo, D. Hernando, M. Orini, P. Laguna, J. Viik, R. Bailón, E. Pueyo (2021). QT variability unrelated to RR variability during stress testing for identification of coronary artery disease. Phil. Trans. R. Soc. A. 379: 20200261. doi: 10.1098/rsta.2020.0261
M. Luft, J. Klepetko, S. Muceli, J. Ibáñez, V. Tereshenko, C. Festin1, G. Laengle, O. Politikou, U. Maierhofer, D. Farina, O. C. Aszmann, K. D. Bergmeister (2021). Proof of concept for multiple nerve transfers to a single target muscle. eLife 2021;10:e71312. DOI: https:// doi. org/ 10. 7554/ eLife. 71312
S. Palacios, I. Cygankiewicz, A. Bayés de Luna, E. Pueyo, J. P. Martínez (2021). Periodic Repolarization Dynamics as Predictor of Risk for Sudden Cardiac Death in Chronic Heart Failure Patients. Scientific Reports, 11:20546, doi: doi.org/10.1038/s41598-021-99861-1
R. Espinosa, R. Bailón, P. Laguna (2021) Two-dimensional EspEn: A new approach to analyze image texture by irregularity, Entropy 2021, 23, 1261. https://doi.org/10.3390/ e23101261
D. Sokas, B. Paliakaite, A. Rapalis, V. Marozas, R. Bailón and A. Petrenas A (2021) Detection of Walk Tests in Free-Living Activities Using a Wrist-Worn Device. Front. Physiol. 12:706545. doi: 10.3389/fphys.2021.706545
C. Böck, P. Kovács, P. Laguna, J. Meier, M. Huemer (2021) ECG Beat Representation and Delineation by means of Variable Projection, IEEE Trans Biomed Eng. , vol. 68, n. 10, pp. 2997-3008, doi: 10.1109/TBME.2021.3058781
A. Hernández-Vicente, D. Hernando, G. Vicente-Rodríguez, R. Bailón, N. Garatachea, E. Pueyo (2021). ECG ventricular repolarization dynamics during exercise: temporal profile, relation to heart rate variability and effects of age and physical health, International Journal of Environmental Research and Public Health, 18, 9497, doi: 10.3390/ijerph18189497
J. Riccio, A. Alcaine, S. Rocher, L. Martínez-Mateu, S. Laranjo, J. Saiz, P. Laguna, J. P. Martínez (2021) Characterization of Atrial Propagation Patterns and Fibrotic Substrate With a Modified Omnipolar Electrogram Strategy in Multi-Electrode Arrays. Front. Physiol. 12:674223. doi: 10.3389/fphys.2021.674223
P. Armanac-Julián, D. Hernando, J. Lazaro, C. de Haro, R. Magrans, J. Morales, J. Moeyersons, L. Sarlabous, J. Lopez-Aguilar, C. Subira, R. Fernandez, M. Orini, P. Laguna, C. Varon, E. Gil1, R. Bailon, and L. Blanch (2021) Cardiopulmonary Coupling Indices to Assess Weaning Readiness from Mechanical Ventilation. Scientific Reports. 11:16014, doi: 10.1038/s41598-021-95282-2
C. Celotto, C. Sanchez, K. A. Mountris, P. Laguna, E. Pueyo (2021), Location of Parasympathetic Innervation Regions from Electrograms to Guide Atrial Fibrillation Ablation Therapy: An In Silico Modeling Study, Frontiers in Physiology,12:674197, doi: 10.3389/fphys.2021.674197
R. Barrio, M.A. Martínez, E. Pueyo, S. Serrano (2021). Dynamical analysis of early afterdepolarization patterns in a biophysically-detailed cardiac model, Chaos, 31, 073137; doi: 10.1063/5.0055965.
H. A. Bukhari, F. Palmieri, J. Ramirez, P. Laguna, J. E. Ruiz, D. Ferreira, M. Potse, C. Sanchez, E. Pueyo (2021) Characterization of T Wave Amplitude, Duration and Morphology Changes During Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate, IEEE Trans Biomed Eng. vol. 68, n. 8, pp. 2467-2478 doi: 10.1109/TBME.2020.3043844
J. Milagro, L. Soto-Retes, J. Giner, C. Varon, P. Laguna, R. Bailón, V. Plaza, E. Gil (2021) Asthmatic Subjects Stratification Using Autonomic Nervous System Information, Biomedical Signal Processing and Control, n. 69, 102802, pp. 1-8, doi: 10.1016/j.bspc.2021.102802.
S. K. Bashar, M.-B. Hossain, J. Lazaro, E. Y. Ding, Y. Noh , C. H. Cho, D. D. McManus, T. P. Fitzgibbons, K. H. Chon, (2021) Feasibility of atrial fibrillation detection from a novel wearable armband device, Cardiovascular Digital Health Journal, Vol 2, No 3, pp. 179-191 doi:10.1016/j.cvdhj.2021.05.004
E. Ramos-Marquès, . García-Mendívil, M. Pérez-Zabalza, H. Santander-Badules, S. Srinivasan, J. C. Oliveros, R. Torres-Pérez, A. Cebollada, J. M. Vallejo-Gil,| P. C. Fresneda-Roldán, J. Fañanás-Mastral, M. Vázquez-Sancho, M. Matamala-Adell, J. F. Sorribas-Berjón, J. A. Bellido-Morales, F. J. Mancebón-Sierra, A. S. Vaca-Núñez, C. Ballester-Cuenca, M. Jiménez-Navarro, J. M. Villaescusa, E. Garrido-Huéscar, M Segovia-Roldán, A. Oliván-Viguera, C. Gómez-González, G. Muñiz, E. Diez, L. Ordovás, E. Pueyo (2021) Chronological and biological aging of the human left ventricular myocardium: Analysis of microRNAs contribution, Aging Cell. 2021;00:e13383, pp. 1-16, doi: 10.1111/acel.13383
G. Luongo, L. Azzolin, S. Schuler, M. Rivolta, T. Almeida, J. P. Martínez, D. Soriano, A. Luik, A. Jadidi, O. Dössel, R. Sassi, P. Laguna, A. Loewe (2021) Machine learning enables non-invasive prediction of atrial fibrillation driver location and acute pulmonary vein ablation success using the 12-lead ECG, Cardiovascular Digital Health Journal. vol 2, n 2, pp. 126-136, doi: 10.1016/j.cvdhj.2021.03.002
JF MoralesTellez, J. Moeyersons, P. Armanac, M. Orini, L. Faes, S. Overeem, M. Van Gilst, J. Van Dijk, SV. Huffel, R. Bailon, C. Varon (2021) Model-Based Evaluation of Methods for Respiratory Sinus Arrhythmia Estimation. IEEE Trans Biomed Eng. vol. 68, n. 6, pp. 1882-1893, doi: 10.1109/TBME.2020.3028204. PMID: 33001798.
F. Palmieri, P. Gomis, J. E. Ruiz, D. Ferreira, A. Martín-Yebra, E. Pueyo, J. P. Martínez, J. Ramírez, P. Laguna (2021) ECG-based Monitoring of Blood PotassiumConcentration: Periodic versus Principal Componentas Lead Transformation for Biomarker Robustness, Biomedical Signal Processing and Control, vol. 68, 102719, pp. 1-11, doi: 10.1016/j.bspc.2021.102719
M. D. Pelaez-Coca, A. Hernando, M. T. Lozano Albalate, C. Sanchez, D. Izquierdo and E. Gil (2021), "Photoplethysmographic Waveform and Pulse Rate Variability Analysis in Hyperbaric Environments," in IEEE Journal of Biomedical and Health Informatics, vol. 25, n. 5, pp. 1550-1560, doi: 10.1109/JBHI.2020.3020743.
P. Taggart, E. Pueyo, S.V. Duijvenboden, B. Porter, M. Bishop, D.A. Sampedro-Puente, M. Orini, B. Hanson, C.A. Rinaldi, J.S. Gill, P. Lambiase (2021). Emerging evidence for a mechanistic link between low-frequency oscillation of ventricular repolarization measured from the electrocardiogram T-wave vector and arrhythmia. Europace, euab009, doi: 10.1093/europace/euab009.
R. Lazazzera , M. Deviaene , C. Varon , B. Buyse, D. Testelmans , P. Laguna , E. Gil , and G. Carrault (2021). Detection and Classiﬁcation of Sleep Apnea and Hypopnea using PPG and SpO2 signals, IEEE Transactions Biomedical Engineering. vol. 68, n. 5, pp. 1495-1506 doi: DOI 10.1109/TBME.2020.3028041
K.A. Mountris, E. Pueyo (2021) A dual adaptive explicit time integration algorithm for efficiently solving the cardiac monodomain equation, Int J Numer Meth Biomed Engng; e3461 doi: 10.1002/cnm.3461
F. Palmieri, P. Gomis, J. E. Ruiz, D. Ferreira, A. Martín-Yebra, E. Pueyo, J. P. Martínez, J. Ramírez, P. Laguna (2021) Nonlinear T-wave Time Warping-based Sensing Model for Non-invasive Personalized Blood Potassium Monitoring in Hemodialysis Patients. Sensors, 21, 2710. doi: 10.3390/s21082710
S. Kontaxis, E. Gil, V. Marozas, J. Lázaro, E. García, M. Posadas-de Miguel, S. Siddi, M Luisa Bernal, J. Aguiló, J. M. Haro, C. de la Camara, P. Laguna, and R. Bailón (2021) Photoplethysmographic Waveform Analysis for Autonomic Reactivity Assessment in Depression, IEEE Transactions Biomedical Engineering. vol. 68, n. 4, pp. 1273-1281, doi: 10.1109/TBME.2020.3025908
M. Segovia-Roldán, E.R. Diez, E. Pueyo (2021). Melatonin to rescue the aged heart: antiarrhythmic and antioxidant benefits. Oxidative Medicine and Cellular Longevity, Volume 2021, Article ID 8876792, pp.1-18, doi:10.1155/2021/8876792
J. Lázaro, N. Reljin, R. Bailón, E. Gil, Y. Noh, P. Laguna, and K. H. Chon, (2021) Electrocardiogram Derived Respiratory Rate Using a Wearable Armband. IEEE Transactions Biomedical Engineering. vol. 68, n. 3, pp. 1056-1065, doi: 10.1109/TBME.2020.3004730
J. R. Bragard, O. Camara, B. Echebarria, L. Gerardo Giorda, E. Pueyo, J. Saiz, R. Sebastián, E. Soudah, M. Vázquez (2021). Cardiac Computational Modeling. Rev Esp Cardiol;74(1):65–71 doi: 10.1016/j.rec.2020.05.024.
F. Palmieri, P. Gomis, D. Ferreira, J. E. Ruiz, B. Bergasa, A. Martín-Yebra, H. A. Bukhari, E. Pueyo, J. P. Martínez, J. Ramírez, and P. Laguna (2021) Monitoring Blood Potassium Concentration in Hemodialysis Patients by Quantifying T-wave Morphology Dynamics, Scientific reports,11:3883 doi: 10.1038/s41598-021-82935-5
J. Milagro, A. Hernández-Vicente, D. Hernando, J.A. Casajús, N. Garatachea, R. Bailón, E. Pueyo (2021). Estimation of the second ventilatory threshold through ventricular repolarization profile analysis. Scand J Med Sci Spor, 31:339–349, doi:10.1111/sms.13849
M. V. Sanchez-Vivesa, A. Barbero-Castilloa , M. Perez-Zabalzac , R. Reigd (2021). GABAB receptor-modulation of thalamocortical dynamics and synaptic plasticity. Journal Neursicnece, Neuroscience 456, pp.131–142 doi: 10.1016/j.neuroscience.2020.03.011
A. Hernández-Vicente, D. Hernando, J. Marín-Puyalto, G. Vicente-Rodríguez, N. Garatachea, E Pueyo, R. Bailón (2021) Validity of the Polar H7 Heart Rate Sensor for Heart Rate Variability Analysis during Exercise in Different Age, Body Composition and Fitness Level Groups. Sensors, 21, 902. doi: 10.3390/s21030902
G. Jimenez‑Perez, A. Alcaine & O. Camara (2021) Delineation of the electrocardiogram with a mixed‑quality‑annotations dataset using convolutional neural networks. Scientifc Reports 11:863, doi: 10.1038/s41598-020-79512-7
S. Solbiati, A. Martin-Yebra, P. Vaïda, E. Caiani (2021) Evaluation of Cardiac Circadian Rhythm Deconditioning Induced by 5-to-60 Days of Head-Down Bed Rest. Front. Physiol. 11:612188. doi: 10.3389/fphys.2020.612188
D. A. Sampedro-Puente, F. Raphel, J. Fernandez-Bes, P. Laguna, D. Lombardi, E Pueyo (2021) Characterization of Spatio-Temporal Cardiac Action Potential Variability at Baseline and under -Adrenergic Stimulation by Combined Unscented Kalman Filter and Double Greedy Dimension Reduction, IEEE Journal of Biomedical and Health Informatics, v.. 25, n. 1. pp. 276-288 doi: 10.1109/JBHI.2020.2984647

Conference Proceedings

S. Palacios, I. Cygankiewicz, A. Bayés-de-Luna, J. P. Martínez, E. Pueyo (2021) Estudio de la dinámica periódica de la repolarización para la predicción de muerte súbita en pacientes con insuficiencia cardíaca crónica, I Congreso Anual de Estudiantes de Doctorado (CAED). Universidad Miguel Hernandez, Elche
M. Gómez, J. Carro, E. Pueyo, V. Monasterio (2021) Modificación de un modelo de miocito ventricular humano para
representar el papel de los canales SK en insuficiencia cardiaca. XXXIX Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Madrid, España.
F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, E. Pueyo, J.P. Martínez, P. Laguna, J. Ramírez (2021) Time-Warping” ponderado sobre la onda T para Reducir el Impacto de Errores de Delineación: Implicaciones Clínicas. XXXIX Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Madrid, España.
J. Riccio. A. Alcaine, S. Rocher, J. Saiz, J. P. Martínez, P. Laguna, "Analysis of Unipolar Electrogram Eigenvalue Dispersion for the Detection of Atrial Fibrosis", Proceedings of Atrial Signals 2021 (2021), pag. 12, doi:10.5445/IR/1000138459.
C. Pérez, A. Martín-Yebra, J. Viik, J. P. Martínez, E. Pueyo, P. Laguna (2021). Spatial ECG filtering by Periodic component analysis for improved QT delineation in stress test recordings. -55th Asilomar Conference on Signals, Systems and Computers.
S. Kontaxis, J. Lazaro, E. Gil, P. Laguna, and R. Bailón (2021) The Added Value of Nonlinear Cardiorespiratory Coupling Indices in the Assessment of Depression. 43st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), ?????????
K. A. Mountris, M. Doblaré, E. Pueyo (2021) Image-based Cardiac Electrophysiology Simulation through the Meshfree Mixed Collocation Method, 43st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
M. Sein-Echaluce, M. D. Peláez, D. Izquierdo, A. Hernando, M. T. Lozano (2021). Comparison of classical indices of Pulse/Heart RateVariability from sensor Polar OH1 and ECG, Proceedings of the 43st Annual International Conferenceof the IEEE Engineeringin Medicine & BiologySociety(EMBC).
C. Pérez, E. Pueyo, J. P. Martínez, P. Laguna 2021 Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings-International Society for Computerized Electrocardiology -ISCE-2020
P. Laguna, J.P. Martinez. (2021) Guiding ablation from EGM characteristics, Key Note talk, Atrial Signals 2021
A. Martin-Yebra (2021) QT adaptation to heart rate changes in AF patients. 17 Staff/Malt Conference, Sirolo, Italy
C. perez (2021) Characterization of impaired ventricular repolarization by quantification of QT delay after heart rate changes in stress test, 17 Staff/Malt Conference, Sirolo, Italy
S. H. A. Bukhari, P. Laguna, M. Potse, C. Sánchez, E. Pueyo (2021) QRS Slopes for Potassium and Calcium Monitoring in End-Stage Renal Disease Patients, Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
F. Palmieri, P. Gomis, J. E. Ruiz, D. Ferreira, E. Pueyo, J. P. Martínez, P. Laguna, J. Ramírez (2021) Weighted Time Warping T-wave Analysis Robust to Delineation Errors: Clinical Implications. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
C. Celotto, C. Sánchez, K. Mountris, P. Laguna, E. Pueyo (2021) Rotor Termination in Cholinergic Paroxysmal Atrial Fibrillation by Small-Conductance Calcium-Activated K+ Channels Inhibition and Isoproterenol: a Computational Study. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
R. Cebollada, C. Pérez, K. Mountris, J. P. Martínez, P. Laguna, E. Pueyo (2021). Mechanisms Underlying QT Interval Adaptation Behind Heart Rate During Stress Test. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
A. Martin, L. Sornmo, P. Laguna (2021) Multilead QT Interval Adaptation to Heart Rate Changes in Atrial Fibrillation: Dealing with the Presence of f-Waves. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
M. Butkuvien, A. Petrenas, A. Solosenko, A.Martin-Yebra, V. Marozas, L. Sornmo (2021) Atrial Fibrillation Episode Patterns and Their Influence on Detection Performance, Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
R. Rosales, K. Mountris, M. Doblaré, M. Mazo, E. Pueyo (2021) In silico Electrophysiological Evaluation of Scaffold Geometries for Cardiac Tissue Engineering. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
D. García, S. Kontaxis, A. Hernández-Vicente, D. Hernando, J. Milagro, E. Pueyo, N. Garatachea, R. Bailón, J. Lazaro (2021) Ventilatory Thresholds Estimation Based on ECG-derived Respiratory Rate. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
M. Pérez, L. García, K. Mountris, N. Smisdom, J. M Vallejo-Gil, P. C Fresneda-Roldán, J. Fañanás-Mastral, M. Matamala-Adell, M. Vázquez-Sancho, F. Javier Mancebón-Sierra, A. Sebastián Vaca-Núñez, C. Ballester-Cuenca, A. Olivan-Viguera, L. Ordovás, E. Pueyo (2021) Age-associated changes in fibrosis amount and spatial organization and its effects on human ventricular electrophysiology. Proceedings of the XLVII International Conference on Computing in Cardiology. Brno Czech Republic.
Laura García-Mendívil, Nick. Smisdom, Sam Duwe, Konstantinos Mountris, Sabarathinam Srinivasan, Marta Pérez, Lluís Luján, Esther Wolfs, Ronald B. Driesen, Aida Olivan-Viguera, José María Vallejo-Gil, Pedro Carlos Fresneda-Roldán, Javier Fañanás-Mastral, Manuel Vázquez-Sancho, Marta Matamala-Adell, Fernando Sorribas-Berjón, Carlos Ballester-Cuenca, Emiliano Diez, Laura Ordovás, Esther Pueyo (2021) Caracterización del remodelado cardiaco asociado a la edad en el ventrículo izquierdo humano. Primer congreso anual de estudiantes de doctorado de la Universidad Miguel Hernández. 2021. Comunicación oral
Laura García-Mendívil (/2021) Age-related cardiac remodeling in the human left ventricle. In vitro and in silico modeling. Ciclo de seminarios de investigadores predoctorales en Investigaciones Biomédicas Aragón. 2021. Comunicación oral
Laura García Mendívil, Natalia Hernández Bellido, Marcos Sánchez Barat, María Pérez Zabalza, Elisa Garrido Huéscar, Juan Carlos Oliveros, Rafael Torres Pérez, Estel Ramos Marquès, Esther Pueyo, Laura Ordovás. Envejecimiento cardiaco humano: transcriptómica y desarrollo de modelos celulares de envejecimiento. X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Chiara Celotto, Carlos Sánchez, Konstantinos A. Mountris, Pablo Laguna, Esther Pueyo (2021) Efectos Transitorios y en Estado Estacionario del Bloqueo del Canal SK y de la Estimulación Adrenérgica para Contrarrestar los Efectos Arritmogénicos Inducidos por Acetilcolina en la Aurícula Humana: un Estudio Computacional. X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Alba Pérez-Martínez , Aida Oliván-Viguera, Esther Pueyo (2021) Contribución de los canales SK a la electrofisiología ventricular humana en pacientes con insuficiencia cardíaca. X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Jennifer Riccio , Alejandro Alcaine, Juan Pablo Martínez , Pablo Laguna (2021) Análisis de dispersión de autovalores de electrogramas unipolares para la detección de fibrosis auricular. X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Hassaan A. Bukhari, Carlos Sánchez, Mark Potse, Pablo Laguna, Esther Pueyo (2021) Estimación del nivel de potasio en sangre mediante las pendientes del QRS del electrocardiograma en pacientes renales crónicos X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Ricardo Maximiliano Rosales, Konstantinos Mountris, Manuel Doblaré, Manuel Mazo, Esther Pueyo (2021) Evaluación Computacional de la Arquitectura de la Matriz de Cultivo en la Electrofisiología Cardíaca X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Cristina Pérez, Esther Pueyo, Juan Pablo Martínez, Pablo Laguna (2021) Mejora de la delineación del intervalo QT en señales ECG grabadas durante prueba de esfuerzo X Jornada de Jóvenes Investigadores I3A. Comunicación oral
Laura García Mendívil, Natalia Hernández Bellido, Marcos Sánchez Barat, María Pérez Zabalza, Elisa Garrido Huéscar, Juan Carlos Oliveros, Rafael Torres Pérez, Estel Ramos Marquès, Esther Pueyo, Laura Ordovás (2021). In vivo and in vitro cardiac aging: developing of cellular aging models. XIX Congreso de la Sociedad Española de Biología Celular. Póster

Ph.D. Thesis

Alberto Hernando Sanz (2021), Characterization of the Autonomic Nervous System Response in Hyperbaric Environments. Universidad de Zaragoza

Patents

2020

Journals and Books

F. J. Sánchez, V. A. Gonzalez, M. Farrando, A.l O. Baigorria Jayat, M. Segovia-Roldan , L. García-Mendívil, L. Ordovás, N. J. Prado, E. Pueyo, E. R. Diez (2020) Atrial Dyssynchrony Measured by Strain Echocardiography as a Marker of Proarrhythmic Remodeling and Oxidative Stress in Cardiac Surgery Patients. Oxidative Medicine and Cellular Longevity, Article ID 8895078, doi: 10.1155/2020/8895078
Boon, R.; Kumar, M.; Tricot, T.; Elia, I.; Ordovas, L.; Jacobs, F.; One, J.; De Smedt, J.; Eelen, G.; Bird, M.; Roelandt, P.; Doglioni, G.; Vriens, K.; Rossi, M.; Vazquez, M.A.; Vanwelden, T.; Chesnais, F.; El Taghdouini, A.; Najimi, M.; Sokal, E.; Cassiman, D.; Snoeys, J.; Monshouwer, M.; Hu, W.S.; Lange, C.; Carmeliet, P.; Fendt, S.M.; Verfaillie, C.M (2020). Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nature Communications DOI: 10.1038/s41467-020-15058-6
M. B. Hossain, S. K. Bashar, J. Lazaro, N. Reljin, Y. Noh, K. H. Chon (2020). A robust ECG denoising technique using variable frequency complex demodulation, Computer Methods and Programs in Biomedicine, doi: 10.1016/j.cmpb.2020.105856.
A. Oliván‑Viguera, M. Pérez‑Zabalza, L. García‑Mendívil, K.A. Mountris, S. Orós‑Rodrigo, E. Ramos‑Marquès, J.M. Vallejo‑Gil, P.C. Fresneda‑Roldán, J. Fañanás‑Mastral, M. Vázquez‑Sancho, M. Matamala‑Adell, F. Sorribas‑Berjón, J.A. Bellido‑Morales, F.J. Mancebón‑Sierra, A.S. Vaca‑Núñez, C. Ballester‑Cuenca, M.A. Marigil, C. Pastor, L. Ordovás, R. Köhler, E. Diez, E. Pueyo (2020). Minimally invasive system to reliably characterize ventricular electrophysiology from living donors. Sci Rep. 10:19941 doi: 10.1038/s41598-020-77076-0.
V. S. Chauhan, J. P. Martínez, M.A. G. van der Heyden (2020). Commentary: Increased Beat-to-Beat Variability of T-Wave Heterogeneity Measured From Standard 12-Lead Electrocardiogram Is Associated With Sudden Cardiac Death: A Case-Control Study, 11:598314 doi: 10.3389/fphys.2020.598314.
A. Rodrigues, A. Petrenas, B. Paliakaite, N. Kušleikaite-Pere, G. Jaruševičius, I. A. Bumblyte, P. Laguna, V. Marozas (2020) Noninvasive Monitoring of Potassium Fluctuations During the Long Inter dialytic Interval. IEEE Access vol. 8, pp.188488-188502 doi:10.1109/ACCESS.2020.3031471
K.A. Mountris, E. Pueyo (2020). The Radial Point Interpolation Mixed Collocation Method (RPIMC) for the solution of transient diffusion problems. Eng Anal Bound Elem. vol. 121 pp. doi: 207–216. 10.1016/j.enganabound.2020.10.005
J. Behar, C. Liu, Y. Zigel, P. Laguna, G. Clifford (2020) Editorial on remote health monitoring: from chronic diseases to pandemics. Physiological Measurement. 41, 100401 doi: 10.1088/1361-6579/abbb6d
A. Oliver-Gelabert, L. García-Mendívil, J.M. Vallejo-Gil, P. C. Fresneda-Roldán, K. Andelová, J. Fañanás-Mastral, M. Vázquez-Sancho, M. Matamala-Adell, F. Sorribas-Berjón, C. Ballester-Cuenca, N. Tribulova, L. Ordovás, E.R. Diez, E. Pueyo (2020). Automatic quantification of cardiomyocyte dimensions and connexin 43 lateralization in fluorescence images. Biomolecules. 2020, 10(9), 1334; https://doi.org/10.3390/biom10091334
A. Hernández-Vicente, D. Hernando, A. Santos-Lozano, G. Rodríguez-Romo, G. Vicente-Rodríguez, E. Pueyo, R. Bailón, N. Garatachea. (2020) Heart rate variability and exceptional longevity", Frontiers in Physiology, doi: 10.3389/fphys.2020.566399.
N. Reljin, J. Lazaro, M. B. Hossain, Y. S. Noh, C. H. Cho, and K. H. Chon (2020) Using the Redundant Convolutional Encoder–Decoder to Denoise QRS Complexes in ECG Signals Recorded with an Armband Wearable Device. Sensors, 20(16), 4611, DOI: 10.3390/s20164611
P. P. Nanasi, E. Pueyo and L. Virag (2020) Editorial: Perspectives of Antiarrhythmic Drug Therapy: Disappointing Past, Current Efforts, and Faint Hopes, Frontiers in Pharmacology, doi: 10.3389/fphar.2020.01116
A. Calleja-Romero, I. López-Laval, S. Sitko, D. Hernando, G. Vicente-Rodríguez, R. Bailón, N. Garatachea (2020) Effects of a 75Km mountain ultra-marathon on heart rate variability in amateur runners. The Journal of Sports Medicine and Physical Fitness vol. 60 n.10 pp. 1401-7, doi: 10.23736/S0022-4707.20.10860-0
R. Barrio, M.A. Martínez, L. Pérez, E. Pueyo (2020). Bifurcations and slow-fast analysis in a cardiac cell model for investigation of early afterdepolarizations. Mathematics, 8(6), 880, DOI: 10.3390/math8060880.
R Barrio, S Coombes, M Desroches, F Fenton, S Luther, E Pueyo (2020) Excitable Dynamics in Neural and Cardiac Systems. Communications in Nonlinear Science and Numerical Simulation, 105275 Commun 86 105275
doi.org/10.1016/j.cnsns.2020.105275
J. Lázaro, N. Reljin, M-B. Hossain, Y. Noh, P. Laguna, K. H. Chon, (20220) Wearable Armband Device for Daily Life Electrocardiogram Monitoring. IEEE Transactions Biomedical Engineering. Vol. 67, n.. 12, pp. 3464--3473 doi: 10.1109/TBME.2020.2987759
N. J. Prado, M. Segovia-Roldan, E. R. Diez, E. Pueyo (2020), Book: Melatonin; Chapter: Melatonin for a Healthy Heart Rhythm. IntechOpen. doi: 10.5772/intechopen.91447.
J. Lozano-Gerona, A. Oliva´n-VigueraID, P. Delgado-Wicke, V. Singh, B. M. Brown, E. Tapia-Casellas, E. Pueyo, M. Sofía Valero, A. L. Garcia-Otín, P. Giraldo, E. Abarca-Lachen, J. C. Surra, J. Osada, K. L. Hamilton, S.P. Raychaudhuri, M. Marigil, A. Juarranz, H. Wulff, H. Miura, Y. Gilaberte, R. Köhler (2020) Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis, PlosOne, E 15(3): e0222619. pp:1-18, doi: 10.1371/journal.pone.0222619.
A Alcaine, B. Jáuregui, D. Soto-Iglesias, J. Acosta, D. Penela, J. Fernández-Armenta, M. Linhart, D. Andreu, L. Mont, P. Laguna, O. Camara, J. P. Martínez A. Berruezo (2020) Automatic Detection of Slow Conducting Channels during Substrate Ablation of Scar-related Ventricular Arrhythmias. Journal of Interventional Cardiology, Vol. 2020, Article ID 4386841, 13 pages doi:10.1155/2020/4386841
C. Varon, J. Morales, J. Lázaro, M. Orini, M. Deviaene, S. Kontaxis, D. Testelmans, B Buyse, P. Borzée, L. Sörnmo, P. Laguna, E. Gil, and R. Bailón (2020). A Comparative Study of ECG-derived Respiration in Ambulatory Monitoring using the Single-lead ECG. Scientific reports, 10:5704. pp.1-14 doi: 10.1038/s41598-020-62624-5
M. Nardelli, G. Valenza, A. Greco, A. Lanata, E. P. Scilingo, R. Bailón, (2020) Quantifying the lagged Poincaré plot geometry of ultrashort heart rate variability series: automatic recognition of odor hedonic tone, Medical & Biological Engineering & Computing pp.1-14; doi: 10.1007/s11517-019-02095-7
N. J. Prado, E. M. Muñoz, L. E. Farias-Altamirano, F. Aguiar, A. Z. Ponce-Zumino, F. J. Sánchez, R. M. Miatello, E. Pueyo*, E. R. Diez, (2020), Reperfusion Arrhythmias Increase After Superior Cervical Ganglionectomy Due To Conduction Disorders And Changes In Repolarisation. International Journal of Molecular Sciences, 21(5), pp. 1804, DOI: 10.3390/ijms21051804 .
J. Corral-Acero, F. Margara, M. Marciniak, C. Rodero, F. Loncaric, Y. Feng, A. Gilbert, J. F Fernandes, H. A Bukhari, A. Wajdan, M. Villegas-Martinez, M. Sousa-Santos, M. Shamohammdi, H. Luo, P. Westphal, P. Leeson, P. DiAchille, V. Gurev, M. Mayr, L. Geris, P. Pathmanathan, T. Morrison, R. Cornelussen, F. Prinzen, T. Delhaas, A. Doltra, M. Sitges, E. J Vigmond, E. Zacur, V. Grau, B. Rodriguez, E.W Remme, S. Niederer, P. Mortier, K. McLeod, M. Potse, E. Pueyo, A. Bueno-Orovio, P. Lamata (2020), The 'Digital Twin' to enable the vision of precision cardiology. European Heart Journal, ehaa159, doi: 10.1093/eurheartj/ehaa159.
S. van Duijvenboden, B. Porter, E. Pueyo, D. A. Sampedro-Puente, J. Fernandez-Bes, B. Sidhu, J. Gould, M. Orini, M. Bishop, B. Hanson, P. Lambiase, R. Razavi, C. A. Rinaldi, J. S. Gill and P. Taggart (2020) Complex interaction between low-frequency APD oscillations and beat-to-beat APD variability in humans is governed by the sympathetic nervous system, Front. Physiol. 10:1582. doi: 10.3389/fphys.2019.01582
D. A. Sampedro-Puente, J. Fernandez-Bes, N. Szentandrássy, P. Nánási, P. Taggart and E. Pueyo (2020). Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis. Front. Physiol. 10:1547. doi: 10.3389/fphys.2019.01547
S. Kontaxis, J. Lázaro, V. D. A. Corino, F. Sandberg, R. Bailón, P. Laguna, and L. Sörnmo, (2020) ECG-derived Respiratory Rate in Atrial Fibrillation. IEEE Transactions Biomedical Engineering. vol. 67, n. 3, pp. 905--914 doi: 10.1109/TBME.2019.2923587
D. A. Sampedro-Puente; J. Fernandez Bes; L. Virág; A. Varró; E. Pueyo (2020) Data-driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-beat Variability. IEEE Journal of Biomedical and Health Informatics, vol. 24, issue 3, pp. 693-704. DOI 10.1109/JBHI.2019.2921881,
J. Milagro, J. Gracia, V.P. Seppä, J. Karjalainen, M. Paassilta, M. Orini, R. Bailón, E. Gil, J. Viik (2020) Noninvasive Cardiorespiratory Signals Analysis for Asthma Evolution Monitoring in Preschool Children. IEEE Transactions Biomedical Engineering. vol. 67, n. 7, pp. 1863-1871, doi: 10.1109/TBME.2019.2949873
J. Milagro, D. Hernando, J. Lazaro, J. A. Casajus, N. Garatachea, E. Gil and R. Bailón (2020) Electrocardiogram-Derived Tidal Volume During Treadmill Stress Test, IEEE Transactions Biomedical Engineering. vol. 67, n. 1, doi: 10.1109/TBME.2019.2911351
K.A. Mountris, GC. Bourantas, D. Millán, R. Joldes, K. Miller, E. Pueyo, A. Wittek (2019) Cell-based maximum entropy approximants for three-dimensional domains: Application in large strain elastodynamics using the meshless total Lagrangian explicit dynamics method. Int J Numer Methods Eng. 2020;121:477–491. doi: 10.1002/nme.6218

Conference Proceedings

Martinez, C., Kontaxis, S., Posadas-de Miguel, M., Garcia, E., Siddi, S., Bernal, M. L., Aguilo, J., Haro, J. M., Bailon, R, Ortega, A (2020). Analysis of prosodic features during cognitive load in patients with depression. 11th International Workshop on Spoken Dialog System Technology, Spain, 2020
J. Lázaro, N. Reljin, R. Bailon, E. Gil, Y. Sik Noh, P. Laguna, K. Chon (2020) Electrocardiogram Derived Respiration for Tracking Changes in Tidal Volume from a Wearable Armband. 42st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). doi: 10.1109/EMBC44109.2020.9175486
C. Celotto, C. Sanchez, K. Mountris, P. Laguna, E. Pueyo (2020). SK Channel Block and Adrenergic Stimulation Counteract Acetylcholine-Induced Arrhythmogenic Effects in Human Atria. 42st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). doi: 10.1109/EMBC44109.2020.9175886
G. Luongo, L. Azzolin, J. P. Martínez, P. Laguna, O. Doessel, A. Loewe, R. Sassi, M. W. Rivolta (2020). Non-Invasive Identification of Atrial Fibrillation Driver Location Using the 12-lead ECG: Pulmonary Vein Rotors vs. other Locations. 42st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). doi: 10.1109/EMBC44109.2020.9176135
C. Pérez, E. Pueyo, J. P. Martínez, P. Laguna (2020) Characterization of impaired repolarization by quantification of the QT delay in response to heart rate changes from stress test recordings. 11th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO). doi: 10.1109/ESGCO49734.2020.9158186
J. Riccio, A. Alcaine, S. Rocher,P. Laguna, J. Saiz, J. P. Martinez (2020) Omnipolar EGM Voltage Mapping for Atrial Fibrosis Identiﬁcation Evaluated with an Electrophysiological Model. 28-th Conference (EUSIPCO), Amsterdam, Holland. pp. 920-924
C. Sánchez, A. Hernando, J. Bolea, D. Izquierdo, M. T. Lozano Albalate, M. D. Peláez Coca. (2020). Safety Ranges for Heart Rate Variability Parameters in Hyperbaric Environments. Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy. pp. 1-4 doi:10.22489/CinC.2020.094
A. Hernando, M. D. Peláez Coca, C. Sánchez, J. Bolea, D. Izquierdo, M. T. Lozano Albalate, E. Gil (2020). Autonomic Nervous System Response During Scuba Diving Activity. Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.308
S. Kontaxis, P. Laguna, E. García, M. Posadas-de Miguel, S. Siddi, M. L. Bernal, J. M. Haro, J. Aguiló, C. de la Camara, R. Bailón, E. Gil. (2020) Blunted Autonomic Reactivity to Mental Stress in Depression Quantified by Nonlinear Cardiorespiratory Coupling Indices, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4, doi:10.22489/CinC.2020.233
C. Pérez, E. Pueyo, J. P. Martínez, J. Viik, P. Laguna (2020) Characterization of Impaired Ventricular Repolarization by Quantification of QT Delayed Response to Heart Rate Changes in Stress Test, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4; doi: 10.22489/CinC.2020.194
D. A. Sampedro-Puente, F. Raphel, J. Fernandez-Bes, P. Laguna, D. Lombardi, E. Pueyo (2020) In Silico Characterization of Repolarization Duration and Variability in the Long QT1 Syndrome Under β-Adrenergic Stimulatio, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.430
J. Lazaro, N. Reljin, R. Bailón, E. Gil, Y. Noh, P. Laguna, K. Chon (2020) An ECG-based System for Respiratory Rate Estimation Tested on a Wearable Armband During Daily Life, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.251
G. Luongo, L. Azzolin, M. W Rivolta, T. Paggi de Almeida, J. P. Martínez, D. Coutinho Soriano, O. Doessel, R. Sassi, P. Laguna, Axel Loewe (2020) Machine Learning to Find Areas of Rotors Sustaining Atrial Fibrillation from the ECG (P) Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4, doi:10.22489/CinC.2020.181
S. Srinivasan*, S.H. A. Bukhari, P. Laguna, C. Sánchez, E. Pueyo (2020) Analysis of T Wave Nonlinear Dynamics for Serum Potassium Monitoring in End-Stage Renal Disease Patients, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.461
C. Celotto, C. Sánchez, K. Mountris, M. Abdollahpur, F. Sandberg, P. Laguna, E. Pueyo (2020) Relationship Between Atrial Oscillatory Acetylcholine Release Pattern andf-wave Frequency Modulation: a Computational and Experimental Study, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.303
J. Riccio, S. Rocher, L. Martinez, A. Alcaine, J. Saiz, J. P. Martínez, P. Laguna (2020) Unipolar Electrogram Eigenvalue Distribution Analysis for the Identification of Atrial Fibrosis, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4, doi:10.22489/CinC.2020.434
F. L Bueno-Palomeque, K. Mountris, A. Minchole, N. Ortigosa, E. Pueyo, P. Laguna (2020) Changes in QRS and T-wave Loops Subsequent to an Increase in Left Ventricle Globularity as in Intrauterine Growth Restriction: a Simulation Study, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.438
J. Milagro, M. Martínez, S. Kontaxis, D. Hernando, E. Gil, R. Bailón, I. Salinas, C. Heras, P. Laguna (2020) In Bed Contactless Cardiorespiratory Signals Monitoring Using Optical Fiber Interferometry, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp.1-4 doi:10.22489/CinC.2020.051
S. Kontaxis, A. Martin, A. Petrenas, V. Marozas, R. Bailón, P. Laguna, L. Sornmo (2020) Investigating Respiratory Rate Estimation During Paroxysmal Atrial Fibrillation Using an Improved ECG Simulation Model, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.239
F. Palmieri, P. Gomis, J. E. Ruiz, D. Ferreira, A. Martin, E. Pueyo, P. Laguna, J. P. Martínez, J. Ramírez (2020) Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic versus Principal Component Analysis, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4, doi:10.22489/CinC.2020.199
P. Armañac, D. Hernando, J. Lazaro, C. de Haro, R. Magrans, L. Sarlabous, J. López-Aguilar, P. Laguna, E. Gil, L. Blanch, R. Bailón (2020) Baroreflex Sensitivity Evolution before Weaning From Mechanical Ventilation, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.235
S. Palacios, J. P. Martínez, E. Pueyo (2020) Sudden Cardiac Death Prediction in Chronic Heart Failure Patients by Periodic Repolarization Dynamics, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.209
M. Pérez-Zabalza, E. R. Diez, J. Rhyins, K. Mountris, M. Segovia-Roldán, A. Oliván-Viguera, E. Pueyo (2020) Improved methods for processing optical mapping signals from human left ventricular tissues at baseline and following adrenergic stimulation, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.427
K. Mountris, E. Pueyo (2020) Next-generation in-silico Cardiac Electrophysiology through Immersed Grid Meshfree Modelling. Application to Simulation of Myocardial Infarction, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.254
J. Morales, P. Borzee, D. Testelmans, B. Buyse, S. van Huffel, R. Bailón, C. Varon (2020) A Robust Estimator of the Cardiorespiratory Coupling, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.093
D. Cajal, D. Hernando, J. Lazaro, E. Gil, A. Alvis, M. Polcz, K. Hocking, C. Brophy, R. Bailón (2020) Parasympathetic Characterization Guided by Respiration from Wrist Peripheral Venous Pressure Waveform, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.415
D. Romero, J. Lazaro, R. Jané, P. Laguna, R. Bailón (2020) A Quaternion-based Approach to Estimate Respiratory Rate from the Vectorcardiogram, Proceedings of the XLVII International Conference on Computing in Cardiology. Rimini, Italy, pp. 1-4 doi:10.22489/CinC.2020.382
K. Mountris, E. Pueyo, (2020). The Radial Point Interpolation Mixed Collocation (RPIMC) Method For The Solution Of The Reaction-Diffusion Equation In Cardiac Electrophysiology. Proceedings of the International Conference on Computational & Experimental Engineering and Sciences,
S. Palacios, I. Cygankiewicz, A. Bayés-de-Luna, J.P. Martínez, E. Pueyo (2020) Predicción de muerte súbita en pacientes con insuficiencia cardíaca crónica mediante el estudio de la dinámica periódica de la repolarización. XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Valladolid, España. pp. 10-13,
F. Palmieri, P. Gomis, J.E. Ruiz, D. Ferreira, A. Martín-Yebra, E. Pueyo, P. Laguna, J.P. Martínez, J. Ramírez, (2020) Monitorización en diálisis de la Concentración de Potasio en Sangre mediante los cambios en la morfología multi-lead de la onda T: Comparación Entre usar la transformación en Componentes Periódicas y Principales. XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Valladolid, España. pp. 434-437,
D.A. Sampedro-Puente, F. Raphel, J. Fernandez-Bes, P. Laguna, D. Lombardi, E. Pueyo (2020) Caracterización in silico de la duración de la repolarización y su variabilidad en el síndrome de QT Largo Tipo1 bajo estimulación β adrenérgica, XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Valladolid, España, pp. 344- 347
M. Martinez, J. Lazaro, S. Kontaxis, P. Laguna, E. Gil, M.L. Bernal Ruíz, S. Siddi, C. de la
Cámara, J. Aguiló, E. García, J.M. Haro. R. Bailón (2020). Análisis de la respuesta electrodermal para la identificación de pacientes con depresión, XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Valladolid, España, pp. 256- 259
C. Pérez Martínez, E. Pueyo Paules, JP. Martínez Cortés, J. Viik, P. Laguna (2020). Retardo entre QT y RR en registros de prueba de esfuerzo como indicador de la heterogeneidad de la repolarización ventricular, XXXVIII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Valladolid, España, pp. 6- 9

Ph.D. Thesis

D. Sampedro (2020) Theoretical analysis of autonomic nervous system effects on cardiac electrophysiology and its relationship with arrhythmic risk. Universidad de Zaragoza
S. Kontaxis (2020) Autonomic nervous system biomarkers from multi-modal and model-based signal processing in mental health and illness. Universidad de Zaragoza

Patents

2019

Journals and Books

M. S. Valero, M. Ramón-Gimenez, J. Lozano-Gerona, P. Delgado-Wicke, P. Calmarza, A. Oliván-Viguera, V. López, Á.L. Garcia-Otín, S. Valero, E. Pueyo, K. L. Hamilton, H. Miura and R. Köhler, (2019). KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility, International Journal of Molecular Sciences, vol. 20, n. 1193; doi:10.3390/ijms20051193
D. A. Sampedro-Puente, J. Fernández-Bes, N. Szentandrássy, P. Nánasi, E. Pueyo. (2019) Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis. Front. Physiol. | doi: 10.3389/fphys.2019.01547
S Palacios, E. G. Caiani, F. Landreani, J. P. Martínez, E. Pueyo (2019) Long-term microgravity exposure increases ECG repolarization instability manifested by low-frequency oscillations of T-wave vector. Frontiers in Physiology; . 10:1510 doi: 10.3389/fphys.2019.01510
M. Orini, F. Al-Amodi, S. Koelsch, R. Bailón (2019). The Effect of Emotional Valence on Ventricular Repolarization Dynamics Is Mediated by Heart Rate Variability: A Study of QT Variability and Music-Induced Emotions. Frontiers in Physiology, 10:1465, doi: 10.3389/fphys.2019.01465
M. Llamedo, J.P. Martínez (2109) Assessment of automatic strategies for combining QRS detections by multiple algorithms in multiple leads. Physiological Measurement, doi: 10.1088/1361-6579/ab553a
A. Martín-Yebra, V. Monasterio, F. Landreani, P. Laguna, J. P. Martínez, E. G. Caiani (2019) Assessment of ventricular repolarization instability in terms of T-wave alternans induced by head-down bed-rest immobilization. Physiological Measurement, vol. 40. 104001 (9pp) doi: 10.1088/1361-6579/ab4c18
J. Ramírez, S. Van Duijvenboden, N. Aung, P. Laguna, E. Pueyo, A. Tinker, P. Lambiase, M. Orini, P. Munroe (2019), The Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics. Circ Arrhythm Electrophysiol;12:e007549. DOI: 10.1161/CIRCEP.119.007549
A. Hernando, M.D. Peláez Coca, M.T. Lozano, J. Lázaro, E. Gil (2019). Finger and forehead PPG signal comparison for respiratory rate estimation, Physiological Measurement, v. 40. 095007 (12pp) doi: 10.1088/1361-6579/ab3be0
L. Iozzia, J. Lazaro, L. Cerina, D. Silvestri, L. Mainardi, P. Laguna, E. Gil, (2019) Monitoring breathing rate by fusing the physiological impact of respiration on video-photoplethysmogram with head movements, Physiological Measurement, vol. 40. 094002 (12pp) doi: 10.1088/1361-6579/ab4102
D. A. Sampedro-Puente, J. Fernandez-Bes, B. Porter, S. Duijvenboden, P. Taggart E. Pueyo (2019), Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat variability of celullar ventricular repolarization in response to sympathetic stimulation: Implications for arrhythmogenesis. Frontiers in Physiology. Vol. 10, | Article 916, pp.1-18, doi: 10.3389/fphys.2019.00916
M.T. Valderas, J.Bolea, P. Laguna, R. Bailón, M. Vallverdu (2019) Mutual information between heart rate variability and respiration for emotion characterization", Physiological Measurement, vol. 40, 084001, 15pp, doi: 10.1088/1361-6579/ab310a
J. Milagro, M. Deviaene, E. Gil1, J. Lazaro, B. Buyse, D. Testelmans, P. Borzee, R. Willems, S. Van Huffel, R. Bailon, C. Varon (2019) Autonomic Dysfunction Increases Cardiovascular Risk in the Presence of Sleep Apnea, Front. Physiolog. vol.10 n. 620 pp. 1-11, DOI: 10.3389/fphys.2019.00620
J. Lázaro, E. Gil, M. Orini, P. Laguna, and R. Bailón (2019) Baroreflex Sensitivity Measured by Pulse Photoplethysmography, Front. Neurosci. 13:339. pp.1-13, doi: 10.3389/fnins.2019.00339
A. Martín-Yebra, and J. P. Martínez (2019)Automatic diagnosis of strict left bundle branch block using a wavelet-based approach. Plos One, 14(2): e0212971. pp. 1-11; doi:10.1371/journal.pone.0212971
E. Peralta, J. Lazaro, R. Bailón, V. Marozas and E. Gil (2019) Optimal Fiducial Points for Pulse Rate Variability Analysis from Forehead and Finger PPG Signals, Physiological Measurement, 40, 025007 (15pp) doi: 10.1088/1361-6579/ab009b
M. T. Valderas, J. Bolea, M. Orini, P. Laguna, C. Orrite, M.Vallverdu, R. Bailón (2019) Human emotion characterization by heart rate variability analysis guided by respiration, IEEE Journal of Biomedical and Health Informatics, vol. 23, n. 6, pp. 2446-2454 doi: 10.1109/JBHI.2019.2895589
C. Varon, J. Lázaro, J. Bolea, A. Hernando, J. Aguiló, E. Gil, S. Van Huffel, R. Bailón. (2019) Unconstrained Estimation of HRV Indices after Removing Respiratory Influences from Heart Rate, IEEE Journal of Biomedical and Health Informatics, vol. 23, n. 6, pp. 2386- 2397, doi: 10.1109/JBHI.2018.2884644
M. Peláez, M. T. Lozano, A. Hernando, M. Aiger, E. Gil (2019). Photoplethysmographic Waveform Versus Heart Rate Variability to Identify Low Stress States. Attention Test. IEEE Journal of Biomedical and Health Informatics, vol. 23, n. 5, pp. 1940-1951 doi:10.1109/JBHI.2018.2882142,
A. Martín-Yebra, P. Laguna, I. Cygankiewicz, A. Bayés-de-Luna, E. G. Caiani, J. P. Martínez (2019) Quantification of Ventricular Repolarization Variation for Sudden Cardiac Death Risk Stratification in Atrial Fibrillation. IEEE J Biomed Health Inform, v.. 23, n. 3, pp 1049-1057. doi: 10.1109/JBHI.2018.2851299
A. Arza, J. M. Garzón-Rey, J. Lázaro, E. Gil1, R. Lopez-Anton, C. de la Camara, P. Laguna, R. Bailon, J. Aguiló (2019) Measuring acute stress response through physiological signals: Towards a quantitative assessment of stress. Medical & Biological Engineering & Computing. vol. 57, pp. 271–287 doi: 10.1007/s11517-018-1879-z
A. Hernando, M. D. Peláez-Coca, M. T. Lozano, M. Aiger, David Izquierdo, A. Sánchez, M. I. López-Jurado, I. Moura, J. Fidalgo, J. Lázaro, E. Gil (2019), Autonomic nervous system measurement in hyperbaric environments using ECG and PPG signals. IEEE J Biomed Health Inform, vol. 23, n. 1, pp. 132-142. doi: 10.1109/JBHI.2018.2797982
D. Luengo, G. Ríos-Muñoz, V. Elvira, C. Sánchez, A. Artés (2019). “Hierarchical Algorithms for Causality Retrieval in Atrial Fibrillation Intracavitary Electrograms”. IEEE J Biomed Health Inform, vol. 23, n. 1, pp. 143-155. doi: 10.1109/JBHI.2018.2805773
S. Kontaxis, J. Lázaro, E. Gil, P. Laguna, R. Bailón (2019) Assessment of Quadratic Nonlinear Cardiorespiratory Couplings During Tilt Table Test by Means of Real Wavelet Biphase, IEEE Transactions Biomedical Engineering. vol. 66, n. 1, pp. 187-198 doi: 10.1109/TBME.2018.2821182

Conference Proceedings

E. Ramos, L. García, JC. Oliveros, R. Torres, A. López, A. Olivan, JM. Vallejo, P.C.. Fresneda, J. Fañanás, M. Matamala, F. Sorribas, M. Vázquez, C. Ballester, L. Ordovás, E. Pueyo (2019). The role of microRNAs in age-related remodeling of the human left ventricle. Poster, European Society of Cardiology (ESC)
L. García, N. Smisdom, KA. Mountris, A. Olivan, JM. Vallejo, PC. Fresneda, J. Fañanás, M. Matamala, F. Sorribas, M. Vázquez, C. Ballester, E. Wolfs, RB Driesen, L. Ordovás, E. Pueyo (2019). Histological characterization of age-related remodeling in human left ventricle by second harmonic generation and lipofuscin content. Poster, European Society of Cardiology (ESC)
L. García, E Ramos, J. C. Oliveros, R. Torres, E. Pueyo, L. Ordovás (2019).Transcriptional analysis of human cardiac aging by chronological and biological age. European Society of Cardiology (ESC)
A. Hernandez, D. Hernando, D. Navarrete, G. Vicente, R. Bailón, E. Pueyo, N. Garatachea (2019) El nivel de condición física tiene un papel relevante ne la dinámica de la repolarización cardíaca. II Congreso Internacional en ciéncias de la salud y del deporte.
A. Hernández-Vicente, G. Rodríguez-Romo, D. Hernando, G. Vicente-Rodríguez, E. Pueyo, R. Bailón, N. Garatachea. (2019) La variabilidad de la frecuencia cardíaca como predictor de mortalidad a corto plazo en centenarios 61º Congreso de la Sociedad Española de Geriatría y Gerontología / 26º Congreso de la Sociedad Aragonesa de Geriatría y Gerontología, 2019.
M. Llamedo, J.P. Martínez (2019). A Lead Selection Strategy based on an Estimated Detection Quality Index. XVIII Reunión de trabajo en Procesamiento de la Información y Control/XVIII Workshop on Information Processing and Control. Bahía Blanca (Argentina).
P. Sampaio, A. Leite, L. Pereira, J. P. Martínez, J. Vasconcelos (2019). Heart rate variability study in young subjects under stress conditions. 6th IEEE Portuguese meeting in Bioengineering. Lisboa (Portugal).
J. Milagro, J. Gracia, V-P Seppä, J. Karjalainen, M. Paassilta, M. Orini, E. Gil, R. Bailón, J. Viik, (2019) Cardiorespiratory Coupling in Asthmatic Children . Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
P. Armañac, S. Kontaxis, J. Lazaro, P. Laguna, R. Bailón, E. Gil (2019) Cardiovascular Changes Induced by Acute Emotional Stress Estimated from the Pulse Transit Time Difference. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
J. Lazaro, N. Reljin, Y. Noh, P. Laguna, K. Chon (2019) Heart Rate Variability Monitoring Using a Wearable Armband. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
S. Kontaxis, R. Bailón, A. Rapalis, M. Brazaitis, M. Cernych, J. Lazaro, P. Laguna, E. Gil, V. Maroza (2019) Autonomic Nervous System Response to Heat Stress Exposure by Means of Heart Rate Variability. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
S. H. A. Bukhari, F. Palmieri, D. Ferreira, M. Potse, J. Ramirez, P. Laguna, C. Sanchez, E. Pueyo (2019) Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Serum Potassium Levels. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
J. Riccio, A. Alcaine, N. de Groot, R. Houben, P. Laguna, J. P. Martínez (2019) Characterization of Propagation Patterns with Omnipolar EGM in Epicardial Multi-electrode Arrays. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
M. Rinkevicius, S. Kontaxis, E. Gil, R. Bailón, J. Lazaro, P. Laguna, V. Marozas (2019) PPG Signal Morphology-Based Stress Assessment Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
J. Milagro, L. Soto, J. Giner, C. Varon, P. Laguna, V. Plaza, E. Gil, R. Bailón (2019) Heart Rate Variability Analysis Assessment for Asthma Control Stratification. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
C. Varon, D. Hendrikx, J. Bolea, P. Laguna, R. Bailón (2019) Quantification of Linear and Nonlinear Cardiorespiratory Interactions under Autonomic Nervous System Blockade. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
C. Celotto, C. Sánchez, P. Laguna, E. Pueyo (2109) Calcium-Activated Potassium Channel Inhibition in Autonomically Stimulated Human Atrial Myocytes. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
F. Palmieri, P. Gomis, J. E. Ruiz, B. Bergasa, D. Ferreira, A. Martin, S. H. A. Bukhari, E. Pueyo, J. P. Martínez, J. Ramírez, P. Laguna (2019) T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
V. Monasterio, E. Pueyo, J. F. Rodríguez, J. Carro (2019) Influence of the Stimulation Current on the Differences between Cell and Tissue Electrophysiological Simulations. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
S. Palacios, E. Caiani, E. Pueyo, J. P. Martínez (2019) Response of Ventricular Repolarization to Simulated Microgravity Measured by Periodic Repolarization Dynamics Using Phase-Rectified Signal Averaging. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
K. Mountris, C. Sanchez, E. Pueyo (2019) A Novel Paradigm for in Silico Simulation of Cardiac Electrophysiology through the Mixed Collocation Meshless Petrov-Galerkin Method. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
J. Morales, J. Bolea, S. Van Huffel, R. Bailón, C. Varon (2019) Influence of the Heart Rate Variability Representations on the Quantification of the Cardiorespiratory Interactions. Proceedings of the XLVI International Conference on Computing in Cardiology. Singapore, pp. 1-4,
J. Lázaro ; N. Reljin ; Y. Noh ; P. Laguna ; K. H. Chon (2019) Feasibility of Long-Term Daily Life Electrocardiogram Monitoring Based on a Wearable Armband Device 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
D. Hernando; M. Nardelli; K. Hocking; J. Lázaro; B. Alvis; E. Gil; E. P. Scilingo; D. R. Brophy; G. Valenza; P. Laguna; C. Brophy; R. Bailón (2019) Effect of yoga on pulse rate variability measured from a venous pressure waveform. 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
J. F Morales ; M. Deviaene; J. Milagro, D. Testelmans, B. Buyse, R. Willems; M. Orini; S. Van Huffel, R. Bailon, C. Varon, (2019) Evaluation of Methods to Characterize the Change of the Respiratory Sinus Arrhythmia with Age in Sleep Apnea Patients. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
D. Han, J. Lázaro, E. Ding, C. Whitcomb, D. McManus and K. Chon. (2019) Smartwatch PPG Peak Detection Method for Sinus Rhythm and Cardiac Arrhythmia. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
M. D. Peláez, A. Hernando, C. Sánchez, M.T. Lozano; D. Izquierdo, E. Gil, (2019) Photoplethysmographic Waveform in Hyperbaric Environment. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
C. Pérez; M.D. Peláez; A. Hernando, E. Gil, C. Sánchez, (2019) Multivariable Relationships between Autonomic Nervous System Related Indices in Hyperbaric Environments. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
E. Pueyo (2019) Combined Experimental and Computational Research into Cardiac-Neural Interactions and Arrhythmias. Invited talk. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
P. Laguna (2019) Physiologically driven biomedical Signal processing: Making the most from signals. key note talk. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
R. Bailón (2019 Pitfalls and challenges of hrv analysis for emotion recognition. Invited work shop. 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).
F. Palmieri, P. Gomis, D. Ferreira, J.E. Ruiz, B. Bergasa, A. Martín-Yebra, H.A. Bukhari, E. Pueyo, J.P. Martínez, J. Ramírez, P. Laguna (2019) Estudio de los Cambios en la Morfología de las Ondas T como
Sustituto de la Concentración de Potasio en Sangre en Pacientes de Hemodiálisis XXXVII Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Santander, España. pp. 291–294.

Ph.D. Thesis

Jesus Carro (2019). New methodologies for the development and validation of electrophysiological models . Zaragoza University
Javier Milagro (2019), Noninvasive autonomic nervous system assessment in respiratory disorders and sport sciences applications Zaragoza University.
María Teresa Valderas Yamuza, (2019). Characterization of the autonomic nervous system response under emotional stimuli through linear and non-linear analysis of physiological signals. Universidad de Zaragoza/Universidad Politecnica de Cataluña

Patents

2018

Journals and Books

J. Bolea, R. Bailón and E. Pueyo (2018) On the standardization of approximate entropy: Multidimensional approximate entropy index evaluated on short- term HRV time series, Complexity, Article ID 4953273; pp. 1-15, doi.org/10.1155/2018/4953273
Monasterio V, Castro-Mur J, Carro J (2018) DENIS: Solving cardiac electrophysiological simulations with volunteer computing. PLOS ONE 13(10): e0205568, pp. 1-12;https://doi.org/10.1371/journal.pone.0205568
J. Carro, E. Pueyo, J. F. Rodríguez. (2018) A response surface optimization approach to adjust ionic current conductances of cardiac electrophysiological models. Application to the study of potassium level changes. PLOS One. pp. 1-23; doi:10.1371/journal.pone.0204411
E. Grandi, S. Morotti, E. Pueyo, B. Rodriguez (2018) Editorial: Safety Pharmacology – Risk Assessment QT Interval Prolongation and Beyond. Frontieres in Physiology, Vol. 9, Article 678, pp. 1-5 doi: 10.3389/fphys.2018.00678
D. Hernando, S. Roca, J. Sancho, Á. Alesanco, R. Bailón (2018) Validation of the AppleWatch for heart rate variability measurements during relax and mental stress in healthy subjects. Sensors, vol. 18, n. 2619, pp. 1-11, doi: 10.3390/s18082619
A. Rapalis, A. Petrénas, M. Šimaityté1, R. Bailón, V. Marozas (2018) Towards pulse rate parametrization during freeliving activities using smart wristband. Physiol. Meas. vol. 39 055007 (12pp). doi: 10.1088/1361-6579/aac24a
A. Hernández-Vicente, A. Santos-Lozano, R. Bailón, C. Mayolas-Pi, P. J. Marín, N. Garatachea. (2018) Effects of the type of exercise performed on the vibration delivered during whole-body vibration exercises. Journal of Vibroengineering, Volume 20, Issue 3 pp. 1522- 1529. doi: 10.21595/jve.2018.19622
A. Lyon, R. Ariga, A. Minchole, M. Mahmod, E. Ormondroyd, P. Laguna, N. de Freitas, S. Neubauer, H. Watkins, B. Rodriguez (2018). Distinct ECG phenotypes identified in hypertrophic cardiomyopathy using machine learning associate with arrhythmic risk markers. Frontiers in Physiology; vol. 1, ar. 213, pp, 1-13, doi: 10.3389/fphys.2018.00213
A. Martín-Yebra, V. Monasterio, I. Cygankiewicz, A. Bayés de Luna, E. G. Caiani, P. Laguna and J. P. Martínez (2018). Post-ventricular premature contraction phase correction improves the predictive value of average T-wave alternans in ambulatory ECG recordings. IEEE Transactions Biomedical Engineering. vol. 65, n. 3, pp. 635--644 doi: 10.1109/TBME.2017.2711645
P. Laguna; A. Garde, B. F Giraldo, O. Meste, R. Jané, L. Sörnmo, (2018) Eigenvalue-Based Time Delay Estimation of Repetitive Biomedical Signals. Digital Signal Processing, vol. 75, pp. 107–119 doi: 10.1016/j.dsp.2018.01.007
A Lyon, A Mincholé, J. P. Martínez, P. Laguna, B. Rodriguez (2018) Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances. Journal of the Royal Society: Interface.vol. 15, doi: 10.1098/rsif.2017.0821.
M. Holmer; J. P. Martínez; E. Gil; F. Sandberg; B. Olde; L. Sörnmo (2018) Detection of Ventricular Premature Beats Based on the Pressure Signals of a Hemodialysis Machine. Medical Engineering & Physics. v.51, pp.49–55 doi: 10.1016/j.medengphy.2017.11.004
A. Olivan-Viguera, A.L. Garcia-Otin, J. Lozano-Gerona, E. Abarca-Lachen, A.J. Garcia-Malinis, K.L Hamilton, Y. Gilaberte , E. Pueyo, R. Kohler (2018) Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes, PlosOne vol. 13, n. 1, e0190307, pp. 1--19, doi: 10.1371/journal.pone.0190307
J. Milagro, E. Gil, J. Lázaro, V.-P. Seppä, L. P. Malmberg, A. S. Pelkonen, A. Kotaniemi-Syrjänen, M. J. Mäkelä, J. Viik and R. Bailón (2018) , Nocturnal Heart Rate Variability Spectrum Characterization in Preschool Children with Asthmatic Symptoms, IEEE Journal of biomedical and health informatics, vol. 22, n. 5, pp. 1332-1340, doi: 10.1109/JBHI.2017.2775059
M. Orini, E. Pueyo, P. Laguna, R. Bailón (2018) A Time-Varying Non-Parametric Methodology for Assessing Changes in QT Variability Unrelated to Heart Rate Variability. IEEE Transactions Biomedical Engineering. v. 65, n. 7, pp. 1443- 1451 doi: 10.1109/TBME.2017.2758925
M. Nardelli, A.Greco, J.Bolea, G. Valenza, E.P. Scilingo, R.Bailón (2018). Reliability of Lagged Poincaré Plot parameters in ultra-short Heart Rate Variability series: Application on Affective Sounds. IEEE Journal of Biomedical and Health Informatics. vol. 22, n. 3, pp. 741-749, doi: 10.1109/JBHI.2017.2694999.
A. Alcaine, D. Soto-Iglesias, J. Acosta, V. Korshunov,D. Penela, M. Martínez, M. Linhart, D. Andreu, J. Fernández-Armenta, P. Laguna, J. P. Martínez, O. Camara, A. Berruezo, (2018) Automatic Activation Mapping and Origin Identification of Idiopathic Outflow Tract Ventricular Arrhythmias. Journal of Electrocardiology. vol. 51 pp. 239--246, doi: 10.1016/j.jelectrocard.2017.10.015
D. Hernando, A. Hernando, J. A. Casajús, P. Laguna, N. Garatachea, R. Bailón (2018). Methodological Framework for Heart Rate Variability Analysis During Exercise: Application to Running and Cycling Stress Testing. Medical & Biological Engineering & Computing, vol. 56, pp. 781-794, doi:10.1007/s11517-017-1724-9
C. Sanchez, G. D’Ambrosio. F. Maffessanti, E. G. Caiani, F. W. Prinzen, R. Krause, A. Auricchio, M. Potse (2018) Sensitivity analysis of ventricular activation and electrocardiogram in tailored models of heart-failure patients, Med Biol Eng Comput, vol. 56, pp. 491--504, doi:10.1007/s11517-017-1696-9
D. Hernando, N. Garatachea, R. Almeida, J. A. Casajús, R. Bailón (2017). Validation of heart rate monitor Polar RS800 for heart rate variability analysis during exercise. Journal of Strength and Conditioning Research, vol.32, n.3 pp. 716–725, doi: 10.1519/JSC.0000000000001662
L. Sörnmo, A. Petrenas, P. Laguna, V. Marozas] (2018). BookChapter: Extraction of f waves. in Atrial Fibrillation from an Engineering Perspective, Springer. pp. 137-220, DOI: 10.1007/978-3-319-68515-1_5
L. Sörnmo, R. Alcaraz, P. Laguna, J. Rieta] (2018). BookChapter: Characterization of f waves. in Atrial Fibrillation from an Engineering Perspective, Springer. pp. 221-280, DOI: 10.1007/978-3-319-68515-1_6
L. Sörnmo, Editor (2018) Atrial Fibrillation from an Engineering Perspective, Series in Bioengineering, Springer, doi: 10.1007/978-3-319-68515-1

Conference Proceedings

J. Garrido, I. López-Laval, D. Hernando, N. Garatachea, R. Bailón (2018). Relación entre la variabilidad del ritmo cardiaco y la fatiga en jugadores de baloncesto profesionales. XXXVI Congreso Anual de la Sociedad Española de Ingenieríıa Biomédica, Ciudad Real, pp. 97-100,
P. Armañac, S. Kontaxis, J. Lázaro, P. Laguna, R. Bailón, E. Gil2 (2018) Cambios en la Diferencia del Tiempo de Tránsito del Pulso Sanguíneo en Estados de Estrés Emocional Agudo XXXVI Congreso Anual de la Sociedad Española de Ingenieríıa Biomédica, Ciudad Real, pp. 125-128
V. Monasterio, E. Pueyo, J. F. Rodríguez-Matas, J. Carro (2018). Influencia de la corriente de estimulación en las diferencias entre simulaciones electrofisiológicas de célula y tejido. XXXVI Congreso Anual de la Sociedad Española de Ingenieríıa Biomédica, Ciudad Real, pp. 1,
N. Ortigosa, M. Rodriguez-Lopez, R. Bail´on, A. Sepulveda, F. Crispi, P. Laguna (2018). Diferencias morfológicas en ECG de adultos que tuvieron Crecimiento Intrauterino Retardado. XXXVI Congreso Anual de la Sociedad Española de Ingenieríıa Biomédica, Ciudad Real, pp. 111-114,
E. Ramos-Marqués, L. García-Mendívil, J. C. Oliveros, R. Torres-Pérez, A. Oliván, L. Ordovás, E. Pueyo (2018). Analysis of the role of microRNA in age-related heart electrophysiological remodeling. Aging and Metabolism, Cell Symposia, Sitges, Spain.
L. García-Mendívil, E. Ramos-Marqués, J. C. Oliveros, R. Torres-Pérez, J. Fernández-Bes, A. Oliván, E. Pueyo, L. Ordovás (2018) Transcriptional analysis of human cardiac aging by chronological and biological age. Aging and Metabolism, Cell Symposia, Sitges, Spain.
D. Hernando, R. McCallister, J. Lazaro, K.Hocking, E. Gil, P. Laguna, C. Brophy, R.
Bailón (2018). Validity of Venous Waveform Signal for Heart Rate Variability Monitoring. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.289
S. Kontaxis, M. Orini, E. Gil, M. Posadas-De Miguel, M. L. Bernal, J. Aguiló, C. de la Camara, P. Laguna, R. Bailón (2018) Heart Rate Variability Analysis Guided by Respiration in Major Depressive Disorder. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.319.
J. Lazaro, R. Bailón, E. Gil, Y. Noh, P. Laguna, K. Chon (2018) Pilot Study on Electrocardiogram Derived Respiratory Rate Using a Wearable Armband. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI: : 10.22489/CinC.2018.054
N. Ortigosa, M. Rodriguez-Lopez, R. Bailón, A. Sepulveda, F. Crispi, P. Laguna (2018) Intrauterine Growth Restriction Induced ECG Morphological Differences Measured in Adulthood. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:: 10.22489/CinC.2018.302
A. Rodrigues, A. Petrėnas, N. Kušleikaitė-Pere, P. Laguna, V. Marozas (2018). ECG-Based Monitoring of Electrolyte Fluctuations During the Long Interdialytic Interval. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.277
J. Ramírez, S. van Duijvenboden, P. Laguna, E. Pueyo, A. Tinker, P. Lambiase, P. Munroe, M. Orini (2018) Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.039
F. Palmieri, J. P. Martínez, L. Burattini, J. Ramírez (2018). T-Wave Morphology Restitution in Chronic Heart Failure Patients With Atrial Fibrillation. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.177
S. Palacios, E. Caiani, J. P. Martínez, E. Pueyo (2018) Microgravity Exposure Alters Sympathetic Modulation of Ventricular Repolarization Quantified from the ECG via Periodic Repolarization Dynamics. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.358
A. Martin, J. P. Martínez (2018) A Wavelet-Based Approach for Automatic Diagnosis of Strict Left Bundle Branch Block. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.154
J. Bolea, G. Valenza, R. Bailón, E. Pueyo, R. Barbieri (2018). Inhomogeneous Heart Rate Variability Spectral Complexity: A Preliminary Evaluation With Gravitational Stimuli Under Selective Autonomic Blockade. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.312
J. Morales, M. Deviaene, J. Milagro, D. Testelmans, B. Buyse, R. Bailón, R. Willems, S. Van Huffel, C. Varon (2018). Respiratory Sinus Arrhythmia in Apnea Patients With Apnea Associated Comorbidities. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.091
J. Milagro, D. Hernando, J. Lazaro, J. Antonio Casajús, N. Garatachea, E. Gil, R. Bailón (2018) On Deriving Tidal Volume From Electrocardiogram During Maximal Effort Test. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.288
G. R. Ríos-Muñoz, S. Rocher, A. Artés-Rodríguez, A. Arenal, J. Saiz, C. Sánchez (2018) Patient-Tailored In Silico 3D Simulations and Models From Electroanatomical Maps of the Left Atrium. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:: 10.22489/CinC.2018.183
M. Deviaene, J. Lázaro, D. Huysmans, D. Testelmans, B. Buyse, S. Van Huffel, C. Varon (2018). Sleep Apnea Detection Using Pulse Photoplethysmography. Proceedings of the XLV International Conference on Computing in Cardiology. Maastricht, Netherlands. pp. 1-4, DOI:10.22489/CinC.2018.134
M. Nardelli, A. Greco, G. Valenza, A. lanata, R. Bailón, E. Scilingo (2018) A Multiclass Arousal Recognition Using HRV Nonlinear Analysis and Affective Images. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). pp. 392-395
J. Lazaro, S. Kontaxis, R. Bailón, P. laguna, E. Gil (2018) Respiratory Rate Derived from Pulse Photoplethysmographic Signal by Pulse Decomposition Analysis. 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). pp. 5282-5285
A. Alcaine, D. Soto-Iglesias, J. Acosta, D. Penela, D. Andreu, J. Fernandez-Armenta, P. Laguna, O. Camara, J.P. Martinez, A. Berruezo. (2018) Slow conducting channel identification from electroanatomical maps using an automatic algorithm in patients with scar-related ventricular arrhythmias. EHRA Congress 2018, 18-20 Marzo (Barcelona, Spain). EP Europace, Volume 20, Issue suppl_1, 1 March 2018, Pages i136–i137
A. Alcaine, D. Soto-Iglesias, J. Acosta, V. Korshunov, D. Penela, D. Andreu, J. Fernandez- Armenta, P. Laguna, J. P. Martinez, O. Camara, A. Berruezo (2018) Clinical evaluation of an automatic activation mapping algorithm for identifying the site of origin of idiopathic ventricular arrhythmias. EHRA Congress 2018, 18-20 Marzo (Barcelona, Spain) EP Europace, Volume 20, Issue suppl_1, 1 March 2018, Pages i137
J.L Pérez-Lasierra, N.Garatachea, R. Bailón, D. Hernando, J.A. Casajús (2018) Heart rate variability, maximal oxigen uptake and anaerobic threshold. 23th Congress of the European college of sport science, Dublin
J. Fernández-Bes; D. A. Sampedro; P. Taggart; E. Pueyo (2018). Time Course of Cardiac Electrical Oscillatory Behavior in Response to Enhanced Sympathetic Activity and Relation to Arrhytmogenesis.. 10th European Study Group on Cardiovascular Oscillations. Viena, (Austria). Septiembre 2018
J. Fernández-Bes; D. A. Sampedro; E. Pueyo. (2018) A Bayesian Filtering methodology to identify key drivers of ventricular repolarization variability. V Conf. Virtual Physiological Human Conference VPH2018. Zaragoza, (España). Septiembre 2018.
D. A. Sampedro; L. García; E. Ramos; A. Olivan; J. Fernández-Bes; E. Pueyo (2018). Cardiac dynamics and arrhythmic risk in aged and failing hearts: insights from experimental and computational research. V Conf. Virtual Physiological Human Conference VPH2018. Zaragoza (España). Septiembre 2018.
D. A. Sampedro; J. Fernández-Bes; B. Porter; S. von Duijvenboden; P. Taggart; E. Pueyo (2018) . Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat repolarization variability under sympathetic provocation. V Conf. Virtual Physiological Human Conference. Zaragoza (España). Septiembre 2018.
D. A. Sampedro; J. Fernández-Bes; B. Porter; S. von Duijvenboden; P. Taggart; E. Pueyo (2018). Mechanisms underlying interactions between low-frequency oscillations and beat-to-beat repolarization variability in human ventricles under sympathetic provocation. European Working Group on Cardiac Cellular Electrophysiology (EWGCCE).Poster, Essen (Alemania). Junio 2018.
A. Hernández-Vicente; D. Hernando; D. Navarrete-Villanueva; I. López-Laval; G. Vicente-Rodríguez; E. Pueyo; R. Bailón; N. Garatachea (2019) La actividad del Sistema Nervioso Autónomo en reposo está relacionada con el nivel de condición física, IV Simposio EXERNET Investigación en Ejercicio, Salud y Bienestar "Exercise is Medicine", Pamplona, octubre de 2018 Entidad organizadora: EXERNET Red Española de Investigación en Ejercicio Físico y Salud

Ph.D. Thesis

J. Bolea (2018). Novel Framework for Nonlinear HRV Analysis and its Physiological Interpretation. Zaragoza University

Patents

J. Aguilo, J.M. Garzón, A. Arza, T. Tsapikouni, E. Garcia, K. Spyridon, P. Laguna, R. Bailon. J. Lazaro (2018) ref. P4175EP00. Methods and systems for measuring a stress indicator, and for determining a level of stress in an individual.
L. Iozzia, L. Mainardi, J. Bolea (2018) ref. P2957IT00 Cardiac activity measurement system and method thereof.

2017

Journals and Books

J. Fernandez-Bes; J. Arenas-García; M. T. M. Silva; L A. Azpicueta-Ruiz (2017). Adaptive Diffusion Schemes for Heterogeneous Network s. IEEE Transactions on Signal Processing, 65 (21), pp. 5661 - 5674, ISSN: 1941-0476. doi: 10.1109/TSP.2017.2740199
C. Sánchez, A. Bueno-Orovio, E. Pueyo, B. Rodríguez B. (2017) Atrial Fibrillation Dynamics and Ionic Block Effects in Six Heterogeneous Human 3D Virtual Atria with Distinct Repolarization Dynamics. Front Bioeng Biotechnol. 8;5:29. doi: 10.3389/fbioe.2017.00029.
W. Naujock, M. Fumagalli, L. Vandoorne, T. Baatsen, P. Boon, L. Ordovás, A. Patel, A. M. Welters, T. Vanwelden, et al. (2017). HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nat. Commun. 8, 861. DOI: 10.1038/s41467-017-00911-y
J. Ramírez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz, A. Bayés de Luna; J. P. Martínez, P. Laguna, E. Pueyo, (2017) Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model. PLOS ONE, 12 (10): e0186152 pp. 1-15 doi:10.1371/journal.pone.0186152
J. P. Martinez, P. Laguna (2017) Editorial: Measuring of ventricular repolarization dynamics from ambulatory ECG as non-invasive cardiac risk indices. Revista Clínica Española. 217(8): pp. 460--461, doi:10.1016/j.rce.2017.09.001
M. Turon, S. Fernandez-Gonzalo, M. Jodar, G. Goma, J. Montanya, D. Hernando, R. Bailon, C. de Haro, V. Gomez-Simon, J. Lopez-Aguilar, R. Magrans, M. Martinez-Perez, J. C. Oliva, L. Blanch, (2017). Feasibility and safety of virtual-reality-based early neurocognitive stimulation in critically ill patients. Annals of Intensive Care. vol.7, n.81 pp: 1-11, doi:10.1186/s13613-017-0303-4
J. Bolea, J. Lázaro, E. Gil, E. Rovira, J. M. Remartínez, P. Laguna, E. Pueyo, A. Navarro, R. Bailón, (2017) Pulse rate and transit time analysis to predict hypotension events after spinal anesthesia during programmed cesarean labor. Annals Biomedical Enginnering, vol. 45, n. 9, pp. 2253–2263 DOI: 10.1007/s10439-017-1864-y
A. Martín-Yebra, F. Landreani, C. Casellato, E. Pavan, P.-F. Migeotte, C. Frigo, J.P. Martínez, E.G. Caiani (2017) Evaluation of respiratory- and postural-induced changes on the ballistocardiogram signal by time warping averaging. Physiological Measurements vol 38, pp: 1426–1440 doi.org/10.1088/1361-6579/aa72b0.
J. Ramirez, M. Orini, A. Mincholé, V. Monasterio, I. Cygankiewicz; A. Bayés de Luna, J. P. Martínez, E. Pueyo, P. Laguna, (2017) T-wave Morphology Restitution Predicts Sudden Cardiac Death in Patients with Chronic Heart Failure. Journal of the American Heart Association. 6:e005310; doi: 10.1161/JAHA.116.005310. p:1-12.
D.G. Strauss, J. Vicente, L. Johannesen, K. Blinova, J. W. Mason, P. Weeke, E.R. Behr, D. Roden, R. Woosley, G. Kosova, M.A. Rosenberg, C. Newton-Cheh, (2017). A Common Genetic Variant Risk Score is Associated with Drug-Induced QT Prolongation and Torsade de Pointes Risk: A Pilot Study. Circulation AHA; 135:1300–1310. DOI: 10.1161/CIRCULATIONAHA.116.023980
J. Carro, J. F. Rodríguez-Matas, V. Monasterio, E. Pueyo (2017) Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols. Progress in Biophysics and Molecular Biology. vol. 129, pp. 53-64, doi: 10.1016/j.pbiomolbio.2016.11.006
M. Orini, P. Laguna , L.T. Mainardi, and R. Bailón (2017). BookChapter: Time-frequency analysis
of cardiovascular signals and their dynamic interactions. in Complexity in Cardiovascular Signals. Springer. doi: 10.1007/978-3-319-58709-7_9
J. Ramírez, M. Orini, J. D. Tucker, E. Pueyo and P. Laguna (2017). Variability of ventricular repolarization dispersion quantified by time-warping the morphology of the T-waves. IEEE Transactions Biomedical Engineering. Vol. 64, n. 7, pp. 1619--1630: doi: 10.1109/TBME.2016.2614899
A. Alcaine, M. Masè, A. Cristoforetti, F. Ravelli, G. Nollo, P. Laguna, J. P. Martínez, L. Faes (2017) , A Multi-Variate Predictability Framework to Assess Invasive Cardiac Activity and Interactions during Atrial Fibrillation. IEEE Transactions Biomedical Engineering. vol. 64, n. 5, pp. 1157-1168. doi:10.1109/TBME.2016.2592953.
K. Blinova, J. Stohlman, J. Vicente, D. Chan, L. Johannesen, M. P. Hortigon-Vinagre, V. Zamora, G. Smith, W. J. Crumb, L. Pang, B. Lyn-Cook, J. Ross, M. Brock, S. Chvatal, D. Millard, L. Galeotti, N. Stockbridge, D. G. Strauss (2017) Comprehensive Translational Assessment of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced ArrhythmiasToxicol. Toxicological Sciences, vol. 155 , n. 1, pp. 234-247. doi:10.1093/toxsci/kfw200
A. Garde, L. Sörnmo, P. Laguna, R. Jané, S. Benito, A. Bayes-Genis, B. Giraldo (2017) Assessment of Respiratory Flow Cycle Morphology in Patients with Chronic Heart Failure, Medical & Biological Enginering & Computing, Med Biol Eng Comput vol. 55: pp. 245–255. DOI 10.1007/s11517-016-1498-5
O. Barquero-Pérez, C. Figuera, R. Goya-Esteban, I. Mora-Jiménez, F. J. Gimeno-Blanes, P. Laguna, J. P. Martínez, E. Gil, L. Sörnmo, A. García-Alberola, J. L. Rojo-Álvarez, (20017). On the Influence of Heart Rate and Coupling Interval Prematurity on Heart Rate Turbulence.IEEE Transactions Biomedical Engineering. vol. 64, n.. 2, pp. 302-309. doi: 10.1109/TBME.2016.2554614
E. Grigonyte, E. Gil, P. Laguna, L. Sornmo (2017) Relative Peripheral Blood Volume Changes Induced by Premature Ectopic Beats and Their Role in Hemodialysis (Technical Note). Biomedical Signal Processing and Control. vol. 31 pp. 524–528, doi.org/10.1016/j.bspc.2016.09.020
G. Lenis, M. Kircher, J. Lázaro, R. Bailón, E. Gil,O Doessel (2017) Separating the effect of respiration on the heart rate variability using Granger’s causality and linear filtering. Biomedical Signal Processing and Control. vol. 31 pp. 272–287, doi.org/10.1016/j.bspc.2016.07.014

Conference Proceedings

D. Hernando, M. Kähönen, J. Lázaro, R. Lehtinen, T. Nieminen, K. Nikus, T. Lehtimäki, R. Bailón and J. Viik (2017) Coronary artery disease diagnosis by means of heart rate variability analysis using respiratory information, Proceedings of the EMBEC 2017, NBC 2017, pp. 270-273. DOI: 10.1007/978-981-10-5122-7_68
J. Milagro, E. Gil1, J. Bolea, V-P. Seppä, L.P. Malmberg, A.S. Pelkonen, A. Kotaniemi-Syrjänen, M.J. Mäkelä, J. Viik and R. Bailón (2017) Nonlinear Dynamics of Heart Rate Variability in Children with Asthmatic Symptoms. Proceedings of the EMBEC 2017, NBC 2017, pp. 815-818 DOI: 10.1007/978-981-10-5122-7_204
J. Ramírez, M. Orini, E. Pueyo and P. Laguna (2017), Quantification of T-wave Morphological Variability Using Time-warping Methods, Proceedings of the EMBEC 2017, NBC 2017, pp. 478-481 DOI: 10.1007/978-981-10-5122-7_120
J. Carro, J.F. Rodríguez Matas E. Pueyo (2017), Multiscale Methods for Definition of Ionic Variables in Electrophysiological Models, Proceedings of the EMBEC 2017, NBC 2017, pp. 115
A.Lyon, R.Ariga, A.Mincholé, E.Zacur, P.Laguna, V.Grau, S.Neubauer, H.Watkins and B.Rodriguez (2017)
Risk stratification in hypertrophic cardiomyopathy using ECG-based clustering and personalized computer simulations, Proceedings of the EMBEC 2017, NBC 2017, pp. 104.
A. Alcaine, D. Soto-Iglesias, J. Acosta, D. Penela, P. Laguna, J. P. Martínez, O. Camara, A. Berruezo (2017) Identificación del lugar de origen de arritmias ventriculares idiopáticas relacionadas con el tracto de salida usando un algoritmo de mapeo automático de activación, Revista Española de Cardiología, Vol. 70 (Suppl. 1), SEC 2017 - El Congreso de las Enfermedades Cardiovasculares, pp. 294, 2017.
A. Alcaine, D. Soto-Iglesias, J. Acosta, D. Penela, P. Laguna, O. Camara, J. P. Martínez, A. Berruezo (2017). Delineación automática de canales de conducción lenta en mapas electroanatómicos de pacientes con arritmias ventriculares debidas a cicatriz posinfarto, Revista Española de Cardiología, Vol. 70 (Suppl. 1), SEC 2017 - El Congreso de las Enfermedades Cardiovasculares, pp. 573, 2017.
A. Alcaine, D. Soto-Iglesias, J. Acosta, D. Penela, D. Andreu, J. Fernandez-Armenta, P. Laguna, O. Camara, J.P. Martinez, A. Berruezo (2017). Automatic delineation of slow conducting channels from electroanatomical maps in patients with scar-related ventricular arrhythmias. ESC conference published at European Heart Journal, Volume 38, Issue suppl_1, 1 ehx501.P795
F. Landreani, A. Martin-Yebra, C. Casellato, E. Pavan, C. Frigo, P-F. Migeotte, A. Faini, G. Parati, E.G. Caiani (2017). Respiratory Frequency Estimation from Accelerometric Signals Acquired by Mobile Phone in a Controlled Breathing Protocol . Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4, DOI:10.22489/CinC.2017.137-402.
D. A. Sampedro-Puente, J. Fernandez-Bes, E. Pueyo (2017). Differential Responses to Beta-Adrenergic Stimulation in the Long-QT Syndrome Type 1: Characterization and Mechanisms. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4, DOI:10.22489/CinC.2017.250-453.
J. Fernandez-Bes, D. A. Sampedro-Puente, E.Pueyo (2017). Identification of Parameters describing Phenomenological Cardiac Action Potential Models using Sigma-Point Methods. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.060-109.
C. Sánchez, M. Peláez-Coca, M. T. Lozano, M. Aiger, A. Hernando, E. Gil (2017). Autonomic Nervous System Non-stationary Response to Controlled Changes in Barometric Pressure. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.281-333.
M. Peláez, M. T. Lozano, M. Aiger, A. Hernando, E. Gil (2017). Significant Physiological Features to Identify High Performance States. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.280-141.
C. Varon, Jesús Lázaro, A. Hernando, A. Caicedo, S. Van Huffel, R. Bailón4 (2017). Removal of Respiratory Influences from Heart Rate During Emotional Stress. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.264-160.
J. Milagro, E. Gil, J. M. Garzón-Rey, J. Aguiló, R. Bailón (2017). Inspiration and Expiration Dynamics in Acute Emotional Stress Assessment. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.261-411.
D. Hernando, N. Garatachea, J. A. Casajús, R. Bailón (2017). Comparison of Heart Rate Variability Assessment During Exercise from Polar RS800 and ECG. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.206-225.
E. Peralta, J. Lázaro, E. Gil1, R. Bailón1, V. Marozas (2017). Robust Pulse Rate Variability Analysis from Reflection and Transmission Photoplethysmographic Signals. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.205-286.
J. M. Garzón-Rey, J. Lázaro, J. Milagro, E. Gil, J. Aguiló, R. Bailón (2017). Respiration-Guided Analysis of Pulse and Heart Rate Variabilities for Acute Emotional Stress Assessment. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.318-093.
J. Lázaro, E. Gil, M. Deviaene, R. Bailón, D. Testelmans, B. Buyse, C. Varón1, S. Van Huffel (2017). Pulse Photoplethysmography Derived Respiration for Obstructive Sleep Apnea Detection. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.273-229.
S. Banerjee, R. Bailón, J. Lazáro, V. Marozas, P. Laguna, E. Gil (2017). A Two Step Gaussian Modelling to Assess PPG Morphological Variability Induced by Psychological Stress. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.270-035.
J. P. Martínez, O. Pahlm, M. Ringborn, S. Warren, P. Laguna, L. Sörnmo (2017). The STAFF III Database: ECGs Recorded During Acutely Induced Myocardial Ischemia. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.266-133.
J. Ramírez, M. Orini, E. Pueyo, P. Laguna (2017). Comparison of ECG T-wave Duration and Morphology Restitution Markers for Sudden Cardiac Death Prediction in Chronic Heart Failure. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.224-267.
J. Ramírez, M. Orini, E. Pueyo, P. Laguna (2017). T-wave Morphology Restitution Dependency with Heart Rate Range and Its Association with Sudden Cardiac Death in Chronic Heart Failure. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.221-009.
A. Martín-Yebra, V. Monasterio, P. Laguna, J. P. Martínez, E. G. Caiani (2017). Evaluation of Changes in T-wave Alternans Induced by 60-days of Immobilization by Head-Down Bed-Rest. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.038-430.
L. Iozzia, J. Lázaro, E. Gil, L. Cerina, L. Mainardi, P. Laguna (2017). Respiratory Rate Detection Using a Camera as Contactless Sensor. Proceedings of the XLIV International Conference on Computing in Cardiology. Rennes, France. pp. 1-4. DOI:10.22489/CinC.2017.028-317.
D. A. Sampedro; J. Fernández-Bes; E. Pueyo (2017) Caracterización de las respuestas a la estimulación beta-adrenérgica en escenarios de síndrome LQT1. Congreso: XXXV Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Bilbao (España).
J. Fernández-Bes; D. A. Sampedro; E. Pueyo (2017). Unscented Kalman Filter para el ajuste de parámetros de modelos fenomenológicos de potencial de acción. Congreso: XXXV Congreso de la Sociedad Española de Ingeniería Biomédica CASEIB. Bilbao (España).
A. Hernando, M. Peláez, M.T. Lozano, M. Aiger, E. Gil, J. Lázaro (2017) Finger and Forehead PPG Signal Comparison for Respiratory Rate Estimation Based on Pulse Amplitude Variability. 25th European Signal Processing Conference (EUSIPCO), Kos, Grecia. pp. 2130-2134 DOI:10.23919/EUSIPCO.2017.8081575

Ph.D. Thesis

J. Ramirez (2017). Prediction of Cardiac Death Risk by Analysis of Ventricular Repolarization Restitution from the Electrocardiogram Signal. Zaragoza University
D. Hernando (2017) Non-Invasive Assessment of Autonomic Nervous System through Cardiovascular Signals Variability Analysis in Non-Stationary Environments. Zaragoza University
A. Martin (2017) Assessment of ventricular repolarization instability and cardiac risk stratification in different pathological and abnormal conditions, Politecnico Milano / Zaragoza University

2016

Journals and Books

J. Bolea, E.Pueyo, M. Orini and R. Bailón R (2016) Influence of heart rate in nonlinear HRV indices as a
sampling rate effect evaluated on supine and standing. Front. Physiol. 7:501. p.1-12; doi:10.3389/fphys.2016.00501
J. Vicente, L. Johannesen, M. Hosseini, J. W. Mason, ,P. T. Sager, E. Pueyo, D. G. Strauss (2016) Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block. Detection of Late Sodium Current Block on the ECG. PLOSONE. pp. 1-16, DOI:10.1371/journal.pone.0163619
L. Johannesen1, J. Vicente, M. Hosseini, D. G. Strauss (2016) Automated Algorithm for J-Tpeak and Tpeak-Tend Assessment of Drug-Induced Proarrhythmia Risk PLOSONE. pp. 1-18, DOI:10.1371/journal.pone.0166925
E. G. Caiani, A. Martin-Yebra, F. Landreani, J. Bolea, P. Laguna, P. Vaïda (2016) . Weightlessness and cardiac rhythm disorders: current knowledge from space flight and bed-rest studies. Frontiers in Astronomy and Space Sciences, vol. 3. Arcicle 27, pp.1-6. doi: 10.3389/fspas.2016.00027
Daluwatte, L. Johannesen, L Galeotti, J Vicente, D G Strauss and C G Scully (2016), Assessing ECG signal quality indices to discriminate ECGs with artefacts from pathologically different arrhythmic ECGs. Physiolocal Measurements. vol. 37, pp.1370–1382.
E. Pueyo, C. E. Dangerfield. J. Britton. Virág, K. Kistamás, N. Szentandrássy6, N. Jost, A. Varró, P. P. Nánási, K. Burrage, B. Rodríguez (2016). Experimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibition PLOSONE pp. 1-20 doi: 10.1371/journal.pone.0151461
E. Pueyo M. Orini, J. F. Rodríguez, P. Taggart. (2016) Interactive effect of beta-adrenergic stimulation and mechanical stretch on low-frequency oscillations of ventricular action potential duration in humans Journal of Molecular and Cellular Cardiology vol. 97, pp. 93–105. doi: 10.1016/j.yjmcc.2016.05.003
A. Hernando, J. Lázaro, E. Gil, A. Arza, J. M. Garzón, R. López-Antón, C. de la Cámara, P. Laguna, J. Aguiló, R. Bailón (2016). Inclusion of respiratory frequency information in heart rate variability analysis for stress assessment. IEEE Journal of Biomedical and Health Informatics. Vol. 20, n. 4, pp. 1016-1025 doi: 10.1109/JBHI.2016.2553578.
A. Alcaine, N. M. de Groot, P. Laguna, J. P. Martínez, R. P. Houben (2016) Spatiotemporal Model-Based Estimation of High-Density Atrial Fibrillation Activation Map. Digital Signal Proceesing, vol. 54, pp. 64--74, doi: 10.1016/j.dsp.2016.04.002
D.Romero; J. P. Martinez, P.Laguna, E. Pueyo (2016). Ischemia detection from morphological QRS angles changes. Physiological Measurement. Vol. 37, pp. 1004--1023 doi: 10.1088/0967-3334/37/7/1004
M. M. Demidova, A. Martín-Yebra, S. Koul, E. H, J. P. Martínez, D. Erlinge, P. G. Platonov, (2016) QRS broadening due to terminal distortion is associated with the size of myocardial injury in experimental myocardial infarction. J Electrocardiol, DOI: 10.1016/j.jelectrocard.2016.03.014 vol. 49, n. 3. pp: 300-306
N. Ortigosa, M. Rodriguez-Lopez, R. Bailón , S. I. Sarvarie, M. Sitges, E. Gratacos, B. Bijnens, F. Crispi, P. Laguna, (2016) Heart morphology differences induced by intrauterine growth restriction and preterm birth measured on the ECG at preadolescent age. J Electrocardiol, DOI: 10.1016/j.jelectrocard.2016.03.011. Vol. 49, n. 3, pp. 401–409
J. Vicente P. Laguna, A. Bartra R. Bailon (2016). Drowsiness Detection using Heart Rate Variability, Medical & Biological Enginering & Computing, vol. 54, pp.927-937. DOI 10.1007/s11517-015-1448-7
P. Laguna, J.P. Martinez, E. Pueyo (2016). Techniques for ventricular repolarization instability assessment from the ECG. Proceedings of the IEEE. Vol. 104, n. 2; pp. 392-415. doi: 10.1109/JPROC.2015.2500501
M. Baumert, A. Porta, M. A. Vos, M. Malik, J.P. Couderc, P. Laguna, G. Piccirillo, G. L. Smith, L. G. Tereshchenko, P.G.A. Volders (2016). QT interval variability in body surface ECG: Measurement, physiological basis, and clinical value Position statement and consensus guidance. endorsed by the European Heart Rhythm Association jointly with the ESCWorking Group on Cardiac Cellular Electrophysiology, EP-Europace, doi:10.1093/europace/euv405

Conference Proceedings

F. Landreani, A. Martin-Yebra, C. Casellato, C. Frigo, E. Pavan, P-F Migeotte, E. G. Caiani. (2016) Beat-to-beat heart rate detection by smartphone's accelerometers: Validation with ECG. 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). pp. 525-528
Turon, M., Hernando, D., Fernandez-Gonzalo, S., Bailón, R., Gomà, G., Lázaro, J., Montanyà, J., Gil, E., de Haro, C., Martinez-Perez, M., López-Aguilar, J., Martinez-Rubio, A., Jodar, M., Laguna, P., Blanch, L. Differential effect of early neurocognitive rehabilitation on autonomic nervous system in critically ill patients with and without delirium. Am J Respir Crit Care Med 193;2016:A5272. American Thoracic Society (ATS) International Conference. San Francisco, 2016.
M. Turon, D. Hernando S. Fernandez-Gonzalo, G. Gomà, J. Montanyà, C. de Haro, M. Martinez-Perez, J. López-Aguilar, M. Jodar, L. Blanch. (2016) Reactividad del Sistema Nervioso Autónomo a la estimulación neurocognitive en el paciente crítico. Congreso Nacional de la Sociedad Española de Medicina Intensiva Crítica y Unidades Coronarias (SEMICYUC), Valencia, 2016.
M. Turon, S. Fernandez-Gonzalo, G. Gomà, J. Montanyà, R. Bailón, C. de Haro, M. Martinez-Perez, J. López-Aguilar, M. Jodar, L. Blanch. (2016) La presencia de delirium induce una respuesta diferencial del SNA a una estimulación neurocognitiva. Congreso Nacional de la Sociedad Española de Medicina Intensiva Crítica y Unidades Coronarias (SEMICYUC), Valencia, 2016.
A. Martín, I. Cygankiewicz, A. Bayés-de-Luna, P. Laguna, E.G. Caiani and J.P. Martínez (2016). Index of T-wave Variation as a Predictor of Sudden Cardiac Death in Chronic Heart Failure Patients with Atrial Fibrillation. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.002-366.
G. Lenis, R. Menges, J. Ramírez, I. Cygankiewicz, A. Bayés-de-Luna, J.P. Martínez, P. Laguna and Olaf Dössel (2016). Postextraystolic T Wave Change to Stratify Risk of Pump Failure Death in Patients with Chronic Heart Failure. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.011-402.
J. Ramírez, M. Orini, J.D. Tucker, E. Pueyo and P. Laguna (2016). An Index for T-wave Pointwise Amplitude Variability Quantification. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.016-137.
J. Lázaro, R. Bailón, P. Laguna, V. Mazoras, A. Rapalis and E. Gil (2016). Difference in Pulse Arrival Time at Forehead and at Finger as a Surrogate of Pulse Transit Time. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.079-432.
S. Kontaxis, J. Lázaro, A. Hernando, A. Arza, J.M. Garzón, E. Gil, P. Laguna, J. Aguiló y R. Bailón (2016). Mental Stress Detection Using Cardiorespiratory Wavelet Cross-Bispectrum. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.211-454.
M. Noriega, E. Carcases, E. Marañón, J.P. Martínez and R. Almeida (2016). Respiration Rate Estimation from Multilead ECG Delineation using VCG Directions on Fiducial Points. Proceedings of the XLIII International Conference on Computing in Cardiology. Vancouver, BC, Canada. DOI:10.22489/CinC.2016.115-151.
J. Castro, V. Monasterio, and J. Carro, (2016) Volunteer Computing Approach for the Collaborative Simulation of Electrophysiological Models,” in 2016 IEEE 25th International Conference on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE), 2016, pp. 118-123.
A. C. Marcén, J. Carro, and V. Monasterio, (2016) Wearable Monitoring for the Detection of Nocturnal Agitation in Dementia,” in Proceedings of the 6th International Joint Conference on Pervasive and Embedded Computing and Communication Systems, 2016, pp. 63-69.
S. Kontaxis, J. Lázaro, A. Hernando, A. Arza, J. M. Garzón, E. Gil2, P. Laguna, J. Aguiló, R. Bailón (2016) Detección de Estrés Mental mediante el Wavelet Cross-Bispectrum Cardiorrespiratorio pp. 22-25 Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-9048-531-6
J. Ramírez, M. Orini, J. D. Tucker, E. Pueyo, P. Laguna (2016) Cuantificación de la Variabilidad de la Amplitud de la Onda T Mediante Técnicas de Re-parametrización Temporal. pp. 392-395 Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-9048-531-6
A. Martín-Yebra, I. Cygankiewicz, A. Bayés-de-Luna, P. Laguna, E. Caiani1, J.P. Martínez (2016) Índice de variación de la onda T como predictor de muerte súbita cardíaca en pacientes con insuficiencia cardiaca en fibrilación auricular, pp. 194-197 Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-9048-531-6
A García-Escolano, M.T. Mora, V. Monasterio, J.F. Rodríguez, J.M. Ferrero (2016). Estudio mediante modelado y simulación del efecto de la isquemia miocárdica aguda en las fibras de Purkinje de corazón humano. pp 471-474 Proceedings XXXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-9048-531-6

Ph.D. Thesis

J. Vicente (2016). Novel Electrocardiographic Biomarkers for Proarrhythmic Assessment of Drugs. Zaragoza University
A. Alcaine (2016). Intracardiac Signal Processing for Mapping and Characterising Cardiac Arrhythmias. Zaragoza University

Patents

A. Alcaine, A. Berruezo, O. Camara, P. Laguna, J. P. Martínez y D. Soto-Iglesias (2016) : ref: 160022224. A computer implemented method to identify the ventricular arrhythmogenic substrate in myocardial
scar or fi brotic tissue and computer programs thereof

2015

Journals and Books

M. Lorenzo-Tejedor, C. De la Cámara, R. Lopez-Anton, R. Bailón, J. Aguiló, ML. Bernal Ruiz (2015). Direct Infussion Electrospray Mass Spectrometry as a new non-invasive tool for Serum Metabolomics in Induced-Stress Subject. European Journal of Psychiatry. Vol. 29, N.° 4, pp. 259-275.
D. Hernando, L. Sörnmo, F. Sandberg, P. Laguna, M. Llamedo, R. Bailón (2015). Identification of Hypotension Prone Patients During Hemodialysis based on the Analysis of Heart Rate Variability, Medical & Enginering & Physics, Vol. 37, n.12 , pp. 1156-1161 doi:10.1016/j.medengphy.2015.10.003
J. Aguiló, P. Ferrer-Salvans, A. García-Rozo, A.Armario, A. Corbí, F.J. Cambra, R. Bailón, A. González-Marcos, G. Caja, S. Aguiló, R. López-Antón, A. Arza-Valdés, J. M. Garzón-Rey (2015) . Project ES3: attempting to quantify and measure the level of stress. Rev Neurol; 61: 405-15.
J. Lazaro, Y. Nam, E. Gil, P. Laguna, K. Chon (2015) Respiratory rate derived from smartphone-cameraacquired pulse photoplethysmographic signals, Physiological Measurement, vol. 36, pp. 2317-2333 doi:10.1088/0967-3334/36/11/2317
J. Vicente, L. Johannesen, J. W. Mason, E. Pueyo, N. Stockbridge, D. G. Strauss (2015) Sex Differences in Drug-Induced Changes in Ventricular Repolarization. J Electrocardiol, 48 (2015) 1081 – 1087 doi: 10.1016/j.jelectrocard.2015.08.004
A. Martin-Yebra, E. Caiani, V. Monasterio, A. Pellegrini, P. Laguna, J.P. Martinez (2015). Evaluation of T-wave alternans activity under stress conditions after 5 days and 21 days of sedentary head-down bed-rest., Physiological measurement, vol 36, pp. 2041– 2055, doi:10.1088/0967-3334/36/10/2041.
A. Mincholé, A. Bueno-Orovio, P. Laguna , E. Pueyo, and B. Rodriguez (2015). ECG-based estimation of dispersion of APD restitution as a tool to stratify sotalol-induced arrhythmic risk, Journal of Electrocardiology, vol. 48 pp. 867-873. doi: 10.1016/j.jelectrocard.2015.06.006
J. Vicente, L. Johannesen, J. W. Mason, W.J. Crumb, E. Pueyo, N. Stockbridge, D. G. Strauss (2015) Comprehensive T wave Morphology Assessment in a Randomized Clinical Study of Dofetilide, Quinidine, Ranolazine, and Verapamil. J Am Heart Assoc. 4: e001615 p:1-13, doi: 10.1161/JAHA.114.001615
J. Ramírez, V. Monasterio, A. Mincholé, M. Llamedo, G. Lenis, I. Cygankiewicz, A. Bayés de Luna, M. Malik, J. P. Martínez, P. Laguna, E. Pueyo, (2015) Automatic SVM classification of Sudden Cardiac Death and Pump Failure Death from Autonomic and Repolarization ECG Markers. Journal of Electrocardiology, vol. 48, pp. 551-557, doi:10.1016/j.jelectrocard.2015.04.002
P. MacFarlane, P. Laguna , G. Krastacic (2015) Computing in Cardiology (CinC) A report from the
41st Annual CinC meeting in Cambridge, MA, USA, head on 7-10 September 2014, Cardiopulse,
doi:10.1093/eurheartj/ehu483, pp. 331.
L. Galeotti, P. M. van Dam, L. Johannesen, J. Vicente, D. G. Strauss (2015), Computer simulations to investigate the causes of T-wave notching. Journal of Electrocardiology vol. 48, pp. 927 – 932.

Conference Proceedings

M. Turon, D. Hernando, S. Fernandez-Gonzalo, R. Bailón, G. Gomà, J. Lázaro, J. Montanyà, E. Gil,
M. Martinez-Perez, C. de Haro, J. López-Aguilar, A. Martinez-Rubio, M. Jodar, P. Laguna, L. Blanch. (2015) Effect of an early neurocognitive rehabilitation on autonomic nervous system in critically ill patients. Intensive Care Medicine Experimental 2015, 3(Suppl 1):A989. doi:10.1186/2197-425X-3-S1-A989.
V. Monasterio, J. Carro, E. Pueyo, J. F. Rodríguez (2015). The Role of Purkinje Automaticity as an Arrhythmia Mechanism in Hyperkalaemia. XLII International Conference on Computing in Cardiology. Nice, France, pp. 873-876. DOI: 10.1109/CIC.2015.7411050
A. Lyon, A. Mincholé, R. Ariga, P. Laguna, S. Neubauer, H. Watkins, N. de Freitas, B. Rodríguez (2015). Extraction of Morphological QRS-based Biomarkers in Hypertrophic Cardiomyopathy for Risk Stratification using L1 Regularized Logistic Regression. XLII International Conference on Computing in Cardiology. Nice, France, pp. 9-12. DOI: 10.1109/CIC.2015.7408573
D. Hernando, M. Turon, R. Bailón, S. Fernandez-Gonzalo, J. Lázaro, G. Gomá, E. Gil, J. Montanyà, J. López-Aguilar, C. de Haro, P. Laguna, L. Blanch (2015). Autonomic Nervous System Assessment in Critically Ill Patients Undergoing a Cognitive Rehabilitation Therapy. XLII International Conference on Computing in Cardiology. Nice, France, pp. 785-788. DOI: 10.1109/CIC.2015.7411028
N. Ortigosa, F. Crispi, R. Bailón, M. Rodriguez-Lopez, E. Gratacós, S. Savari, M. Sitges, B. Bijnens, P. Laguna (2015). Heart Morphology Differences Induced by Intrauterine Growth Restriction and Premature Birth Measured on the ECG in Pre-adolescents. XLII International Conference on Computing in Cardiology. Nice, France, pp. 797-800. DOI: 10.1109/CIC.2015.7411031
A. Alcaine, N. M. S. de Groot, P. Laguna, J. P. Martínez, R. P. M. Houben (2015).Estimation of High-Density Activation Maps During Atrial Fibrillation. XLII International Conference on Computing in Cardiology. Nice, France, pp. 825-828. DOI: 10.1109/CIC.2015.7411038
A. Martín-Yebra, E. G. Caiani, P. Laguna, V. Monasterio, J. P. Martínez (2015). Circadian Modulation on T-wave Alternans Activity in Chronic Heart Failure Patients. XLII International Conference on Computing in Cardiology. Nice, France, pp. 845-848. DOI: 10.1109/CIC.2015.7411043
A. Hernando, J. Lázaro, A. Arza, J. M. Garzón, E. Gil, P. Laguna, J. Aguiló, R. Bailón (2015). Changes in respiration during emotional stress. XLII International Conference on Computing in Cardiology. Nice, France, pp. 1005-1008. DOI: 10.1109/CIC.2015.7411083
C. Daluwatte, L. Johannesen, J. Vicente, C.G. Scully, L. Galeotti, D.G. Strauss (2015). Heart Beat Fusion Algorithm to Reduce False Alarms for Arrhythmias. XLII International Conference on Computing in Cardiology. Nice, France, pp.745-748. DOI: 10.1109/CIC.2015.7411018
P. Sousa, R. Almeida, M.J. Silva, A.P. Rocha (2015). Reliability Loss with Sampling Rate Reduction. XLII International Conference on Computing in Cardiology. Nice, France, pp. 689-692. DOI: 10.1109/CIC.2015.7411004
A. Martín-Yebra, F. Landreani, C. Casellato, E. Pavan, C. Frigo, P.F. Migeotte, E. G. Caiani (2015). Studying Heart Rate Variability from Ballistocardiography Acquired by Force Platform: Comparison with Conventional ECG. XLII International Conference on Computing in Cardiology. Nice, France, pp: 929-932. DOI: 10.1109/CIC.2015.7411064
A. Luís, A.S. Santos, C. Dias, R. Almeida, A.P. Rocha (2015) . Heart Rate Variability during Plateau Waves of Intracranial Pressure: A Pilot Descriptive Study. 37nd Annual International Conference of the IEEE EMBS. Milan, Italy, pp. 6142 - 6145. DOI: 10.1109/EMBC.2015.7319794
M. T. Valderas, J. Bolea, P. Laguna, M. Vallverdú, R. Bailón (2015). Human Emotion Recognition Using Heart Rate Variability Analysis with Spectral Bands Based on Respiration. 37nd Annual International Conference of the IEEE EMBS. Milan, Italy, 2015 pp. 6134-6137. DOI: 10.1109/EMBC.2015.7319792
V.D.A. Corino, S. Monacizzo, R. Sassi, L. T. Mainardi, J. P. Martínez (2015).Analysis of T-Wave Alternans in ambulatory recordings using the ADTWA index. 37nd Annual International Conference of the IEEE EMBS. Milan, Italy, 2015 pp. 402-405. DOI: 10.1109/EMBC.2015.7318384
A. Arza, J.M. Garzón, A. Hemando, J. Aguiló, R. Bailon (2015).Towards an objective measurement of emotional stress: Preliminary analysis based on heart rate variability. 37nd Annual International Conference of the IEEE EMBS. Milan, Italy, 2015 pp. 3331-3334. DOI: 10.1109/EMBC.2015.7319105
A. Hernando, D. Hernando, N. Garatachea, J.A. Casajús, R. Bailón (2015).Attenuation of the Influence of Cardiolocomotor Coupling in Heart Rate Variability Interpretation During Exercise Test. 37nd Annual International Conference of the IEEE EMBS. Milan, Italy, 2015 pp. 1508-1511. DOI: 10.1109/EMBC.2015.7318657
J. Vicente, L. Johannesen, J.W. Mason, W.J. Crumb, E. Pueyo, N. Stockbridge, D.G. Strauss. “Comprehensive Analysis of Novel Electrocardiographic Device Algorithms for Differentiating Arrhythmic Risk”. FDA Science Forum 2015. Silver Spring, MD. May 28, 2015.
J. Vicente, L. Johannesen, J.W. Mason, E. Pueyo, N. Stockbridge, D.G. Strauss. “Sex Differences in Drug-Induced Changes in Ventricular Repolarization”. International Society of Computerized Electrocardiology, San Jose, California, US. April 2015.
L. Galeotti, P. Van Dam, L. Johannesen, J. Vicente, D.G. Strauss (2015) . Computer Simulations to Investigate Causes of T-wave Notching. International Society of Computerized Electrocardiology San Jose, California, US.
A. Martin-Yebra, J. P. Martínez, V. Monasterio, P. Laguna, E. G. Caiani (2015). Evaluation of changes in T-wave alternans induced by 21-days of bedridden immobilization by head-down bed-rest. ESC; European Heart Journal
E.G. Caiani, A. Martin-Yebra, A. Pellegrini, J. Bolea, A.Auricchio, E. Pueyo, P. Vaida (2015). High protein intake supplementation to compensate changes in ventricular repolarization due to 21-days of bedridden immobilization. ESC; European Heart Journal

Ph.D. Thesis

J. lazaro (2015) Non-invasive techniques for respiratory information extraction based on pulse photoplethysmogram and electrocardiogram. Zaragoza University

2014

Journals and Books

J.M. Gorriz, J Ramirez, A. Olivares, P. Padilla, C.G. Puntoner, M. Cantón and P. Laguna (2014). Real Time QRS Detection based on M-ary Likelihood Ratio Test on the DFT coefficients. PLOS ONE, Vol. 9, n. 10, e110629, doi:10.1371/journal.pone.0110629
J. Ramírez, P. Laguna, A. Bayés de Luna, M. Malik, E. Pueyo (2014). QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death, Journal of Electrocardiology, vol. 47 pp. 842– 848 doi: 10.1016/j.jelectrocard.2014.08.013
O. Sayadi, D. Puppala, N. Ishaque, R. Doddamani, F. M Merchant, C. Barrett, J. P Singh, E. K. Heist, T. Mela, J. P. Martínez, P. Laguna, A. A Armoundas, (2014) A Novel Method to Capture the Onset of Dynamic Electrocardiographic Ischemic Changes and its Implications to Arrhythmia Susceptibility. Journal of the American Heart Association (JAHA). e001055; pp. 1-13 doi: 10.1161/JAHA.114.001055 3:
J. Lazaro, A. Alcaine, D. Romero, E. Gil, P. Laguna, E. Pueyo, and R. Bailón, (2014). Electrocardiogram Derived Respiratory Rate from QRS Slopes and R-wave Angle. Annals Biomedical Enginnering, Vol. 40, No. 10, October 2014, pp. 2072–2083 DOI: 10.1007/s10439-014-1073-x
A. Mincholé, L. Sörnmo, and P. Laguna (2014). Detection of Body Position Changes from the ECG using a Laplacian Noise Model , Biomedical Signal Processing and Control, vol. 14 pp. 189--196 doi: 10.1016/j.bspc.2014.08.002
C. Sánchez, A. Bueno-Orovio, E. Wettwer, S. Loose, U. Ravens, E. Pueyo, B. Rodríguez (2014). Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation. PLOS ONE, Vol. 9, n.8, e105897, doi:10.1371/journal.pone.0105897
F. Sandberg, R. Bailon, D. Hernando, P. Laguna, J.P. Martinez, K. Solem, L. Sörnmo, (2014) Prediction of hypotension in hemodialysis patients. Physiological Measurement. vol. 35, pp. 1885--1898; doi:10.1088/0967-3334/35/9/1885,
A. Mincholé, E Zacur, E. Pueyo, P. Laguna (2014). Modeling and Quantification of Repolarization Feature Dependency on Heart Rate. Selected paper for the Special 2013 issue of methods of information in medicine, vol. 53, n. 4, pp. 324-8. doi: 10.3414/ME13-02-0040.
A. Alcaine, D. Soto-Iglesias, M. Calvo, E. Guiu, D. Andreu, J. Fernández-Armenta, A. Berruezo, P. Laguna, O. Camara and J. P. Martínez (2014) A Wavelet-Based Electrogram Onset Delineator for Automatic Ventricular Activation Mapping. IEEE Trans. on Biomedical Engineering. v. 61, n. 12, pp. 2830-2839, doi:10.1109/TBME.2014.2330847
L. PB Meijs, L. Galeotti, E. Pueyo, D. Romero, R. B Jennings, M. Ringborn, S.G. Warren, G. S. Wagner, D. G Strauss (2014). An Electrocardiographic Sign of Ischemic Preconditioning. Am J Physiol Heart Circ Physiol. Vol. 307 no. H80-H87DOI: 10.1152/ajpheart.00419.2013
P. Laguna, L. Sörnmo (2014). The STAFF III ECG Database and its Significance for Methodological
Development and Evaluation, Journal of Electrocardiology, n.47; pp. 408–417 doi:10.1016/j.jelectrocard.2014.04.018.
M. M. Demidova, A. Martín-Yebra, J. van der Pals, S. Koul, D. Erlinge, P. Laguna, J. P. Martínez, P. G. Platonov (2014) Transient and rapid QRS widening associated with J-wave pattern predicts impending ventricular fibrillation in experimental myocardial infarction. Heart Rythm. n. 11; pp. 1195–1201 http://dx.doi.org/10.1016/j.hrthm.2014.03.048.
M. P. Bonomini, S. Corizzo, P. Laguna and P. D. Arini (2014) 2D ECG differences in Frontal vs Preferential planes in patients referred for percutaneous transluminal coronary angioplasty. Biomedical Signal Processing, & Control, vol. 11, pp 97-106 doi: 10.1016/j.bspc.2014.01.006
P. D. Arini, F. H. Baglivo, J. P. Martínez and P. Laguna (2014). Evaluation of Ventricular Repolarization Dispersion During Acute Myocardial Ischemia: Spatial and Temporal ECG indices, Medical & Biological Enginering & Computing, Vol. 52, n. 4, pp. 375-391, doi: 10.1007/s11517-014-1136-z
J. Bolea, P. Laguna, J. M. Remartínez, E. Rovira, A. Navarro, R. Bailón. (2014) Methodological framework for estimating the Correlation Dimension in HRV signals. Computational and Mathematical Methods in Medicine. Vol. 2014, Article ID 129248, 11 pages doi:10.1155/2014/129248
M. Orini, B. Hanson, V. Monasterio, J.P. Martínez, M. Hayward, P. Taggart, P. Lambiase (2014). Comparative Evaluation of Methodologies for T-wave Alternans Mapping in Electrograms, IEEE Trans. on Biomedical Engineering. Vol. 61, n. 2. pp. pp. 308-316. doi: 10.1109/TBME.2013.2289304,
A Roebuck, V Monasterio, E Gederi, M Osipov, J Behar, A Malhotra, T Penzel, G D Clifford (2014), A review of signals used in sleep analysis. Physiological Measurement. vol. 35 R1–R57 doi:10.1088/0967-3334/35/1/R1.
J. Lázaro, E. Gil, J. M. Vergara, P. Laguna (2014). Pulse Rate Variability Analysis for Discrimination of Sleep-Apnea-Related Decreases in the Amplitude Fluctuations of PPG Signal in Children, IEEE Journal of Biomedical and Health Informatics, Vol. 18, n. 1, pp. 240-246. doi: 10.1109/JBHI.2013.2267096
A. Bueno-Orovio, C. Sánchez, E. Pueyo, B. Rodriguez (2014). Na/K pump regulation of cardiac repolarization: insights from a systems biology approach. Eur J Physiol. INVITED REVIEW. 466:183–193 doi: 10.1007/s00424-013-1293-1
R. Almeida1, H. Gonçalves, J. Bernardes,and A.P. Rocha (2014). Fetal QRS detection and heart rate estimation: a wavelet-based approach. Physiol. Meas. n. 35 pp. 1723–1735. doi:10.1088/0967-3334/35/8/1723
J. Vicente, L. Johannesen, L. Galeotti, and D. G. Strauss, S. Spring (2014) Mechanisms of sex and age differences in ventricular repolarization in humans. American Heart Journal V. 168, n. 5; pp. 749-756. doi: 10.1016/j.ahj.2014.07.010

Conference Proceedings

M. M. Demidova, A. Martín-Yebra, J. van der Pals, S. Koul, D. Erlinge, P. Laguna, J. P. Martínez, P. G. Platonov (2014) Dynamic QRS-Widening and Appearance of Early Repolarization Pattern Predict
Impending Ventricular Fibrillation in Experimental Myocardial Infarction. American Collegue of Cardiology conference.
A. Martín-Yebra, E. G. Caiani, V. Monasterio, A. Pellegrini, P. Laguna and J. P. Martínez (2014) T-Wave Alternans and Autonomic Nervous System Activity During Orthostatic Stress after 5 Days of Head-Down Bed-Rest. 8th CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS. pp. 115-116.
J. Lázaro, Y. Nam, E. Gil, P. Laguna, and K. H. Chon (2014) Smartphone-Camera-Acquired Pulse Photoplethysmographic Signal for Deriving Respiratory Rate. 8th CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS. pp. 121-122.
G. Valenza, M. Orin. L. Citi, A. Minchole, E. Pueyo, P. Laguna, R. Barbieri, (2014). Assessing Instantaneous QT Variability dynamics within a Point-Process Nonlinear Framework. 8th CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS. pp. 67-68.
A Alcaine, A. Arenal, P. Laguna, and J. P. Martínez (2014) Study of Electrogram Organization and Synchronization in Paroxysmal and Persistent/Permanent Atrial Fibrillation. 8th CONFERENCE OF THE EUROPEAN STUDY GROUP ON CARDIOVASCULAR OSCILLATIONS. pp. 93-94.
J. Bolea1, E. Pueyo, P. Laguna and R. Bailón (2014). Non-linear HRV indices under autonomic nervous system blockade. 36nd Annual International Conference of the IEEE EMBS. Chicago, USA, 2014 pp. 3252-3255.
G. Valenza, M. Orin. L. Citi, A. Minchole, E. Pueyo, P. Laguna, R. Barbieri, (2014). Assessing Real-Time RR-QT Frequency-Domain Measures of Coupling and Causality through Inhomogeneous Point-Process Bivariate Models. 36nd Annual International Conference of the IEEE EMBS. Chicago, USA, 2014 pp. 6475-6478.
J. Carro, J. F. Rodríguez, E. Pueyo (2014) In Silico Simulations of Experimental Protocols for Cardiac Modeling.
36nd Annual International Conference of the IEEE EMBS. Chicago, USA, 2014 pp. 5695-5698.
A. Alcaine, D. Soto-Iglesias, D. Andreu, J. Acosta, A. Berruezo, P. Laguna, O. Camara, J. P. Martínez (2014). A Morphology-Based Spatial Consistency Algorithm to Improve EGM Delineation in Ventricular Electroanatomical Mapping XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 125-128.
D. Romero, N. Behar, A. Martín-Yebra, J. P. Martínez, P. Laguna, E. Pueyo, G. Carrault, P. Mabo, A. Hernández (2014). Analysis of QRS Alterations during Stress Test Recordings on Patients with Brugada Syndrome. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 137-140.
J. Ramírez, I. Cygankiewicz, P. Laguna, M. Malik, E. Pueyo (2014). Circadian Pattern and Sex Differences of QT/RR and T-peak-to-end/RR Curvatures and Slopes in Chronic Heart Failure Patients. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 173-176.
J. Lázaro, R. Bailón, P. Laguna, Y. Nam, K. Chon, E. Gil (2014). Respiratory Rate Influence in the Resulting Magnitude of Pulse Photoplethysmogram Derived Respiration Signals. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 289-192.
P. D. Cruces, M. P Bonomini, M. J. Teperino, A. Mincholé, P. Laguna, P. D. Arini (2014). Normal Ventricular Repolarization Dispersion Range with Abrupt Heart Rate Changes. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 377-380.
D. Romero, J. P. Martínez, P. Laguna, E. Pueyo (2014). Detection of Acute Ischemia Episodes from QRS Angles Changes using a Laplacian Noise Model. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 629-632.
M. Llamedo, J. P. Martínez, P. Laguna (2014). A Pattern-Recognition Approach for Lead-Selection in Heartbeat Detection. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 721-724.
G. Lenis, Y. Lutz, G. Seemann, A. García-Alberola, J. L. Rojo-Ávarez, O. Baquero-Pérez, E. Gil, O. Doessel (1014). Post Extrasystolic TWave Change in SubjectsWith Structural Healthy Ventricles Measurement and Simulation. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 1069-1072.
M. Llamedo, J. P. Martínez (2014). QRS Detectors Performance Comparison in Public Databases. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 357-360.
D. Hernando, R. Bailón, R. Almeida, A. Hernández (2014) QRS Detection Optimization in Stress Test Recordings using Evolutionary Algorithms. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 737-740
L. Johannesen, J. Vicente, C. G. Scully, L. Galeotti, D. G. Strauss (2014). Robust Algorithm to Locate Heart Beats from Multiple Physiological Waveforms. XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 277-280.
A.P. Rocha, R. Almeida, A. Leite, M.J. Silva, M.E. Silva (2014). Long-term HRV in critically ill pediatric patients: comma versus brain death, XLI International Conference on Computing in Cardiology. Cambridge, USA, pp. 89-92.
J Vicente, L Johannesen, RK Afoakwa, E Pueyo, N Stockbridge, J. W. Mason, D. G. Strauss (2014) T wave Morphology Assessment in a Randomized Double-blind Crossover Study of Four hERG Potassium Channel Blocking Drugs, Circulation 130 (Suppl 2), A14051-A14051
V. Monasterio, J. Carro, E. Pueyo (2014). Repolarization alternans in human ventricular hyperkalaemic tissue: dependence on current stimulation. pp. 1-4 Proceedings XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-617-2446-8.
J. Lázaro, R. Bailón, P. Laguna, E. Gil, (2014). Influencia de la Tasa Respiratoria en la Magnitud Resultante de
las Señales Respiratorias Obtenidas de la Señal PPG. pp. 1-4 Proceedings XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-617-2446-8.
J. Ramírez, P. Laguna, E. Pueyo (2014). Modulación Circadiana y de Género de las Relaciones QT/RR y T-pico-a-fin/RR en Pacientes con Insuficiencia Cardiaca. pp. 1-4 Proceedings XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-617-2446-8.
A. Hernando, D. Hernando, N. Garatachea, R. Bailón (2014) Characterization of cardiolocomotor coupling in heart rate variability during exercise test. pp. 1-4 Proceedings XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-617-2446-8.
A. Alcaine, D. Soto, D. Andreu, J. Acosta, A. Berruezo, P. Laguna, O. Cámara, J. P. Martínez, (2014) Algoritmo de consistencia espacial basado en la morfología del electrograma para mejorar la delineación durante mapeo electroanatómico ventricular pp. 1-4 Proceedings XXXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN: 978-84-617-2446-8.

Ph.D. Thesis

Sanchez C. (2014) Multiscale Analysis of Atrial Fibrillation Mechanisms. Zaragoza University

2013

Journals and Books

M. Pelaez, M. Orini, J. lazaro, R. Bailon, E. Gil. (2103) Cross Time-Frequency Analysis for Combining Information of Several Sources. Application to estimation of Spontaneous respiratory rate from Photoplestimography, Computational and Mathematical methods in medicine, Volume 2013, Article ID 631978, 8 pages doi:10.1155/2013/631978
G.Caiani, A. Pellegrini, J. Bolea, M. Sotaquira, R. Almeida, P.Vaïda (2013) Impaired T wave amplitude adaptation to heart-rate induced bycardiac deconditioning after 5-days of head-down bed-rest. Acta Astronautica vol. 91 pp. 166–172
Santos-Lozano A, Santín-Medeiros F, Cardon G, Torres-Luque G, Bailón R, Bergmeir C, Ruiz JR, Lucia A, Garatachea N (2013) . Actigraph GT3X: Validation and Determination of Physical Activity Intensity Cut Points. International Journal of Sports Medicine, DOI: 10.1055/s-0033-1337945
V. Monasterio, J. P. Martínez, P. Laguna, S. McNitt, S. Polonsky, A.J. Moss, M. Haigney, W. Zareba, J.
P. Couderc (2013) Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients, Journal of Electrocardiology, vol. 46, pp. 480-486. doi: 10.1016/j.jelectrocard.2013.08.004
E. Gil, P. Laguna J.P. Martínez, O. Baquero, A. García, L. Sörnmo, (2013). Heart Rate Turbu-lence measured from Photoplethysmography ,IEEE Trans. on Biomedical Engineering, Vol. 60, n.. 11, pp. 3149-3155, doi: 10.1109/TBME.2013.2270083.
E. Pueyo, R. Bailón, E. Gil, J. P. Martínez and P. Laguna (2013). Signal processing guided by physiology: making the most of cardio-respiratory signals , IEEE Signal Processing Magazine, vol.30, n.5, pp. 136-142; doi:10.1109/MSP.2013.2266961.
E. Pueyo (2013). Coronary artery disease diagnosis by analysis of ECG depolarization, Journal of Electrocardiology, vol. 46, pp. 27–28, doi:10.1016/j.jelectrocard.2012.10.016
D. Romero, P. Laguna , E. Pueyo (2013). Detecting acute myocardial ischemai by evaluation of QRS
angles, International Journal of Bioelectromagnetism vol. 15, n.1 pp. 77-82.
M. Demidova, A. Martin-Yebra; J.P. Martinez, V. Monasterio; S. Koul, Jesper van der Pals, D. Romero; P. Laguna, D. Erlinge, P. G. Platonov, (2013). T-wave alternans in experimental myocardial infarction: time course and predictive value for the assessment of myocardial damage, Journal of Electrocardiology, vol. 46 pp. 263– 269. doi:10.1016/j.jelectrocard.2013.03.001
D. Romero, M. Ringborn, P. Laguna and E. Pueyo, (2013) Detection and quantification of acute myocardial ischemia by morphologic evaluation of QRS changes by an angle-based method. Journal of Electrocardiology, vol. 46 pp. 204– 214. doi:10.1016/j.jelectrocard.2013.02.014
R. Bailón, N. Garatachea, I. de la Iglesia, J.A. Casajús, and P. Laguna, (2013). Influence of running stride frequency in heart rate variability analysis during treadmill exercise testing, IEEE Trans. on Biomedical Engineering, Vol. 60, NO. 7, pp. 1796-1805, doi:0.1109/TBME.2013.2242328
J. Lazaro, E. Gil, R. Bailón, A. Mincholé, and P. Laguna, (2013) Deriving Respiration from Photoplethysmographic Pulse Width, Medical & Biological Engineering & Computing. vol. 51 pp. 233– 242. doi:10.1007/s11517-012-0954-0
J. Lazaro, E. Gil, R. Bailón, A. Mincholé, and P. Laguna, (2013) Erratum to: Deriving respiration from photoplethysmographic pulse width, Medical & Biological Engineering & Computing. 51:243 doi: 10.1007/s11517-012-0997-2

Conference Proceedings

C. Sanchez, A. Bueno-Orovio, E. Pueyo, B. Rodriguez (2013) Cell Repolarization Variability Modulates Atrial FibrillationDynamics in 3D Virtual Human Atria XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 911-914.
J. F. Rodriguez, R. Sassi, E. Pueyo, L. Mainardi (2013) Repolarization Variability Mechanisms and its Relation with Cardiac Arrhytmogenesis XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 341-344.
J. Lázaro, A. Alcaine, D. Romero, E. Gil, P. Laguna, L. Sörnmo, R. Bailón (2013) Electrocardiogram Derived Respiration from QRS Slopes: Evaluation with Stress Testing Recordings XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 655-658.
J. M. Remartínez, R. Bailón, E. M. Rovira, J. Bolea, P. Laguna, A. Navarro (2013) Heart Rate Variability Analysis for the Prediction of Hypotension during Spinal Anesthesia in Programmed Cesarean Surgery and its Relation with Fetal Cord Acid-base Equilibrium XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 1231-1234.
F. Sandberg, R. Bailón, D. Hernando, P. Laguna, J. P. Martínez, K. Solem, L. Sörnmo (2013) Prediction of Intradialytic Hypotension using PPG and ECG XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 1227-1230.
R. Jané, J. Lazaro, P. Ruiz, E. Gil, D. Navajas, R. Farré, P. Laguna (2013) Obstructive Sleep Apnea in a Rat Model: Effects of Anesthesia on Autonomic Evaluation from Heart Rate Variability Measures XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 1011-1014.
A. Arza, J. Lázaro, E. Gil, P. Laguna, J. Aguiló, R. Bailon (2013) Pulse Transit Time and Pulse Width as Potential Measure for Estimating Beat-to-Beat Systolic and Diastolic Blood Pressure XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 887-890.
A. Alcaine, D. Soto-Iglesisas, D. Andreu, J. Fernández-Armenta, A. Berruezo, P. Laguna, O. Camara, J. P. Martínez (2013) Wavelet-Based Electrogram Onset Identification for Ventricular Electroanatomical Mapping XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 615-618.
V. Monasterio, J. P. Martínez, S. McNitt, P. Laguna, A. J Moss, W. Zareba, J.-P. Couderc (2013) T-wave Alternans Predicts ICD Discharge in MADIT II Patients with Elevated Resting Heart Rate XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 603-606.
M. Llamedo, J. P. Martínez, M. Albertal, D. Romero, E. Pueyo, P. Laguna (2013) Morphologic Features of the ECG for Detection of Stress-Induced Ischemia XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 591-594.
R. Sassi, L. T Mainardi, P. Laguna, J. F. Rodriguez (2013) Validation of the V-index through Finite Element 2D Simulations XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 337-340.
M. Llamedo, A. Martín-Yebra, P. Laguna, J. P. Martínez (2013) Noninvasive Fetal ECG Estimation Based on Linear Transformations XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 285-288.
E. Grigonytė, E. Gil, P. Laguna, L. Sörnmo (2013) Relative Peripheral Blood Volume Changes in Response to Ventricular Premature Beats during Dialysis XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 209-221.
A. Martín-Yebra, M. Demidova, P. Platonov, P. Laguna, J. P. Martínez (2103) Increase of QRS Duration as a Predictor of Impending Ventricular Fibrillation during Coronary Artery Occlusion XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 133-136.
E. F. Sierra, L.M. Sepúlveda, R. Bailón, P. Laguna, G. Castellanos (2013) Estimating Respiratory Frequency from Heart Rate Variability during Treadmill Exercise Testing, XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 121-124.
D. Hernando, A. Alcaine, E. Pueyo, P. Laguna, M. Orini, A. Arcentales, B. Giraldo, A. Voss, A. Bayés-Genís, R. Bailón (2013) Influence of Respiration in the Very Low Frequency Modulation of QRS slopes and Heart Rate Variability in Cardiomyopathy Patients XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 117-120.
J. Bolea, E. G. Caiani, P. Laguna, R. Almeida (2013), The Linear Dependence of Ventricular Repolarization Variability on Heart Rate Variability in Head-Down Bed Rest Studies. XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 77-80.
J. Ramírez, A. Mincholé, J. Bolea, P. Laguna, E. Pueyo (2013) Prediction of Sudden Cardiac Death in Chronic Heart Failure Patients by Analysis of Restitution Dispersion, XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 1-4.
R. Almeida, A..P Rocha, M.J. Silva (2013). Exploring QT Variability Dependence from Heart Rate in Coma and Brain Death on Pediatric Patients”, XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 61-64.
R. Almeida, H. Gonçalves A.P. Rocha, J. Bernardes (2013), A Wavelet-Based Method for Assessing Fetal Cardiac Rhythms from Abdominal ECGs. XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 289-292.
N Marques, AP Rocha, R Almeida, M Coimbra (2013). Exploring the stationary wavelet transform detail coefficients for the detection and identification of the S1 and S2 heart sounds, XL International Conference on Computing in Cardiology. Zaragoza, Spain, pp. 892-894.
D. Hernando, A. Alcaine, P. Laguna, E. Pueyo and R. Bailón (2013) Very low frequency modulation in QRS slopes and its relation with respiration and heart rate variability during hemodialysis, 35nd Annual International Conference of the IEEE EMBS. Osaka, Japan, 2013 pp. 5365-5368.
J. Lázaro, A. Alcaine, E. Gil, P. Laguna and R. Bailón (2013) Electrocardiogram Derived Respiration from QRS Slopes, 35nd Annual International Conference of the IEEE EMBS. Osaka, Japan, 2013 pp. 3913-3916.
M. Orini, B. Hanson, P. Taggart and P. Lambiase1 (2013) Detection of Transient, Regional Cardiac Repolarization Alternans by Time-Frequency Analysis of Synthetic Electrograms, 35nd Annual International Conference of the IEEE EMBS. Osaka, Japan, 2013 pp. 3773-3776.
M.M. Demidova, J.P. Martínez, A. Martín-Yebra, V. Monasterio, S. Koul, J. van der Pals, P. Laguna, D. Erlinge, P.G. Platonov(2013) T wave alternans in experimantal myocardial infarction: Time-course and preditive value for the assessing of myocardial damage, 62nd Annual Scientific Session of the American College of Cardiology, San Francisco, 9-11 Marzo, 2013. Abstract en Supplement of Journal of the Amercian College of Cardiology, 61(10):E164.
J. Marcos, P. Teperino D. Cruces, A. Minchol´e, P. Laguna , M. P. Bonomini, P. D. Arini. (2013). Dynamic response of temporal and spatial ventricular repolarization dispersion indices during abrupt heart rate changes. XV Reunión de Trabajo en Procesamiento de la Información y Control. Argentina.
J. Bolea, R. Bailón, E. Rovira, J.M. Remaríınez, P. Laguna , A. Navarro (2013). Heart Rate Variability in Pregnant Women before Programmed Cesarean Intervention. XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013, XXXI Congreso Anual de la Sociedad Española de Ingeniería Biomédica.
J. Bolea, P. Laguna, E.G. Caiani, R.Almeida (2013). Heart rate and ventricular repolarization variabilities interactions modification by microgravity simulation during head-down bed rest test. IEEE International Symposium on Computer-Based Medical Systems
M. J. Teperino, P. D. Cruces, A. Mincholé, P. Laguna, M. P. Bonomini, P. D. Arini (2013). Dynamic response of temporal and spatial ventricular repolarization dispersion indices during abrupt heart rate changes. XV Reunion de Trabajo en Procesamiento de la Información y Control, septiembre de 2013

Ph.D. Thesis

Romero D. (2013). Characterization, detection and quantification of acute myocardial ischemia from depolarization ECG-derived indices. Zaragoza University

2012

Journals and Books

R. L. Verrier, T. Klingeheben, M. Malik, N. El-Sherif, D. V. Exner, S. H. Hohnloser, T. Ikeda, J. P. Martínez, S. Narayan, T. Nieminen, D. Rosenbaum (2012). Microvolt T-wave alternans testing has a role in arrhythmia risk stratification. Journal of the American College of Cardiology 59(17):1572-3. April 2012. doi: 10.1016/j.jacc.2012.03.008
M. Orini, R. Bailón, P. Laguna, L. Mainardi, R. Barbieri (2012). A multivariate time-frequency method to characterize the influence of respiration over heart period and arterial pressure, EURASIP Journal on Advances in Signal Processing, 2012 2012:214., doi:10.1186/1687-6180-2012-214
L. Sörnmo, F. Sandberg, E. Gil, K. Solem (2012) Noninvasive Techniques for Prevention of Intradialytic Hypotension. IEEE reviews in Biomedical Engineering. doi: 10.1109/RBME.2012.2210036
V. Monasterio, F. Burgess, G. D. Clifford. Robust classification of neonatal apnoea-related desaturations. Physiological Measurement. vol. 33, pp. 1503–1516, doi:10.1088/0967-3334/33/9/1503
M. Llamedo, and J. P. Martínez. (2012) An Automatic Patient-Adapted ECG Heartbeat Classifier allowing Expert Assistance. IEEE Trans Biomedical Enginiering, vol. 59, n. 8, doi: 10.1109/TBME.2012.2202662
M. Llamedo, A. Khawaja, and J. P. Martínez. (2012) Cross-Database Evaluation of a Multilead Heartbeat Classifier. IEEE Transactions on Information Technology in Biomedicine. vol. 16, n. 4, pp. 658-664. doi: 10.1109/TITB.2012.2193408
M. Noriega, J.P. Martínez, P. Laguna, R. Bailón and R. Almeida (2011). Respiration effect on Wavelet-based ECG T-wave end delineation strategies. IEEE Trans Biomedical Enginiering, Vol. 59, N. 7, pp. 1818-1828 doi: 10.1109/TBME.2011.2157824
V. Monasterio, P. Laguna, I. Cygankiewicz, R. Vázquez, A. Bayés-Genís, A. Bayés de Luna, JP. Martínez (2012). Average T-wave alternans activity in ambulatory ECG records predicts sudden cardiac death in patients with chronic heart failure. Heart Rhythm, Vol. 9, n 3, pp. 383-389. doi: 10.1016/j.hrthm.2011.10.027
V. Monasterio, P. Laguna, I. Cygankiewicz, R. Vázquez, A. Bayés-Genís, A. Bayés de Luna, JP. Martínez (2012) Average T-wave alternans activity in ambulatory electrocardiogram records: Commentary on the relationship with T-wave amplitude and T-wave alternans regionality Heart Rhythm, Vol 9, No 3, e6-e7, doi:10.1016/j.hrthm.2011.11.05
C. Sánchez, A. Corrias, A. Bueno-Orovio M. Davies, J. Swinton, I. Jacobson, P. Laguna, E. Pueyo, B. Rodríguez. The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue, Am J Physiol Heart Circ Physiol, 302: H1146--H1159. doi:10.1152/ajpheart.00668.2011.
M. Orini, P. Laguna, L. Mainardi, R. Bailón (2012). Assessment of the dynamic interactions between heart rate and arterial pressure by cross time-frequency analysis. Physiological Measurement, vol. 33, pp. 315-331. doi:10.1088/0967-3334/33/3/315
M. Orini, R. Bailón, L. Mainardi, P. Laguna. (2012) Synthesis of HRV signals characterized by predetermined time-frequency structure by means of time-varying ARMA models. Biomedical Signal Processing and Control, vol. 7, pp. 141-150 doi:10.1016/j.bspc.2011.05.003
M. Orini, R. Bailón, L. Mainardi, P. Laguna, P. Flandrin (2012). Characterization of the dynamic interactions between cardiovascular signals by time-frequency coherence, IEEE Trans Biomedical Engineering, vol. 59, n. 3, pp. 663-673, doi:10.1109/TBME.2011.2171959
D. Romero, M. Ringborn, M. Demidova, P. Laguna, S. Koul, P. Platonov, E. Pueyo (2012). Characterization of Ventricular Depolarization Changes in a Porcine Model of Myocardial Infarction, Physiological measurement, vol 33 1975--1991 doi:10.1088/0967-3334/33/12/1975

Conference Proceedings

Garde, P. Laguna, B. F. Giraldo, R. Jane, L. Sornmo (2012) Ensemble-based time alignment of biomedical signals (BSI12), Como, . Julio. 2012.
Romero, P. Laguna, E. Pueyo, (2012) Detecting acute myocardial ischemia by evaluation of qrs angles (BSI12), Como, . Julio. 2012.
M. Orini, P. Laguna, L. T. Mainardi, R. Bailon (2012) Influence of music emotional valence on cardio-respiratory coupling (BSI12), Como, . Julio. 2012.
Minchole, E. Zacur, E. Pueyo, P. Laguna (2012) Robust characterization of repolarization adaptation to heart rate changes (BSI12), Como, . Julio. 2012.
A. Minchole, A. Bueno-Orovio, P. Laguna, E. Pueyo, B. Rodriguez, (2012) A novel ecg-based biomarker quantifying apd restitution dispersion improves risk stratification following sotalol administration (BSI12), Como, . Julio. 2012.
J. Bolea, E. G. Caiani, E. Pueyo, P. Laguna and R. Almeida (2012) Microgravity effects on ventricular response to heart rate changes, 34nd Annual International Conference of the IEEE EMBS. San Diego, USA, 2012 pp. 3424-3427.
M. Orini, L. Citi, R. Barbieri, (2012) Bivariate point process modeling and joint non-stationary analysis of pulse transit time and heart period 34nd Annual International Conference of the IEEE EMBS. San Diego, USA, , 2012 pp. 2831-2834.
J. Daly1, V. Monasterio, G. D. Clifford1 (2012), A Neonatal Apnoea Monitor for Resource-Constrained Environments. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 321-324.
C. Sánchez, MW Krueger, G Seemann, O Dössel, E Pueyo, B Rodríguez (2012), Ionic Modulation of Atrial Fibrillation Dynamics in a Human 3D Atrial Model. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 137-140.
M. Orini, G. Valenza, L. Citi, R. Barbieri (2012), Tetravariate Point-Process Model for the Continuous Characterization of Cardiovascular-Respiratory Dynamics during Passive Postural Changes. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 273-276.
A. Alcaine, F. Simón, A. Arenal, P Laguna, J. P. Martínez (2012) A Wavelet-Based Activation Detector for Bipolar Electrogram Analysis During Atrial Fibrillation. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 717-720.
J. Raíırez, A. Mincholé, P. Laguna, E. Pueyo (2012) Characterization of Cardiac Repolarization Response to Heart Rate Changes Provoked by a Tilt Test. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 673-676.
A. Cabasson, O. Meste, R. Bailón, P. Laguna (2012). Validation of the PR-RR Hysteresis Phenomenon. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 597-600.
L. Canga, A. Navarro, J. Bolea, J. M Remartínez, P. Laguna, R. Bailón (2012). Non-Linear Analysis of Heart Rate Variability and its Application to Predict Hypotension during Spinal Anesthesia for Cesarean Delivery. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 413-416.
A. Martín-Yebra, V. Monasterio, A. Pellegrini, P. Laguna, E. Caiani, J. P. Martínez (2012). Effect of Simulated Microgravity by Head-Down Bed Rest on TWave Alternans. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 377-380.
J. Lázaro, E. Gil1, J. M. Vergara, P. Laguna (2012) OSAS Detection in Children by using PPG Amplitude Fluctuation Decreases and Pulse Rate Variability. XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 185-188.
A Pellegrini, J Bolea, M Llamedo, M Sotaquira, R Almeida, P Laguna, P Vaïda, EG Caiani (2012). Selective Beat Averaging to Evaluate Ventricular Repolarization Adaptation to Deconditioning after 5 Days of Head-Down Bed Rest XXXIX International Conference on Computing in Cardiology. Kracow, Poland, pp. 605-608.
L. PB Meijs, L. Galeotti, E. Pueyo, D. Romero, R. B Jennings, G. S. Wagner, D. G Strauss.(2012) Increased T-amplitude with decreased ST-elevation characterizes ischemic preconditioning: A Simulation, Experimental and Clinical Study, ISCE 2012 Annual Meting, Harrisburg (USA)
E.G. Caiani , A. Pellegrini, J. Bolea, M. Sotaquira, M. Llamedo, R. Almeida, P. Laguna, P. Vaida (2012) Impaired T-wave amplitude adaptation to heart-rate induced by cardiac deconditioning after 5-days of head-down bed-rest. 63rd International Astronautical Congress Naples, Italy
C. Sánchez, A. Bueno-Orovio, E. Pueyo, B. Rodríguez (2012). Analysis of Populations of Human Atrial Models Reveals the Relative Importance of Ionic Conductances in the Different Stages of Repolarization”. 36th meeting of the European Working Group of Cardiac Cellular Electrophysiology, Nantes (France), Septiembre 2012, in press.
E. Gil, P. Laguna, J.P. Martínez, L. Sörnmo (2012) Pulse rate analysis from the photoplethysmographic signal for turbulence detection. In Lectures Notes of the ICB Seminars, International Centre of Biocybernetics, Polish Academy of Science. Warsaw (Poland)
A. Alcaine , F. Simón, Á. Arenal, P. Laguna, J.P. Martínez (2012). Detector de Activaciones Basado en Wavelet para el Análisis de Electrogramas Bipolares Durante Fibrilación Auricular. Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN – 10:84-616-2147-6; ISBN – 13:978-84-616-2147-7
D. Hernando, R. Bailón, P. Laguna, L. Sörnmo (2012) Clasificación de pacientes propensos y resistentes a hipotensión durante hemodiálisis a partir de la variabilidad del ritmo cardiaco y la presión sanguínea Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN – 10:84-616-2147-6; ISBN – 13:978-84-616-2147-7
J. Lázaro, E. Gil, J. M. Vergara, P. Laguna (2012) Detección del SAOS en Niños mediante los Descensos de las
Fluctuaciones de Amplitud en la Señal PPG y la Variabilidad de Ritmo de Pulso Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN – 10:84-616-2147-6; ISBN – 13:978-84-616-2147-7
J. Ramírez, A. Mincholé, P. Laguna, E. Pueyo (2012) Caracterización de la Respuesta de la Repolarización a Cambios en el Ritmo Cardiaco Provocados por una Prueba de “Tilt” Proceedings XXX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. ISBN – 10:84-616-2147-6; ISBN – 13:978-84-616-2147-7
J. Bolea, R. Almeida, E. Pueyo, P. Laguna, E. Caiani, (2012) Ventricular Repolarization Adaptation to Abrupt Changes in Heart Rate after Microgravity Simulation by 5‐days Head‐Down Bed Rest. Life in Space for Life on Earth, 12th European life Science symposium, Aberdeen.

Ph.D. Thesis

Llamedo M. (2012). Signal Processing for Automatic Heartbeat Classification and Patient Adaptation in the Electrocardiogram. Zaragoza University

2011

Journals and Books

R. L. Verrier, T. Klingeheben, M. Malik, N. El-Sherif, D. V. Exner,, S. H. Hohnloser, T. Ikeda, J. P. Martínez, S. Narayan, T. Nieminen, D. Rosenbaum (2011). Microvolt T-Wave Alternans Physiological Basis, Methods of Measurement, and Clinical Utility—Consensus Guideline by International Society for Holter and Noninvasive Electrocardiology. Journal of the American College of Cardiology 2011;58:1309–1324. doi:10.1016/j.jacc.2011.06.029
M. Llamedo, J. P. Martínez. (2011) Heartbeat Classification Using Feature Selection driven by Database Generalization Criteria IEEE Transactions on Biomedical Engineering, 2011, 58, 616-625. doi:10.1109/TBME.2010.2068048 Marzo. 2011
T. Mar, S. Zaunseder, J. P. Martínez, M. Llamedo, and R. Pol (2011) Optimization of ECG Classification by Means of Feature Selection IEEE Transactions on Biomedical Engineering. Vol. 58, No. 8, pp. 2168- 2177 doi: 10.1109/TBME.2011.2113395
S. Nemati, O. Abdala, V. Monasterio, S. Yim-Yeh, A. Malhotra, and G.D. Clifford (2011) A Nonparametric Surrogate-Based Test of Significance for T-Wave Alternans Detection IEEE Transactions on Biomedical Engineering. Vol. 58, N. 5, pp. 1356- 1364. Digital Object Identifier 10.1109/TBME.2010.2047859
D. Romero, M. Ringborn, P. Laguna, O. Pahlm, E. Pueyo (2011) . Depolarization changes during acute myocardial ischemia by evaluation of QRS slopes. Standard lead and vectorial approach. IEEE Transactions on Biomedical Engineering. Vol. 58, No. 1, pp. 110-120. doi:10.1109/TBME.2010.2076385.
R. Bailón, G. Laouini, C. Grao, M. Orini, P. Laguna, O. Meste (2011). The Integral Pulse Frequency Modulation with Time-Varying Threshold: Application to Heart Rate Variability Analysis during Exercise Stress Testing. IEEE Trans. on Biomedical Engineering, VOL. 58, NO. 3, pp 642-652 10.1109/TBME.2010.2095011
L.M. Sepulveda-Cano, E. Gil, P. Laguna, G. Castellanos-Dominguez (2011). Selection of Non-stationary Dynamic Features for Obstructive Sleep Apnoea Detection in Children. EURASIP Journal on Advances in Signal Processing, Volume 2011, ISSN 1687-6172 Article ID 538314, 10 pages doi:10.1155/2011/538314.
A. Mincholé, E. Pueyo, J.F. Rodríguez, E. Zacur, M. Doblaré and P. Laguna (2011). Quantification of Restitution Dispersion from the Dynamic Changes of the T wave peak to end, measured at the Surface ECG. IEEE Trans Biomedical Enginiering, Vol. 58, n. 5, pp. 1172-1182. doi:10.1109/TBME.2010.2097597
R. Bailon, P. Serrano, P. Laguna (2011). Influence of time-varying mean heart rate in coronary artery disease diagnostic performance of heart rate variability indices from exercise stress testing. Journal of Electrocardiology, vol.44, pp. 445–452, doi:10.1016/j.jelectrocard.2011.02.001
M. Ringborn, D. Romero, E. Pueyo, O. Pahlm, G.S. Wagner, P. Laguna and P.G. Platonov (2011). Evaluation of depolarization changes during acute myocardial ischemia by analysis of QRS slopes. Journal of Electrocardiology, vol. pp. 44 416--424 doi:10.1016/j.jelectrocard.2011.03.005
J. Carro, J.F. Rodriguez, P. Laguna, and E. Pueyo. (2011). A human ventricular cell model for investigation of cardiac arrhythmias under hyperkalemic conditions. Phil Trans Royal Soc A, n. 369, pp. 4205-4232, doi: 10.1098/rsta.2011.0127
E. Pueyo A. Corrias, L. Virág, N. Jost, T. Szel, A. Varró, N. Szentandrássy, P. Nánási, K. Burrage, B. Rodríguez.(2012) A multi-scale investigation of repolarization variability and its role in cardiac arrhythmogenesis. Biophys J, Vol. 101(12), p.2892-2902. doi:10.1016/j.bpj.2011.09.060

Conference Proceedings

L.M. Sepulveda-Cano, E. Gil, P. Laguna, G. Castellanos-Dominguez (2011) Sleep Apnoea Detection in Children using PPG Envelope-Based Dynamic Features. 33nd Annual International Conference of the IEEE EMBS. Boston, USA, August 30 - September 4, 2011 pp. 1483-1486
M. Orini, R. Bailón, L. T. Mainardi and P. Laguna (2011) Time–frequency phase differences and phase locking to characterize dynamic interactions between cardiovascular signals. 33nd Annual International Conference of the IEEE EMBS. Boston, USA, August 30 - September 4, 2011 pp. 4689-4692
S. Gouveia, A. P. Rocha, P. van de Borne and P. Laguna (2011) Factors influencing differences between invasive and spontaneous baroreflex estimates: distinct methods or different data? 33nd Annual International Conference of the IEEE EMBS. Boston, USA, August 30 - September 4, 2011 pp. 2554-2557
A. Mincholé, L. S¨ornmo and P. Laguna (2011) ECG-based detection of body position changes using a Laplacian noise model 33nd Annual International Conference of the IEEE EMBS. Boston, USA, August 30 - September 4, 2011 pp. 6931-6934.
J. Bolea, E. Pueyo, R. Almeida, M. Llamedo, M. Sotaquirб, J. P. Martinez, P Laguna E. G Caiani (2011). Influence of simulated microgravity by Head-Down-Bed-Resting on QT/RR Dynamics. XXXVIII International Conference on Computing in Cardiology. Hangzhou, China, pp. 53-56
J. Vicente, P. Laguna, A. Bartra R. Bailón (2011) Detection of Driver's Drowsiness by Means of HRV Analysis. XXXVIII International Conference onComputing in Cardiology.Hangzhou, China, pp. 89-92.
F. Simón, A. Arenal, P. Laguna, J. P. Martínez(2011). Comparison of EGM Organization and Synchronization Indices in Atrial Fibrillation: a Simulation Study, XXXVIII International Conference on Computing in Cardiology. Hangzhou, China, pp. 181-184.
D. Hernando, R. Bailón, P. Laguna L. Sörnmo (2011) Heart Rate Variability Analysis during Hemodialysis and its Relation with Hypotension, XXXVIII International Conference on Computing in Cardiology. Hangzhou, China, pp. 189-192.
V. Monasterio, P. Laguna, I. Cygankiewicz, J. P. Martínez, (2011). Average T-wave Alternans Activity in Ambulatory ECGs. XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 621-624.
E. Gil, L. Sörnmo P. Laguna (2011). Detection of Heart Rate Turbulence in Photoplethysmographic Signals. XXXVIII International Conference on Computing in Cardiology. Hangzhou, China, pp. 665-668.
J. P. Martínez, A. Martín-Yebra, V. Monasterio, M. Demidova, P. Platonov P. Laguna (2011) Time Course and Spatial Distribution of T Wave Alternans Induced by Artery Occlusion in Pigs. XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 669-672.
J. Lázaro, E. Gil, R. Bailón P. Laguna (2011) Deriving Respiration from the Pulse Photoplethysmographic Signal. XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 713-716.
A. Alcaine, R. Bailón, D. Romero, E. Pueyo, P. Laguna (2011) Very-Low-Frequency Modulation of QRS slopes in Patients with Angina Pectoris. XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 757-760
M. Llamedo J. P. Martínez (2011) Analysis of a Semiautomatic Algorithm for ECG Heartbeat Classification XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 137-140
M. Orini, M. D. Pelaez-Coca, R. Bailón E. Gil (2011) Estimation of the Respiratory Rate from Photoplethysmography by Cross Time-frequency Analysis XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 661-664.
C. Sanchez, B. Rodriguez E. Pueyo (2011) Ionic Modulators of Electrophysiology and Re-entry Properties in Human Atria XXXVIII International Conference on Computing in Cardiology.Hangzhou, China, pp. 77-80
M. Orini, P. Laguna, L. Mainardi, R. Bailón. (2011) Characterization of the dynamic interactions between cardiovascular signals by cross time–frequency analysis: phase differences, time delay and phase locking.Congress on numerical method in engineering, June 14th-17th, Coimbra, Portugal . Junio. 2011.
M. Llamedo, J. P. Martínez (2011) Análisis de un Algoritmo para la Clasificación Semiautomática de Latidos en ECG. Proceedings XXIX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. pp. 33-36.
J. Bolea, E. Pueyo, R. Almeida, M. Sotaquira, M. Llamedo, J.P. Martínez, P. Laguna, E.G. Caiani. (2011) Microgravedad simulada mediante Head-Down-Bed-Resting y su influencia en la dinámica del QT/RR. Proceedings XXIX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. pp. 441-444.
J. Vicente, P. Laguna, A. Bartra, R. Bailon (2011). Análisis HRV en la Detección de Somnolencias en Conductores Proceedings XXIX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. pp. 193-196.
D. Romero, M. Ringborn, E. Pueyo, O. Pahlm, G.S. Wagner, P. Laguna, P. Platanov (2011) Análisis de la despolarización en isquemia de miocardio mediante la evaluación de las pendientes del QRS. Proceedings XXIX Congreso Anual de la Sociedad Española de Ingeniería Biomédica. pp. 41-44.
D. Romero, M. Ringborn, P. Laguna, O. Pahlm, E. Pueyo (2011) Análisis Espacial en la Evaluación de Cambios de la Despolarización Cardíaca durante Isquemia Aguda de Miocardio. V Latin American Congress on Biomedical Engineering CLAIB 2011, pp:1-4

Ph.D. Thesis

Mincholé A. (2011). Automatic detection of ischemia in Holter recordings and search for new risk markes from the electrocardiographic signal. Zaragoza University.
Monasterio V. (2011). Multilead analysis of T-wave alternans in the electrocardiogram. Zaragoza University.
Orini M. (2011). Time-frequency analysis for the dynamic quantification of the interactions between signals related to the cardiovascular system. Zaragoza University/Politecnique of Milan.

2010

Journals and Books

D. Abramson, M. Bernabeu, B. Bethwaite, K. Burrage, E. Pueyo Paules, B. Rodríguez, A. Sher, K. Tan. (2010) High-throughput cardiac science on the grid.Philosophical Transactions of the Royal Society - A. Vol. 368, pp.3907-3923. Mayo .2010.
A. Corrias, X. Jie, L. Romero, M. Bishop, M Bernabeu, E. Pueyo, B. Rodríguez. (2010)Arrhythmic Risk Biomarkers for the Assessment of Drug Cardiotoxicity: from experiments to computer simulations .Philosophical Transactions of the Royal Society - A, Vol. 368, pp.3001-3025.

D. Smith, K. Solem, P. Laguna, J. P. Martínez, L. Sörnmo (2010) Model-based Detection of Heart Rate Turbulence Using Mean Shape Information. IEEE Transactions on Biomedical Engineering, Vol. 57, n. 2, pp. 334-342 .

A. Mincholé, F. jager, P. Laguna (2010). Discrimination Between Ischemic and Artifactual ST Segment Events in Holter Recordings. Biomedical signal processing and control, Vol. 5 pp. 21-31 doi:10.1016/j.bspc.2009.09.001

E. Gil, R. Bailón, J. M. Vergara, P. Laguna (2010). PTT variability for discrimination of sleep apnea related decreases in the amplitude fluctuations of PPG signal in children .IEEE Transaction on Biomedical Engineering, vol. 57, n. 5, pp. 1079-1088, doi:10.1109/TBME.2009.2037734

M. Orini, R. Bailón, R. Enk, S. Koelsch, L. Mainardi, P. Laguna (2010). A method for continuously assessing the autonomic response to music-induced emotions through HRV analysis. Medical and Bilogical Engineering and Computing, 48, pp.423–433, DOI: 10.1007/s11517-010-0592-3

E. Pueyo, Z. Husti, T. Hornyik, I.Baczkó, P. Laguna, A. Varró, B. Rodríguez (2010) Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk, American Journal of Physiology, vol. 298, pp H1577-H1587, doi:10.1152/ajpheart.00936.2009

V. Monasterio, G. D. Clifford, P. Laguna, J. P. Martínez. (2010) A Multilead Scheme based on Periodic Component Analysis for T Wave Alternans Analysis in the ECG. Annals of Biomedical Engineering, Vol. 38, No. 8, pp. 2532–2541; doi: 10.1007/s10439-010-0029-z

M. Orini, R. Bailón Luesma, E. Gil Herrando, L. Minardi, P. Laguna (2010). Framework for continuous quantification of spectral Coherence using Quadratic Time-Frequency distributions: exploring cardiovascular coupling. International Journal of Bioelectromagnetism, , Vol. 12, No. 4, pp. 177-182.

E. Gil, J.M. Vergara, and P. Laguna (2010). Pulse Transit Time Variability versus Heart Rate Variability during Decreases in the Amplitude fluctuations of Photoplethysmography signal. International Journal of Bioelectromagnetism, Vol. 12, No. 3, pp. 95 - 101,

E. Gil, M Orini, R. Bailón, J.M. Vergara, L. Mainardi and P.Laguna (2010). Photoplethysmography pulse rate variability as a surrogate measurement of heart rate variability during non-stationary conditions. Physiological Measurement, vol. 31, pp. 1271-1290 , doi:10.1088/0967-3334/31/9/015

J. P. Martínez, I. Cygankiewicz, D. Smith, A. Bayés de Luna, P. Laguna, L. Sörnm (2010).Detection performance and risk stratification using a model-based shape index characterizing heart rate turbulence. Annals of Biomedical Engineering, Vol. 38, No. 10, pp. 3173-3184.

R. Bailon, L. Mainardi, M. Orini, L. Sörnmo, P. Laguna (2010). Analysis of heart rate variability during exercise stress testing using respiratory information. Biomedical Signal Processing and Control, vol. 5, pp. 299–310, doi:10.1016/j.bspc.2010.05.005.

Conference Proceedings

A. Corrias, E. Pueyo Paules, K. Burrage, B. Rodriguez (2010). Causes of variability in Repolarization: From isolated cells to ECG .31st Annual Conference, Heart Rhythm, V. 7 n. 5 pp. S227. Mayo. 2010.

E. Pueyo (2010) QT/RR adaptation .THEW Newsletter Issue 10. QT evaluation for drugs with autonomic effects (PART II): QT/RR relationship and QT hysteresis. Octubre. 2010.

X. Jie, B. Rodriguez, E. Pueyo (2010). A New ECG Biomarker for DrugToxicity: a Combined Signal Processing and Computational Modeling Study .32nd Annual International Conference of the IEEE EMBS. Buenos Aires, Argentina, August 31-September 4,2010,pp.2565-2568.

M. Llamedo and J. P. Martínez (2010). Evaluation of an ECG Heartbeat Classifier Designed by Generalization-Driven Feature Selection. 32nd Annual International Conference of the IEEE EMBS Buenos Aires, Argentina, pp. 5399-5402

Llamedo, M.; Khawaja, A.; Martinez, J.P.(2010) Analysis of 12-lead classification models for ECG classification, XXXVII International Conference on Computers in Cardiology. Belfast, UK, pp. 673 - 676

V. Monasterio, G.D. Clifford and J.P. Martínez (2010) Comparison of Source Separation Techniques for Multilead T-Wave Alternans Detection in the ECG. 32nd Annual International Conference of the IEEE EMBS Buenos Aires, Argentina, pp. 5367-5370.

M. Blanco, F. Cruz, E. Moreno, J. P. Martínez, P. Amo (2010). Continuous Time Analysis Method for T-Wave Alternans Detection. XXXVII International Conference on Computing in Cardiology;37:757-760 Belfast, U.K. Septiembre.

X. Jie, B. Rodriguez, E. Pueyo (2010) Torsadogenic Drug-Induced Increased Short-term Variability of JT-area .XXXVII International Conference on Computing in Cardiology;37:353-356, Belfast, U.K. Septiembre. 2010.

V. Monasterio, J. P. Martínez (2010) Analysis of T-wave Alternans in Stress Tests with Periodic Component Analysis. 37th International Congress on Electrocardiology. pp.12.

E. Gil, M. Orini, R. Bailón, P. Laguna, J.M. Vergara (2010) . Comparative analysis between PPG variability and HRV during non-stationary tilt table test. 6th Conference of the European Study Group on Cardiovascular Oscillations. Abril. 2010. pp. 1-4

A. Mincholé, E. Pueyo, P. Laguna (2010). Dispersion of APD restitution quantified from the surface ECG. 35th Research and Technology transfer in computerized electrocardiology. Abril 2010. Abril. 2010.

C. Sanchez, A. Corrias, P. Laguna, E. Pueyo, B. Rodriguez (2010). Sensitivity of Atrial Fibrillation Related Biomarkers to changes in Ionic Current Properties. 31st Annual Conference, Heart Rhythm, v. 7; n. 5. pp.S165. . Mayo. 2010.

M. Ringborn, D. Romero, O. Pahlm, G. Wagner, P. Laguna, E. Pueyo, P. Platonov (2010). Analysis of QRS slopes as a measure of depolaritazion change during acute myocardial ischemia. 37th International Congress on Electrocardiology. pp. 151.. Junio. 2010.

R. Bailón, C. Grao, P. Laguna (2010). Discrimination Of Coronary Artery Disease Patients by Means of Heart Rate Variability Analysus During Exercise Stress Testing . 37th International Congress on Electrocardiology. pp. 39 . Junio. 2010.

E. Gil, M. Orini, R. Bailón, J. M. Vergara, L. Mainardi, P. Laguna (2010). Time-varying spectral analysis for comparison of HRV and PPG variability during tilt table test. 32nd Annual International Conference of the IEEE EMBS. Buenos Aires, Argentina, August 31 - September 4, 2010, pp 3579-3582, pp.

M. Noriega, J.P. Martínez, P. Laguna, D. Romero, R. Bailón and R. Almeida (2010). Respiration effect on single and multi lead ECG delineation strategies. 32th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc. Buenos Aires, 2010. pp. 3575-3578.

M. Orini, L. Mainardi, E. Gil, P. Laguna, and R. Bailón (2010). Dynamic assessment of spontaneous baroreflex sensitivity by means of time-frequency analysis using either RR or pulse interval variability. 32th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc. IEEE Engineering in Medicine and Biology Society, Buenos Aires, 2010, pp. 1630-1633.

D. Romero, M. Ringborn, P. Laguna, O. Pahlm, E. Pueyo (2010). A Vectorial Approach for Evaluation of Depolarization Changes during Acute Myocardial Ischemia. XXXVII International Conference on Computers in Cardiology. Belfast, UK, pp. 265-268.

C. Sánchez, A. Corrias, P. Laguna, M. Davies, J. Swinton, I. Jacobson, E. Pueyo, B. Rodríguez (2010) Potential Pharmacological Therapies for Atrial Fibrillation. A Computational Study. XXXVII International Conference on Computers in Cardiology. Belfast, UK, pp. 413-416.

A. Mincholé, E. Pueyo, J.F. Rodríguez, E. Zacur, M. Doblaré and P. Laguna (2010) Evaluation of a Method for Quantification of Restitution Dispersion from the surface ECG. XXXVII International Conference on Computers in Cardiology, Belfast, UK, pp. 773-776.

J. Carro, J.F. Rodríguez, P. Laguna, E. Pueyo (2010) Analysis and Improvement of a Human Ventricular Cell Model for Investigation of Cardiac Arrhythmias, XXXVII International Conference on Computers in Cardiology, Belfast,UK. pp. 817-820.

R. Almeida, J.P. Martínez, A.P. Rocha, P. Laguna, E. Pueyo (2010). P Wave Delineation Using Spatially Projected Leads From Wavelet Transform Loops. XXXVII International Conference on Computers in Cardiology, Belfast, UK, pp. 1003-1006.

S. Gouveia, , A.P. Rocha, P. Laguna,P. Van de Borne (2010) Correlation Between Time Domain Baroreflex Sensitivity and Sympathetic Nerve Activity, XXXVII International Conference on Computers in Cardiology, Belfast, UK pp. 5-8.

E. Cirugeda, M. Orini, P. Laguna, R. Bailón (2010). Respiratory Frequency Estimation From Heart Rate Variability Signals in Non-Stationary Conditions Based on the Wigner-Ville Distribution, XXXVII International Conference on Computers in Cardiology, Belfast, UK 2010, pp. 717-720.

M. Orini, E. Gil Herrando, R. Bailón Luesma, Mainardi, Luca, P. Laguna. Comparison of the TF structure of PPGV and HRV by means of bivariate TF analysis II congresso del gruppo nazionale di bioingegneria (GNB), Torino, Italia. Julio. 2010.

V. Monasterio, G.D. Clifford, J. P. Martínez (2010). Comparación de Técnicas de Separación de Fuentes para la Detección de Alternancias de Onda T en el ECG".XXVIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica.Procesamiento Señales Biomédicas IV, 4.0 D03 pp.163 Noviembre 2010.

M. Llamedo, J. P. Martínez (2010) Desarrollo de un Clasificador de Latidos de ECG con Capacidad de Generalización XXVIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica. Procesamiento Señales Biomédicas V, 4.2, E03. pp. 204.

2009

Journals and Books

L. Romero, E. Pueyo, M. Fink, B. Rodríguez (2009). Impact of ionic current variability on human ventricular cellular electrophysiology.American Journal of Physiology. Vol. 297, pp. 1436-1445. Agosto. 2009.

E. Gil, M. Mendez, J.M. Vergara, S. Cerutti, A. M. Bianchi, P. Laguna (2009). Discrimination of sleep apnea related decreases in the amplitude fluctuations of PPG signal in children by HRV. IEEE Trans. on Biomedical Engineering, vol. 56, n.. 4, pp. 1005-1014.

Laguna P., Sörnmo L (2009). Introduction. Editorial on "Signal processing in vital rhythms and signs". Special issue on Signal processing in vital rhythms and signs, Transactions of the Royal Society A, vol. 367, pp. 207–211. doi:10.1098/rsta.2008.0239.

E. Pueyo, J. P. Martínez, P. Laguna (2009). Cardiac repolarisation analysis using the surface ECG. Philosophical Transactions of the Royal Society - A. vol. 367, pp. 213–233.doi:10.1098/rsta.2008.0230.

V. Monasterio, P. Laguna and J.P. Martínez (2009). Multilead Analysis of T Wave Alternans in the ECG using Principal Component Analysis. IEEE Trans. on Biomedical Engineering, vol.56, no.7, pp.1880-1890. doi:10.1109/TBME.2009.2015935

R. Almeida, J.P. Martínez, A.P. Rocha and P. Laguna (2009). Multilead ECG delineation using spatially projected leads from wavelet transform loops. IEEE Trans. on Biomedical Engineering, vol. 56, no. 8, pp. 1996-2005, doi:10.1109/TBME.2009.2021658

S. Gouveia, A. P. Rocha A. P., P. Laguna and P. Lago (2009). Time domain baroreflex sensitivity assessment by joint analysis of spontaneous SBP and RR series. Biomedical signal processing and control. vol. 4, pp. 254-261 doi:10.1016/j.bspc.2009.03.003

Conference Proceedings

E. Pueyo, A. Corrias, D. Gavaghan, K. Burrage, B. Rodríguez (2009). Effect of stochastic channel gating in cardiac behavior".Gordon Research Conference on Cardiac Arrhythmia Mechanisms.

E. Pueyo, A. Corrias, D. Gavaghan, K. Burrage, B. Rodríguez (2009) Role of stochastic IKs gating kinetics in arrhythmogenesis".Heart Rhythm, 30th Annual Scientific Sessions.

E. Pueyo, A. Corrias, D. Gavaghan, K. Burrage, B. Rodríguez. (2009) Stochastic IKs gating kinetics and their role in arrhythmogenesis".The Cardiac Physiome: Multi-scale and Multi-physics Mathematical Modelling Applied to the Heart.

Z. Husti, T. Hornyik, E. Pueyo, B. Rodríguez, I. Baczkó, A. Varró (2009). The role of different ionic currents in APD adaptation to heart rate changes.33rd meeting of the European Working Group of Cardiac Cellular Electrophysiology.

V. Monasterio, J. P. Martínez (2009). Comparison of two eigenvalue decomposition techniques to detect T Wave Alternans in the ECG.World Congress on Medical Physics and Biomedical Engineering, IFMBE Proceedings 25/IV, pp.631–634.

M. Llamedo, J. P. Martínez (2009). Analysis of Multi Domain Features for ECG Classification. XXXVI Ann. Conf. Computers in Cardiology pp. 561-564.

M. Orini, R. Bailón, E. Gil Herrando, Luca Mainardi, P. Laguna. Framework for continuous quantification of spectral Coherence using Quadratic Time-Frequency distributions: exploring cardiovascular coupling. 6th International Workshop on Biosignal Interpretation (BSI09), New Haven, pp 68-71. Junio. 2009.

E. Gil, J. M. Vergara, P. Laguna. Pulse Transit Time Variability versus Heart Rate Variability during Decreases in the Amplitude fluctuations of Photoplethysmography signal. 6th International Workshop on Biosignal Interpretation (BSI09), New Haven, pp 56-59. Junio. 2009.

C. Sánchez, E. Pueyo, P. Laguna, B. Rodríguez. Cardiac Memory in Human Atria and Relation to Arrhythmogenesis. XXXVI Ann. Conf. Computers in Cardiology, pp. 81-84, Park City. Septiembre. 2009.

F.H. Baglivo, P.D. Arini, J. P. Martínez, P. Laguna. Analysis of T Wave Morphology Parameters with Signal Averaging during Ischemia Induced by Percutaneous Transluminal Coronary Angioplasty. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 689-692. Septiembre. 2009.

R. A. Almeida, J. P. Martínez, A. P. Rocha, P. Laguna. Are 2 ECG Leads Enough for Multilead Wave Boundary Location and QT Measuring?. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 593-596. Septiembre. 2009.

M. Orini, R. Bailón, L. Mainardi, A. Minchole, P. Laguna. Continuous Quantification of Spectral Coherence Using Quadratic Time-Frequency Distributions: Error Analysis and Application. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 681-684. Septiembre. 2009.

D. Smith, K. Solem, P. Laguna, J. P. Martínez, L. Sörnmo. Heart Rate Turbulence Detection Using Mean Shape Information. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 153-156. Septiembre. 2009.

D. Romero, E. Pueyo, M. Ringborn, P. Laguna. QRS slopes for ischemia monitoring in PCI recording. Medical Physics and Biomedical Engineering World Congress. Septiembre. 2009.

J. P. Martínez, D. Smith, A. Bayes de Luna, P. Laguna, L. Sörnmo. Risk Stratification in Congestive Heart Failure Patients Using a Model-Based Approach to Heart Rate Turbulence Characterization. XXXVI Ann. Conf. Computers in Cardiology. Park City, pp. 337-340. Septiembre. 2009.

D. Romero, E. Pueyo, M. Ringborn, P. Laguna. Spatial Characterization of Ischemia in 12-lead ECG Recordings during PCI using both Depolarization and Repolarization Indices. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 113-116. Septiembre. 2009.

F. Simón, A. Arenal, P. Laguna, J. P. Martínez. Stability and Correlation of Electrogram Organization and Synchronization Indices during Atrial Fibrillation. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 681-684. Septiembre. 2009.

R. Correa, P.D. Arini, E. Laciar, P. Laguna, R. Jané. Study of Morphological Parameters of QRS Loop Using Singular Value Decomposition during Ischemia Induced by Coronary Angioplasty. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 693-696. Septiembre. 2009.

A. Mincholé, E. Pueyo, P. Laguna. Transmural Differences in Rate Adaptation of Repolarization Duration Quantified from ECG Repolarization Interval Dynamics. XXXVI Ann. Conf. Computers in Cardiology, Park City, pp. 597-600. Septiembre. 2009.

J. R. Bolea, R. A. Almeida, P. Laguna, L. Sörnmo, J. P. Martínez. BioSigBrowser, biosignal processing interface. 9th International Conference on Information Technology and Applications in Biomedicine. Noviembre. 2009.

J. R. Bolea Bolea, R. A. Almeida, P. Laguna, L. Sörnmo, J. P. Martínez. BioSigBrowser, interfaz de procesado de señales biomédicas. XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 541-544. Noviembre. 2009.

E. Gil, J.M. Vergara, P. Laguna Comparación entre la variabilidad del tiempo de tránsito del pulso y la variabilidad del ritmo cardiaco durante descensos en la amplitud de las fluctuaciones de la señal fotopletismográfica .XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 565-568. Noviembre. 2009.

A. Minchole, E. Pueyo, P. Laguna. Diferencias Transmurales en la adaptación a cambios del ritmo cardiaco medidas sobre el ECG. XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 597-600. Noviembre. 2009.

F. Simón, A. Arenal, P. Laguna, J. P. Martínez. Estabilidad y Correlación de Índices de Organización y Sincronización en Electrogramas durante Fibrilación Auricular .XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 609-612. Noviembre. 2009.

E. Cirugeda, M. Orini, R. Bailón, P. Laguna. Estimación de la Frecuencia Respiratoria Mediante Análisis Tiempo-Frecuencia de la Señal de Variabilidad del Ritmo Cardíaco" . XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 613-616. Noviembre. 2009.

M. Noriega, R. A. Almeida, J. P. Martínez , P. Laguna Medida Multiderivacional de QT en el ECG de 12 derivaciones del sistema EASI" .XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 625-628. Noviembre. 2009.

M. Orini, R. Bailón, A. Minchole, L. Mainardi, P. Laguna. Metodología para el seguimiento de las dinámicas cardiovasculares a través de la coherencia tiempo-frecuencia" .XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 629-632. Noviembre. 2009.

D. Romero, E. Pueyo, M. Ringborn, P. Laguna. Pendientes del QRS para la monitorización de isquemia en registros de intervención coronaria percutánea .XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica, pp. 433-436. Noviembre. 2009.

M. Llamedo, J. P. Martínez (2009). Clasificación de ECG basada en Características de Escala, Dirección y Ritmo. XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica.

V. Monasterio, J. P. Martínez (2009). Comparación de Técnicas Multiderivacionales para Detectar Alternancias de Onda T en el ECG.XXVII Congreso Anual de la Sociedad española de Ingeniería Biomédica (CASEIB09). pp.99-102.

Ph.D. Thesis

Gil E. (2009). Análisis multimodal de las señales fotopletismográfica de pulso y electrocardiográfica para el diagnóstico del síndrome de apnea obstructiva durante el sueño en niños. Zaragoza university

Gouveia S. (2009). Contributions to the analysis of short term cardiovascular coupling. Porto University

2008

Journals and Books

M. Mendez, A. M. Bianchi, N. Montano, V. Patruno, E. Gil, C Mantaras, S Aiolfi, S. Cerutti (2008). On arousal from sleep: time-frequency analysis. Medical Biological Engineering Computing, vol. 46, pp. 341-351

Pueyo E., Sörnmo L., y Laguna P. (2008). QRS Slopes for Detection and Characterization
of Myocardial Ischemia. IEEE Trans. on Biomedical Engineering, vol. 55, n. 2, pp. 468-568. 10.1109/TBME.2007.902228

E. Pueyo, M. Malik, y P. Laguna P. (2008). A dynamic model to characterize beat-to-beat adaptation of repolarization to heart rate changes Biomedical signal processing and control, Elsevier., vol. 3 pp. 29-43; doi:10.1016/j.bspc.2007.09.005

P.D. Arini, G.C. Bertrán, E.R. Valverde, y P. Laguna P. (2008). T-wave Width as an Index for Quantification of Ventricular Repolarization Dispersion: Evaluation in an Isolated Rabbit Heart Model. Biomedical signal processing and control, Elsevier. vol. 3, pp. 67-77 doi:10.1016/j.bspc.2007.10.001

E. Gil, J.M. Vergara, P. Laguna (2008). Detection of decreases in the amplitude fluctuation of pulse photoplethysmography signal as indication of Obstructive Sleep Apnea Syndrome in children.Biomedical signal processing and control, Elsevier, doi:10.1016/j.bspc.2007.12.002.2008.

Solem K., P. Laguna Lasaosa, J. P. Martínez Cortes, L. Sörnmo (2008). Model-based Detection of Heart Rate Turbulence. IEEE Trans. on Biomedical Engineering, Vol. 55, n. 12, pp. 2712-2722 doi:10.1109/TBME.2008.2002113.

Conference Proceedings

V. Monasterio, J. P. Martínez (2008). Multilead Analysis of T Wave Alternans in Stress Tests".In Lectures Notes of the ICB Seminars, International Centre of Biocybernetics, Polish Academy of Science. Warsaw (Poland),

V Monasterio, JP Martínez (2008) Multilead T-Wave Alternans Quantification Based on Spatial Filtering and the Laplacian Likelihood Ratio Method, Computers in Cardiology, pp. 601-604 Bologna

M. O. Mendez, E. Gil, J. M. Vergara, S. Cerutti, A. M. Bianchi and P. Laguna (2008). Relationship among Envelope Fluctuations in PPG, HRV and apnea 25th Conference of the European Study Group on Cardiovascular Oscillations, (ESGCO08), Parma, CD. pp. P1B-24-27

E. Pueyo Paules, P. Laguna, B. Rodríguez (2008). Mechanisms of ventricular heart rate adaptation as an indicator of arrhythmic risk. Heart Rhythm, 29th Annual Scientific Sessions.

J. P. Martínez Cortes, P. Laguna, K. Solem, L. Sörnmo (2008). Evaluation of a Neyman-Pearson Heart-Rate Turbulence Detector. Proceedings of the 30th Annual International Conference of the IEEE EMBS, Vancouver August 20-24, 2008. pp 4407-4410.

E. Gil Herrando, M.O. Mendez, J.M. Vergara, S. Cerutti, A.M. Bianchi, P. Laguna (2008). Detection of Obstructive Sleep Apnea in children using decreases in the amplitude fluctuations of PPG signal and HRV. 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC08), Vancouver, CD. pp. 3479-3482.

M. Orini, B. F. Giraldo, R. Bailón, M. Vallverdú, L. Mainardi, S. Benito, I. Díaz P. Caminal (2008) Time-Frequency Analysis of Cardiac and Respiratory Parameters for the Prediction of Ventilator Weaning. 30th Annual International IEEE EMBS Conference Vancouver, British Columbia, Canada, pp.2793-2796.

V. Monasterio, P. Laguna, J. P. Martínez (2008). Multilead estimation of T-wave alternans in the ECG using principal component analysis. 16th European Signal Processing Conference (EUSIPCO 2008). Lausanne, Switzerland. CD.

E. Pueyo, P. Laguna, B. Rodriguez (2008). Short-term cardiac memory and arrhythmogenesis. 32nd Meeting of the European Working Group on Cardiac Cellular Electrophysiology.

R. Almeida, J. P. Martínez, A. P. Rocha, P. Laguna (2008). QRS complex boundaries location for multilead electrocardiogram. Compstat 2008. Porto.

P. Rivera, P. Laguna , J. P. Martínez , J. Pérez Turiel, A. Herreros, S. Wong (2008) . An Alternative Decision Rule for Threshold Based T-Wave Measurement Algorithms Based on Second Derivative Extrema. Computers in Cardiology, pp. 709-712. Bologna.

S. Gouveia, A.P. Rocha, P. Laguna, M. Gujic, S.P. Beloka, P. Van de Borne, P. Lago (2008). BRS Analysis from Baroreflex Sequences and Baroreflex Events Compared Using Spontaneous and Drug Induced Data. Computers in Cardiology. pp. 737-740.. Bologna.

P. D. Arini, F. H. Baglivo, J. P. Martínez , P. Laguna (2008). Ventricular repolarization dispersion during ischemia course measured by temporal and spatial ECG parameters. Computers in Cardiology, pp. 323-326. Bologna.

E. Gil, M. Mendez, J. M. Vergara, S. Cerutti, A. M. Bianchi, P. Laguna (2008). Detección de Apnea del Sueño en niños mediante el Descenso en la Amplitud de las Oscilaciones de la Señal PPG y la HRV. XXVI Congreso Anual de la Sociedad española de Ingeniería Biomédica, Valladolid, pp. 513-516.

V. Monasterio, P. Laguna , J. P. Martínez (2008). Estimación Multiderivacional de Alternancias de Onda T con Análisis de Componentes Principales. Comunicaciones del XXVI Congreso Sociedad Española de Ingeniería Biomédica. pp. 41-44.

V. Monasterio, J. P. Martínez (2008) Análisis Multiderivacional de Alternancias de Onda T en Prueba de Esfuerzo".Comunicaciones del XXVI Congreso Sociedad Española de Ingeniería Biomédica. pp. 45-48. Octubre. 2008

2007

Journals and Books

J. P. Martínez, P. Laguna, S. Olmos Gasso, O. Pahlm, J. Pettersson, L. Sornmo (2007). "Evaluation of QT measurements based on standard 12-lead ECG vs EASI-derived ECG" Journal of Electrocoardiologvol.40, n.2, pp. 172-179.

Francisco Castells, Pablo Laguna, Leif Sörnmo, Andreas Bollmann, and José Millet Roig (2007), Principal Component Analysis in ECG Signal Processing, EURASIP Journal on Advances in Signal Processing, vol. 2007, Article ID 74580, 21 pages, 2007. doi:10.1155/2007/74580

Sandham W., D. Hamilton, P. Laguna and M. Cohen (2007). Editorial. Advances in Electrocardiogram Signal Processing and Analysis. EURASIP Journal of Applied signal processing, vol. 2007, Article ID 69169 , 5 pages, 2007. doi:10.1155/2007/69169

Pueyo E., Laciar E., Anzuola E., Laguna P. and Jané R. (2007). QRS slopes for assessment of myocardial damage in chronic chagasic patients. Journal of Physics: Conference Series 90. 012077 doi:10.1088/1742-6596/90/1/012077,

Conference Proceedings

M Llamedo, JP Martínez (2007) An ECG Classification Model based on Multilead
Wavelet Transform Features Computers in Cardiology, pp. 105-108. Septiembre. 2007

V Monasterio, JP Martínez (2007) A Multilead Approach to T-Wave Alternans
Detection Combining Principal Component Analysis and the Laplacian Likelihood Ratio Method Computers in Cardiology, pp. 5-8. Septiembre. 2007

Gil E., J. M. Vergara, A. Bianchi, P. Laguna (2007). Obstructive Sleep Apnea Syndrome analysis in children by Decreases in the Amplitude & Fluctuations of Pulse Photoplethysmography: role of recording duration and Heart Rate Variability. 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07), Lyon, CD. pp. 6089-6093.

Minchole A., F. Jager and P. Laguna (2007). Discrimination between Demand and Supply Ischemia Episodes in Holter Recordings . 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07), Lyon, CD. pp. 2579-2582.

Simon F., J. P. Martinez, P. Laguna, B. van Grinsven, C. Rutten, and R. Houben (2007). Impact of Sampling Rate Reduction on Automatic ECG Delineation . 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07), Lyon, CD. pp. 2587-2590.

Bailón R., P. Laguna, L. Mainardi and L. Sörnmo (2007). Analysis of Heart Rate Variability Using Time-Varying Frequency Bands Based on Respiratory Frequency . 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC07), Lyon, CD. pp. 6674-6677.

E. Pueyo Paules, E. laciar, E. Anzuola, P. Laguna Lasaosa, R. Jané. Pendientes del QRS para la evaluación del daño miocárdico en pacientes chagásicos crónicos. Comunicaciones del XVI Congreso Sociedad Argentina de Bioingeniería, San Juan, Argentina. pp. 543-546. Septiembre. 2007.

E. Pueyo Paules, E. Anzuola, E. Laciar, P. Laguna Lasaosa, R. jane. " Assessment of Myocardial Damage in Chronic Chagasic Patients using QRS Slopes" .Computers in Cardiology, pp. 725-728 . Septiembre. 2007.

C. Maier, V. Rödler, P. Laguna Lasaosa, H. Dickhaus. " Dynamic Analysis of ECG Inter-Lead Transfer Properties for Detection and Categorization of Respiratory Events during Sleep" .Computers in Cardiology, pp. 493-496. Septiembre. 2007.

S. Gouveia, A.P. Rocha, P. Laguna Lasaosa, P. lago. " Improved Time Domain BRS Assessment with the Use of Baroreflex Events" .Computers in Cardiology, pp. 813-816. Septiembre. 2007.

M. Orini, R. Bailón Luesma, P. Laguna Lasaosa, L. Mainardi. " Modeling and Estimation of Time-Varying Heart Rate Variability during Stress Test by Parametric and Non Parametric Analysis" .computers in cardiology, pp. 29-32. Septiembre. 2007.

K. Solem, P. Laguna Lasaosa, J. P. Martínez Cortes, L. Sörnmo. " Performance Evaluation of Heart Rate Turbulence Detection Using an Extended IPFM Model" .Computers in Cardiology, pp. 821-824. Septiembre. 2007.

F. Simón Vadillo, P. Laguna Lasaosa, E. Pueyo Paules. " Study of the Dynamic Relationship between T Wave Morphology and Heart Rate during Ischemia" .Computers in Cardiology, pp 297-300. Septiembre. 2007.

S. Gouveia, A.P. Rocha, P. Laguna Lasaosa, P. Lago. " Thresholds Sensitivity in Time Domain BRS Estimation: Minimum Beat-to-Beat Changes and Minimum Correlation" .Computers in Cardiology, pp. 557-560. Septiembre. 2007.

R. Almeida, A. P. Rocha, J. P. Martínez Cortes, P. Laguna Lasaosa. "Quantification of variability interactions in multilead ECG: applicability as function of variability and noise levels" .56th Session of the International Statistical Institute (ISI 2007). Lisboa. . Agosto. 2007.

E. Pueyo, M. Malik, P. Laguna . "Dynamic Repolarization Assessment and Arrhythmic Risk Stratification".11th Mediterranean Conference on Medical and Biomedical Engineering and Computing 2007, pp. 74-77. doi: 10.1007/978-3-540-73044-6. 2007.

E. Gil Herrando, J.M. Vergara, P. Lagun. Análisis del Síndrome de Apnea Obstructiva en niños mediante el Descenso en la Amplitud de oscilación de la señal Fotopletismográfica de Pulso: estudio del efecto de la duración de los registros y la Variabilidad de Ritmo Cardíaco.XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica, Cartagena, Noviembre, pp. 36-39. Noviembre. 2007.

M. Orini, R. Bailón , P. Laguna , R. Enk, S. Koelsch. Análisis Tiempo Frecuencia de la Influencia de la Música sobre la Variabilidad Del Ritmo Cardiaco. XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica, Cartagena, noviembre, pp 278-281. Noviembre. 2007.

A. Mincholé , P. Laguna. Discriminación entre isquemia de demanda y de suministro en registros Holter. XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica, Cartagena, noviembre, pp. 326-329. Noviembre. 2007.

P. Rivera, J. Perez Turiel, S. Wong, P. Laguna , A. Herreros. Diseño y validación de un metodo basado en wavelets para deteccion del final de la onda T. XXV Congreso Anual de la Sociedad española de Ingeniería Biomédica, Cartagena, noviembre, pp. 310-313. Noviembre. 2007.

F. Simón , J. P. Martínez, P. Laguna , R. Houben, B. van Grinsven, C. Rutten. Impacto de la reducción de la frecuencia de muestreo en la delineación automática de ECG. XXV Congreso Anual de la Sociedad Española de Ingeniería Biomédica pp. 172-175. Noviembre. 2007.

M. Llamedo, J. P. Martínez (2007). An ECG Classification Model based on Multilead Wavelet Transform Features XVI Congreso Argentino de Bioingeniería, San Juan. pp 531-534.

V. Monasterio, J. P. Martínez (2007).Un detector multiderivacional de alternancias de onda T basado en análisis de componentes principales".XXV Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB 07). pp. 32-35.

Ph.D. Thesis

Arini P. (2007). Estudio y cuantificación de la dispersión de la repolarización ventricular cardiaca a través de la onda T en la se˜nal electrocardiográfica , Zaragoza University.

2006

Journals and Books

L. Sörnmo, P. Laguna (2006). Electrocardiogram (ECG) Signal Processing. in Wiley Encyclopedia of Biomedical Engineering, Metin Akay (Editor), Volume 2, pages 1298-1313. (2006) Wiley. ISBN: 0-471-24967-X (CL).

R. Bailón, L. Sörnmo, P. Laguna (2006). ECG-derived respiratory frequency estimation. In F. Azuaje GD. Clifford and PE. McSharry, editors, Advanced methods and tools for ECG data analysis. pp. 215 -- 244. Artech House, Inc.

R. Bailón, L. Sornmo, P. Laguna (2006). A robust method for ECG-based estimation of the respiratory frequency during stress testing. IEEE Transactions on Biomedical Engineering, vol. 53, n.7, pp. 1273-1285.

K. Solem, P. Laguna, L. Sörnmo (2006). An Efficient Method for Handling Ectopic Beats Using The Heart Timing Signal. IEEE Transaction on Biomedical Engineering, vol. 53, n. 1. pp. 13-20.

J. P. Martínez, S. Olmos, G. Wagner, P. Laguna (2006). Characterization of repolarization alternans during ischemia: time-course and spatial analysis. IEEE Transactions on Biomedical Engineering. vol. 53, n. 4, pp.701-711.

R. Almeida, S. Gouveia, A. P. Rocha, E. Pueyo, J. P. Martínez, P. Laguna (2006). QT variability and HRV interactions in ECG: Quantification and Reliability. IEEE Trans. on Biomedical Engineering, vol. 53, n.7, pp. 1317-1329.

Conference Proceedings

Gil E., J. M. Vergara, P. Laguna (2006). Study of the relationship between Pulse Photopletismography amplitude decrease events and sleep apneas in children. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC06), New York, CD. pp. 3887-3890

Martínez J.P., P. Laguna, S. Olmos, O. Pahlm, J. Petersson and L. Sörnmo (2006). Accuracy of QT Measurement in the EASI-derived 12-lead ECG, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC06), New York, CD. pp. 3986-3989.

K. Solem, P. Laguna Lasaosa, L. Sörnmo. Detection of Heart Rate Turbulence Using an Extended IPFM Model .Computers in Cardiology 2006. Accepted. 2006. pp. 905-908.

E. Gil Herrando, MO Mendez,, O Villantieri,, JM Vergara,, AM Bianchi,, P. Laguna Lasaosa. Heart Rate Variability during Pulse Photoplethismography Decreased Amplitude Fluctuations and Its Correlation with Apneic Episodes .Computers in Cardiology . 2006. pp. 165-168.

S Gouveia*,, AP Rocha,, P. Laguna Lasaosa, P Van de Borne,, P Lago. Improved BRS Assessment Using the Global Approach in the Sequences Technique .Computers in Cardiology 2006. pp. 641-644.

R. Bailón Luesma, L. Mainardi, P. Laguna Lasaosa. Time-Frequency Analysis of Heart Rate Variability during Stress Testing Using “a Priori” Information of Respiratory Frequency .Computers in Cardiology, 2006. pp. 169-172.

M Llamedo Soria, J. P. Martínez Cortes, P. Laguna Lasaosa. A Multilead Wavelet-Based ECG Delineator Based on the RMS Signal .Computers in Cardiology 2006. Septiembre. 2006. pp. 153-156.

P. Arini, J. P. Martínez Cortes, P. Laguna Lasaosa. Analysis of T-Wave Width during Severe Ischemia Generated by Percutaneous Transluminal Coronary Angioplasty .Computers in Cardiology 2006. . Septiembre. 2006. pp. 713-716.

R. Almeida, J. P. Martínez Cortes, A. P. Rocha, S. Olmos Gasso, P. Laguna Lasaosa. Automatic Multilead VCG Based Approach for QT Interval Measurement .Computers in Cardiology 2006. Septiembre. 2006. pp. 369-372

J. P. Martínez Cortes, R. Almeida, S. Olmos Gasso, A. P. Rocha, P. Laguna Lasaosa. Stability of QT Measurements in the PTB Database Depending on the Selected Lead .Computers in Cardiology 2006. Septiembre. 2006. pp. 341-344.

A. Mincholé Lapuente, J. P. Martínez Cortes, P. Arini, M. Risk, P. Laguna Lasaosa. T Wave Width Alterations during Valsalva Maneuvers in Diabetic Patients .Computers in Cardiology 2006. Septiembre. 2006. pp. 709-712

Aisa J., R. Bailón, P. Laguna. (2006) Análisis de las coherencias entre la variabilidad del ritmo cardiaco, la variabilidad de la presión sanguínea y la respiración" .XXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 37-40. Noviembre.

Mincholé A., J. P. Martínez, P. Arini, M. Risk, P. Laguna (2006) Cambios en la repolarización cardiaca generados por la maniobra de Valsalva y medidos sobre el ECG. XXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 29-32. Noviembre. 2006

Gil E., M.O. Mendez, O. Villantieri, J. Mateo, J.M. Vergara, A.M. Bianchi, P. Laguna. (2006). Relación entre la Variabilidad de Ritmo Cardiaco y las caídas en la amplitud de oscilación de la señal Fotopletismográfica de Pulso durante apneas en niños .XXIV Congreso Anual de la Sociedad Española de Ingeniería Biomédica. pp. 33-36, Noviembre. 2006

Ph.D. Thesis

Bailón R. (2006). Análisis de la señal electrocardiográfica durante prueba de esfuerzo y su aplicación en el diagnóstico de cardiopatías, Zaragoza University.

Pueyo E. (2006) Detección de heterogeneidades en la depolarización y repolarización cardiacas a partir del electrocardiograma como mejora en la predicción del riesgo frente a arritmias. Zaragoza University.

Almeida R. (2006). Automatic ECG characterization: Aplication to QT interval variability. University of Porto

2005

Journals and Books

L. Sörnmo, P. Laguna (2005). Biomedical Signal Processing in Cardiac & Neurological Applications .Academic Press, Elsevier.

P. Laguna, L. Sornmo (2005). Biomedical Signal Processing in Cardiac & Neurological Applications. Solutions Manual .Academic Press, Elsevier.

Martínez J.P., Olmos S (2005) Methodological principles of T wave alternans analysis: A unified framework. IEEE Transactions on Biomedical Engineering. Vol. 52, n. 4, pp. 599-613. April. 2005.

Conference Proceedings

Solem K., P. Laguna, L. Sörnmo (2005). Evaluation of an efficient method for handling ectopic beats in HRV .13th Nordic Baltic Conference. Biomedical Engineering and Medical Physics (NBC05), Umea, Sweden.. Junio. 2005.

Llamedo, P. Arini, M. Risk, P. Laguna (2005). Effect of QT Interval Correction during Autonomic Blockade in Combination with Changes in Posture .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 519-522. Septiembre. 2005.

Mincholé A., B. Skarp, P. Laguna (2005). Evaluation of a Root Mean Square Based Ischemia Detector on the LTST Database .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 853-856. Septiembre. 2005.

Arini P., E. Valverde, G. Beltran, P. Laguna(2005). Geometrical and Temporal ECG Features for Quantification of Increased Ventricular Repolarization Dispersion in an Experimental Heart Rabbit Model .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 89-92. Septiembre. 2005.

Pueyo E., A. Arcineaga, P. Laguna (2005). High-Frequency Signature of the QRS Complex across Ischemia in PTCA Recordings Quantified by the Downward Slope of the QRS Complex .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 659-662. Septiembre. 2005.

Almeida R., J. P. Martínez, A. P. Rocha, S. Olmos, P. Laguna (2005). Improved QT Variability Quantification by Multilead Automatic Delineation .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 503-506. Septiembre. 2005.

Maier C, H Dickhaus, P. Laguna (2005). Morphological Variability Extraction from Multi-Lead ECGs for Improvement of Sleep Apnea Recognition .XXXII Ann. Conf. Computers in Cardiology. Lyon. IEEE Press. pp. 355-358. Septiembre. 2005.

Pueyo E, M. Malik, P. Laguna (2005). "Beat-to-beat Adaptation of QT Interval to Heart Rate" .27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. (EMBS05), Shanghai, CD . Septiembre. 2005.

Gil E., V. Monasterio, J. M. Vergara, P. Laguna (2005). "Pulse Photopletismography Amplitude Decrease Detector for Sleep Apnea Evaluation in Children" .27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC05, Shanghai, CD. . Septiembre. 2005.

Gil E., V. Monasterio, J. M. Vergara, P. Laguna (2005). Detección de trastornos respiratorios del sueño en niños basado en la señal fotopletismográfica de pulso .XX Symposium de la Unión Internacional de Radio (URSI). Gandia . Septiembre. 2005.

Llamedo M., P. Arini, M. Risk, P. Laguna (2005). Evaluación de la corrección del intervalo QT durante bloqueo del sistema nervioso autónomo y cambios posturales .XV Congreso Argentino de Bioingeniería, Parana, pp 1-4. Septiembre. 2005.

Silvester A., R. Bailón, P. Laguna, J. Mateo, P. Serrano (2005). Coherencia entre la frecuencia respiratoria y la variabilidad del ritmo cardiaco durante prueba de esfuerzo. XXIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 23-26, Noviembre. 2005.

Gil E., V. Monasterio, J.M. Vergara, P. Laguna (2005). Estudio de la relación entre los periodos de atenuación de la señal fotopletismográfica de pulso en niños y la apnea del sueño XXIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 113-116, Noviembre. 2005.

Mincholé A., B. Skarp, F. Jager, P. Laguna. (2005). Evaluación de un detector de isquemia basado en la raíz cuadrática media sobre la base de datos LTST con cancelación de cambios posturales . XXIII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 121-124, Noviembre. 2005.

Ph.D. Thesis

Martinez J.P. (2005). Analísis de alternancias de onda T en la señal electrocardiografica, Zaragoza University.

2004

Journals

Martínez J. P., Almeida R., Olmos S., Rocha A. P., y Laguna P. (2004). A Wavelet-Based ECG Delineator: Evaluation on Standard Database. IEEE Trans. on Biomedical Engineering, vol. 51, n. 4, pp. 570-581.

Pueyo E., García J., Wagner G., Bailón R., Sörnmo L. y Laguna P. (2004). Time course of ECG Depolarization and Repolarization changes during Ischemia in PTCA recordings. Methods Inf. Med., vol. 43, pp. 43-46.

Pueyo E., P. Smetana, P. Caminal, A. Bayes de Luna, M. Malik y P. Laguna (2004). Characterization of QT Interval Adaptation to RR Interval Changes and Its Use as a Risk-Stratifier of Arrhythmic Mortality in Amiodarone-Treated Survivors of Acute Myocardial Infarction IEEE Trans. on Biomedical Engineering, vol. 51, n. 9, pp. 1511-1520.

P. Smetana, E. Pueyo, Hnatkova K., Batchvarov V., Laguna P., y Malik M. (2004). Individual patterns of dynamic QT/RR relationship in survivors of acute myocardial infarction and their relationship to antiarrhythmic efficacy of amiodarone. Journal of Cardiovascular Electrophysiology., vol. 15, n.10, pp. 1147-1154.

Pueyo E., P. Smetana, P. Laguna y M. Malik (2004). Assessment of individual QT/RR relationship and hysteresis in post-infarction patients Italian Heart Journal, vol. 5, Suppleemnt n.1, pp. 165S-168S.

P. Smetana, E. Pueyo, K. Hnatkova, M. Malik. Circadian patterns of QTc Interval’. Chapter of the book 'Dynamic Electrocardiography'. Blackwell Futura Publishing. Editores: M. Malik y A. J. Camm. 2004.

Conference Proceedings

P. Laguna & L. Sörnmo, (2004). Modelling Heart Rate Variability. Sixteenth International Symposium on Mathematical Theory of Networks and Systems (MTNS2004), Loeven, CD-ROM Proceedings. Invited lecture.

K. Solem, P. Laguna & L. Sörnmo, (2004). Handling Of Ectopic Beats In Heart Rate Variability Analysis Using The Heart Timing Signal. Xth Mediterranean Conference on Medical and Biological Engineering. (MEDICOM2004), Ischia, CD proceedings.

P.D. Arini, E.R. Valverde, G.C. Bertrán, y P Laguna, (2004). Quantification of Ventricular Repolarization Dispersion on the ECG by the T Wave Duration XXXI International Conference on Computers in Cardiology IEEE Computer Society, Chicago, pp. 757-760.

Almeida, E. Pueyo, J.P. Martínez, A.P. Rocha y P Laguna, (2004). Quantification of the QT Variability Related to HRV: Robustness Study Facing Automat Delineation and Noise on the ECG. XXXI International Conference on Computers in Cardiology IEEE Computer Society, Chicago, pp. 769-772.

Bailón, O Pahlm, L Sörnmo, y P Laguna, (2004). Robust ECG Derived Respiration from Stress Test Recordings: Validation with Respiration Recordings. XXXI International Conference on Computers in Cardiology IEEE Computer Society, Chicago, pp. 293-296.

R. Almeida, A. P. Rocha, E. Pueyo,, J. P. Martínez Cortes, y P Laguna, (2004). Modelling short term variability interactions in ECG: QT versus RR .COMPSTAT'2004 Symposium. 23-27 August 2004. Prague (Czech Republic), pp 597-604. ISBN 3-7908-1554-3 Physica-Verlag Heidelberg New York.. Agosto. 2004.

R. Almeida, J. P. Martínez Cortes, A. P. Rocha, P. Laguna. S. Olmos. ECG automatic delineation using a wavelet-based multiscale approach .Mathematics in Signal Processing VI. Institute of mathematics and its applications (IMA). Cirencester. Accepted.. Diciembre. 2004.

J. P. Martínez Cortes, S. Olmos Gasso, G. Wagner, P. Laguna. Caracterización espacio-temporal del desplazamiento de ST y las alternancias de onda T en el ECG durante isquemia aguda de miocardio .XXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, pp. 203-206. Noviembre. 2004.

E. Gil , D. Lopez, J. M. vergara, P. Laguna. Detección de microdespertares durante el sueño a partir de la señal fotoplestimográfica . XXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Santiago de Compostela, pp. 207-210. Noviembre. 2004.

Mates C., Martínez J. P., Olmos S. Análisis de la repolarización ventricular en prueba de esfuerzo mediante KLT con escalado temporal . XXII Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB'04). pp. 221-224. Santiago de Compostela. Noviembre 2004.

Martínez J.P., Olmos S. Detección de alternancias de onda T en ruido no estacionario. IV Jornades de Recerca en Enginyeria Biomèdica. Barcelona. Junio 2004

2003
Journals

Mateo J. y Laguna P. (2003). Analysis of Heart Rate Variability in the Presence of Ectopic Beats Using the Heart Timing Signal. IEEE Trans. on Biomedical Engineering, vol. 50, n. 3, pp. 334-343.

Aström M., García J., Laguna P., Pahlm O., y Sörnmo L. (2003). Detection of body position changes using the surface Electrocardiogram. Medical and Biological Engineering and Computing, vol. 41, n. 2, pp. 164-171.

Leanderson S., Laguna P. y Sörnmo L. (2003). Estimation of the respiratory frequency using spatial information in the VCG. Medical Engineering & Physics vol. 25, pp. 501–507.

García J., Astrom M., Mendive J., Laguna P. y Sörnmo L. (2003). ECG-based detection of body position changes in ischemia monitoring. IEEE Transactions on Biomedical Engineering, vol. 50 n. 6 , pp: 677 -685.

Bailón R., Mateo J., Olmos S., Serrano P., García J., del Río A., Ferreira I.J., y Laguna P. (2003). Coronary Artery Disease Diagnosis Based on Exercise ECG Indexes from Repolarization, Depolarization and Heart Rate Variability. Medical and Biological Engineering and Computing. vol. 41, pp. 561-571.

Pueyo E., Smetana P., Laguna, P., y Malik M.(2003) Estimation of the QT/RR hysteresis lag. Journal of Electrocardiology, Supplement, vol 36, n. 4, pp: 187-190.

P. Smetana, E. Pueyo, K. Hnatkova, V. Batchvarov, A. J. Camm, M. Malik. (2003) Effect of amiodarone on the descending limb of the T wave. American Journal of Cardiology, vol.92, pp. 742-746. 2003.

Conference Proceedings

Martínez J.P., Olmos S. Detection of T wave alternans in non-stationary noise: A GLRT Approach . 30th Ann. Conf. Computers in Cardiology. IEEE. pp. 161-164. Thessaloniki, Greece.

R. Almeida, E. Pueyo, J.P. Martínez,A.P. Rocha, P. Laguna and S. Olmos (2003). Quantification of short term QT variability versus heeart rate variability. 7th Portuguese Conference on Biomedical Engineering (BioEng’2003), Lisboa, CD proceedings.

R. Bailón, J. Mateo, S. Olmos, P. Serrano, J. García, A. del Río, I.J. Ferreira, P. Laguna (2003) Computer-aided diagnosis of coronary artery disease by means of Stress ECG. First international congress on computational bioengineering, Zaragoza pp. 219-224

R. Almeida, J. P. Martínez, S. Olmos, A.P. Rocha, P. Laguna (2003). Automatic delineation of Tand P waves using a wavelet-based Multiscale approach. First international congress on computational bioengineering, Zaragoza pp. 243-247

E. Pueyo, P Smetana, M Malik, P Laguna (2003). Evaluation of QT Interval Response to Marked RR Interval Changes Selected Automatically in Ambulatory Recordings. XXX International Conference on Computers in Cardiology, IEEE Computer Society, Tesalonica, pp. 157-160.

R. Almeida, E Pueyo, JP Martínez, AP Rocha, S Olmos, P Laguna (2003) A Parametric Model Approach for Quantification of Short Term QT Variability Uncorrelated with Heart Rate Variability XXX International Conference on Computers in Cardiology IEEE Computer Society, Tesalonica, pp. 165-168.

R. Bailón, S Olmos, M Horácek, P Laguna (2003) Identification of Patients at Risk for Ventricular Tachycardia by Means of Body Surface Potential Maps XXX International Conference on Computers in Cardiology IEEE Computer Society, Tesalonica, pp. 217-220.

R. Bailón, D Habas, L Sörnmo, P Laguna(2003). Robust Estimation of Respiratory Frequency from Exercise ECG Recordings XXX International Conference on Computers in Cardiology IEEE Computer Society, Tesalonica, pp. 299-302.

M. Canales, J Mateo, R Bailón, P Serrano, P Laguna (2003). Coherence between Heart Rate and Dominant Frequency of the Time-Frequency Heart Rate Variability Spectrum as Ischemic Marker in the Exercise Test. XXX International Conference on Computers in Cardiology IEEE Computer Society, Tesalonica, pp. 805-808.

R. Bailón, S. Olmos, M. Horacek y P. Laguna (2003) The use of body surface potential mapping in the identification of risk for ventricular tachycardia. In Lectures Notes of the ICB Seminars, International Centre of Biocybernetics, Polish Academy of Science. Warsaw (Poland), 2003. pp. 39-45

P. D. Arini, G. C. Bertrán, E. R. Valverde, M. O. Biagetti, R. A. Quinteiro, and P. Laguna (2003). Análisis de la morfologíia de la onda T durante incrementos en la dispersión de la repolarización ventricular. XXI Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Merida, pp. 93-96.

R. Bailón, D. Habas, L. Sörnmo, and P. Laguna (2003). Estimación robusta de la frecuencia respiratoria a partir del ecg registrado durante prueba de esfuerzo. XXI Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Merida, pp. 283-286.

2002

Journals

P. Laguna. (2002). Synopsis on signal processing papers of the yearbook on medical informatics. Guess editor and invited synopsis, Yearbook of Medical Informatics 02, IMIA. Schattauer Publishing Company, Stuttgart. pp. 427-430.

S. Olmos, L. Sörnmo and P. Laguna (2002). Block adaptive filters with deterministic reference inputs for event related signals: BLMS and BRLS. IEEE Trans. on Signal Proc., vol. 50. n. 5, pp. 1102-1112

J. García, I. Martínez, L. Sörnmo, S. Olmos, A. Mur, and P. Laguna (2002). Remote Processing Server for ECG-Based Clinical Diagnosis Support. IEEE Trans. on Information Technology, vol. 6. n. 4, pp. 277-284

Conference Proceedings

R. Bailón, S. Olmos, , P. Serrano, J. García, y P Laguna (2002). Robust Measure of ST/HR Hysteresis in Stress Test ECG Recordings. XXIX International Conference on Computers in Cardiology IEEE Computer Society, Memphis, pp. 329-332.

Martínez J.P., Olmos S (2002). A robust T-wave alternans detector based on the GLRT for Laplacian noise distribution. Computers in Cardiology. IEEE Computer Society Press. pp.677-680. Memphis.

Olmos S., Martínez J.P., Sörnmo, L. (2002) Spatio-temporal linear expansions for repolarization analysis. Computers in Cardiology. IEEE Computer Society Press. pp. 689-692. Memphis.

Olmos S., Martínez J.P., Sörnmo, L. Subspace Detector for Multichannel Signals. XI European Signal Processing Conference. pp. 645-648. Toulouse, September, 2002.

E. Pueyo, P. Smetana, K. Hnatkoval, P. Laguna and M. Malik (2002). Time for QT Adaptation to RR Changes and Relation to Arrhythmic Mortality Reduction in Amiodarone-treated Patients. XXIX International Conference on Computers in Cardiology IEEE Computer Society, Memphis, pp. 565-568.

J.P. Martinez, S. Olmos and P. Laguna (2002). T Wave Alternans and Acute Ischemia in Patients Undergoing Angioplasty XXIX International Conference on Computers in Cardiology IEEE Computer Society, Memphis, pp. 569-572.

E. Pueyo, J. Gacía, G. Wagner, R. Bailón, L. Sörnmo y P. Laguna (2002). Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings. 4th Biosignal interpretation international workshop, IEEE Computer Society, Como, pp. 115-118.

J.M. Ferrero, P. Vera, L. Roa, F. del Pozo, P. Caminal, P. Laguna y E. Gomez (2002). Título de Ingenieria Biomedica. XX Congreso anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 429-434.

M. Canales, J. Mateo, R.Bailón, P. Serrano, y P. Laguna (2002). Valor clínico de la variabilidad del ritmo cardiaco como marcador de isquemia en la prueba de esfuerzo. XX Congreso anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 337-340.

R. Bailón, S. Olmos, , P. Serrano, J. García, y P. Laguna (2002). Obtención robusta de la histeresis del ST/HR en registros ECG de prueba de esfuerzo. XX Congreso anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 77-80.

E. Pueyo, P. Smetana, H. Knatkoval, M. Malik and P. Laguna (2002). Tiempo de adaptación del QT a cambios en el RR, relación con el riesgo de muerte arritmica. XX Congreso anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 73-76.

J.P. Martinez, S. Olmos and P. Laguna (2002). Alternancias de onda T e isquemia aguda en pacientes sometidos a angioplastía coronaria. XX Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 85-88.

A. Alesanco, J.R. Gallego, M. Canales, A. Valdovinos, P. Laguna and J. García (2002). Análisis de los errores producidos durante la transmisión de ECGs por un canal UMTS. XX Congreso Anual de la Sociedad Española de Ingeniería Biomédica, Zaragoza, pp. 85-88.

Martínez J.P., Olmos S. Detección robusta de alternancias de onda T basada en el GLRT para ruido laplaciano (in Spanish). XX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB'02). pp. 85-88. Zaragoza. Noviembre, 2002.

Olmos S., Martínez J.P., Sörnmo, L. Detectores mediante subespacios para señales multicanal (in Spanish). XX Congreso Anual de la Sociedad Española de Ingeniería Biomédica (CASEIB'02). pp. 353-356. Zaragoza. Noviembre, 2002.

2001

Journals

J. García, G. Wagner, L. Sörnmo, P. Lander and P. Laguna. (2001). Identification of the occluded artery in patients with myocardial ischemia induced by prolonged ptca using traditional vs. transformed ECG-based indexes. Selected paper from Computers and Biomedical Research Vol. 32 No. 5 Oct. pp. 470-482. in the Yearbook of Medical Informatics 01, section 4: Image and signal processing, IMIA. Schattauer Publishing Company, Stuttgart. pp. 401-413.

Sörnmo L., M. Aström, E. Carro, M. Stridh, y P. Laguna (2001). Nonlinear estimation of respiratory-induced heart movements and its application in ECG/VCG signal processing. Nonlinear Biomedical Signal Processing; Vol. II, Dynamic analysis and modeling; IEEE Press series on biomedical engineering, Metin Akay series editor. pp. 228-245.

Conference Proceedings

Martínez J.P., S. Olmos. y P. Laguna (2001). Evaluación de métodos de detección dinámica de alternancias de onda T. Estudio basado en un simulador. XVI Symposium nacional de la unión cientifíca internacional de radio (URSI), Madrid, Septiembre 2001.(CD-ROM) pp. 75-76.

Bailón R., J. Mateo, P. Serrano, S. Olmos, J. García, A. del Río, I. J. Ferreira y P. Laguna (2001), Índices clínicos durante la prueba de esfuerzo basados en el ECG: repolarización, depolarización y variabilidad del ritmo cardiaco. XVIV Congreso anual de la Sociedad Española de Ingeniería Biomédica, Madrid, pp. 141-144

Martínez I., L. Sörnmo, S. Olmos, A. Mur, R. Bailón, P. Laguna, y J. García (2001)Procesado remoto de señales ECG vía web XVIV Congreso anual de la Sociedad Española de Ingeniería Biomédica, Madrid. pp. 53-56.

García J., I. Martínez, L. Sörnmo, S. Olmos, A. Mur, y P Laguna Remote ECG-based Diagnosis Support Via Web. 5th World Multiconference on Systemics Cybernetics and Informatics (SCI 2001) and the 7th International Conference on Information Systems Analysis and Synthesis (ISAS 2001) International Institute of Informatics and Systemics, IEEE Computer Society Orlando, Vol I Information systems Development. pp. 383-387 Selected as best paper of the sesion.

Mateo J., P. Serrano, R. Bailón, J. García, A. Ferreira, A. Del Río, I.J. Ferreira, y P Laguna (2001) Heart Rate Variability Measurements during Exercise Test May Improve the Diagnosis of Ischemic Heart Disease, 23th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc. Estambul, CD-ROM.

Olmos S., L. Sörnmo, y P Laguna (2001) Block LMS Adaptive Filter with Deterministic Reference Inputs for Event-Related Signals, 23th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc. Estambul, CD-ROM.

Mateo J., P. Serrano, R. Bailón, S. Olmos, J. García, A. Del Río, I.J. Ferreira, y P Laguna (2001) ECG-Based clinical indexes during stress test including repolarization, depolarization and HRV. XXVIII International Conference on Computers in Cardiology IEEE Computer Society Rotherdam, pp. 309-312.

2000
Journals

García J., Wagner G., Sörnmo L., Olmos S., Lander P. y P. Laguna (2000). Temporal evolution of traditional versus transformed ECG-based indexes in patients with induced myocardial ischemia. Journal of Electrocardiology, vol. 33, n. 1. pp. 37-47.

Astrom M., Carro E., Sörnmo L., Laguna P., y Wohlfart B. (2000). Vectocardigraphic loop alignment and the measurement of morphologic beat-to-beat variability in noisy signal. IEEE Trans. on Biomedical Engineering, vol. 47, n. 4, pp. 497-506.

Mateo J. y Laguna P. (2000). Improved heart rate variability signal analysis from the beat occurrence times according to the IPFM model. IEEE Trans. on Biomedical Engineering, vol. 47, n. 8, pp. 985-996.

Olmos S., y P. Laguna (2000). Steady-satte MSE Convergence of LMS Adaptive Filters with Deterministic Reference Inputs, with applications to Biomedical Signals. IEEE Trans. on Signal Proceesing, vol. 48, n. 8, pp. 2229-2241.

Laguna P. y L. Sörnmo (2000). Sampling Rate and the Estimation of Ensemble Variability for Repetitive Signals. Medical and Biological Engineering and Computing, vol. 38, n. 5, pp. 540-546.

García J., Sörnmo L., Olmos S. y Laguna P. (2000). Automatic deteccion of ST-T complex changes on the ECG using filtered RMS difference series: Application to ambulatory ischemia monitoring. IEEE Trans. on Biomedical Engineering, vol. 47, n. 9, pp. 1195-1201.

Conference Proceedings

Romero G. y P. Laguna. (2000).Filtrado de Wiener en el plano tiempo-frecuencia aplicado a la electrocardiografía de alta resolución XV Symposium nacional de la unión cientifíca internacional de radio (URSI), Zaragoza. Septiembre (CD-ROM).

Martínez I., J. García, Sörnmo L. y P. Laguna. (2000).Servidor centralizado de acceso remoto para obtención de información clínica sobre el ECG. XV Symposium nacional de la unión cientifíca internacional de radio (URSI), Zaragoza (CD-ROM).

Mateo J. y P. Laguna. (2000). Análisis espectral de la variabilidad del ritmo cardiaco mediante la señal temporización cardiaca. TELEC'2000 Sociedad Cubana de Telecomunicaciones Cuba, Proc. TELEC'2000, Santiago de Cuba. ISBN:84-8138-393-7.

Laguna P., L. Sörnmo y S. Olmos (2000). Adaptive Estimation of Evoked Potentials: A Cycle-Stationary Perspective with the LMS Algorithm, 22th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Chicago, Scientific Session: WE-A328-04.

Martínez J. P., S. Olmos y P. Laguna (2000). Simulation Study and Performance Evaluation of T-Wave Alternans Detectors, 22th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Chicago, Scientific Session: TH-A206-03.

Martínez J. P., S. Olmos y P. Laguna (2000). Evaluation of a wavelet-based ECG waveform detector on the QT Database XXVII International Conference on Computers in Cardiology, IEEE Computer Society Boston, pp. 81-84.

Martínez J. P., S. Olmos y P. Laguna (2000). T wave alternans detection: A simulation study and analysis of the European ST-T Database XXVII International Conference on Computers in Cardiology IEEE Computer Society, Boston, pp. 155-158.

Mateo J. y P. Laguna (2000). Extension of the heart timing signal to the HRV analysis in the presence of ectopics beats XXVII International Conference on Computers in Cardiology, Boston, pp. 813-816.

García J., P. Serrano, R. Bailón, E. Gutierrez, J.A. Casasnovas, I. Ferreira y P. Laguna (2000). Comparison of ECG-based clinical indexes during stress test. XXVII International Conference on Computers in Cardiology, Boston, pp. 833-836.

Martínez J.P., Olmos S. Sistema de detección de puntos significativos de la señal ECG basado en la transformada wavelet (in Spanish). Libro de actas del XV Simposium nacional de la Unión Científica Internacional de Radio. pp. 603-604. Zaragoza, 2000.

1999
Journals

P. Laguna, G.B. Moody, J. García, A.L. Goldberger and R.G. Mark (1999). Analysis of the ST-T Complex Using The KL Transform: Adaptive Monitoring and Alternans Detection. Medical and Biological Engineering and Computing. Vol 37, pp. 175-189.

J. García, G. Wagner, L. Sörnmo, P. Lander and P. Laguna. (1999). Identification of the occluded artery in patients with myocardial ischemia induced by prolonged ptca using traditional vs. transformed ECG-based indexes. Computers and Biomedical Research Vol. 32 No. 5 Oct. pp. 470-482.

S. Olmos, J. García, R. Jané and P. Laguna. (1999). ECG signal compression plus noise filtering with truncated orthogonal expansions. Signal Processing Vol. 79, pp. 97-115.

Olmos S., García J., Jané y P. Laguna (1999). Truncated Orthogonal expansions of recurrent signals: equivalence to a periodic time-variant filter. IEEE Trans. on Signal Proceesing, vol. 47, n. 11, pp. 3164-3172.

Conference Proceedings

J. García and P. Laguna (1999). Automatic ischemia episodes detection on ECG recordings. 5th Conf. of the European Society for Engineering and Medicine. Barcelona.

M. Astrom, L. Sörnmo, J. García and P. Laguna (1999). Least Squares VCG Loop Alignment. 3rd Iational Workshop on Biosignal Interpretation. Chicago (USA).ntern

M. Astrom, J. García, P. Laguna and L. Sörnmo. (1999), ECG based detection of body position changes. 21th Annual International Conference, IEEE Engineering in medicine and Biology Society. Atlanta (USA).

J. García, M. Astrom. L. Sörnmo and P. Laguna. (1999). Sistema de Deteccion de Cambios Posturales Durante la Monitorizacion de ECGs Basado en la KLT. Comunicaciones del XIV Symposium nacional de la unión cientifíca internacional de radio (URSI) Santiago de Compostela.

Caminal P., M. Vallverdu, X. Viñolas, J.L. Alonso, R. Jané, P. Laguna, M.V. Pitzalis, P. Rizzon, W. Zareba, A. Bayés de Luna.(1999). New algorithm for QT dispersion analysis in XYZ-lead Holter Description and Validation, XXI Congress of the European society of Cardiology European Society of Cardiology, Barcelona, pp. 338

Olmos S. y Laguna P.(1999). A Clinical Distortion Index for ECG data compression performance evaluation. 5nd European Conf. on Eng. and Med. European Society for Engineering and Medicine (ESEM), Barcelona, pp. 381-382.

Olmos S., J. P. Martínez y P. Laguna (1999).Performance evaluation of a time-variant filter for ECG signals. 5nd European Conf. on Eng. and Med. European Society for Engineering and Medicine (ESEM), Barcelona, pp. 385-386.

Mateo J. y Laguna P. (1999).A comparison between Time Domain HRV signals. 5nd European Conf. on Eng. and Med. European Society for Engineering and Medicine (ESEM), Barcelona, pp. 365-366.

Olmos S. y P. Laguna. (1999).Multi-lead ECG Data compression with Orthogonal Expansions: KLT and Wavelet Packets. XXVI International Conference on Computers in Cardiology, IEEE Computer Society Hannover, pp. 539-542.

García J., Åström M., Laguna P. y L. Sörnmo.(1999). Detection of Body Position Changes on the Surface ECG. XXVI International Conference on Computers in Cardiology, IEEE Computer Society, Hannover, pp. 45-48.

Laguna P. (1999) Sampling rate and the estimation of HF-ECGH ensamble variability I STAFF studies symposium Siemens AB Heart, 1999 Presentación invitada

Ph.D. Thesis

Mateo J. (1999) Análisis de la variabilidad del ritmo cardiaco: representación temporal e índices clínicos. Zaragoza University

1998
Journals

Laguna P., G. B. Moody and R.G. Mark (1998). Power Spectra Density of Unevenly Sampled Data by Least-Square Analysis: Performance and Application to Heart Rate Signals. IEEE Trans. on Biomedical Engineering Vol. 45, No. 6. June. pp. 698-715

García J., P. Lander, L. Sörnmo, S. Olmos, G. Wagner and P. Laguna. (1998). Comparative Study of Local and Karhunen-Loeve--Based ST-T Indexes in Recordings from Human Subjects with Induced Myocardial Ischemia. Computers and Biomedical Research Vol. 31 No. 4 August. pp. 271-292.

Laguna P., J. García, I. Roncal, G. Wagner, P. Lander y R.G. Mark (1998). Model-based estimation of cardiovascular repolarization features: ischemia detection and PTCA monitoring. J. Medical Eng. and Technology, vol. 22, n. 2, pp. 64-72.

Conference Proceedings

S. Olmos, J. García R. Jané y P. Laguna (1998). Truncated Orthogonal Expansions of Recurrent Signals: Equivalence to a Periodic Time-Variant Filter. ICASSP, IEEE Signal Processing Society. Seattle.

García J., G. Wagner, L. Sörnmo, S. Olmos, P. Lander, and P. Laguna. (1998), Temporal Evolution of ECG-Based Indexes in Patients with Myocardial Ischemia Induced by Prolonged Balloon Occlusion . Computers in Cardiology, IEEE Computer Society Press. Cleveland.

García J., G. Wagner, L. Sörnmo, P. Lander, and P. Laguna. (1998), Multivariate Discriminant Analysis of ECG-Based Indexes to Identify the Occluded Artery in Patients Undergoing PTCA . 20th Annual International Conference, IEEE Engineering in medicine and Biology Society. Hong Kong.

Laguna P. and Sörnmo L.. (1998), Sampling Rate and Time Alignment in the Estimation of QRS Variability. 20th Annual International Conference, IEEE Engineering in medicine and Biology Society. Hong Kong.

J. García y P. Laguna (1998). Diseño y evaluación de un detector de isquemia basado en la transformada de Karhunen-Loeve. Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 123-126.

Royo M. y P. Laguna (1998). Cancelación de variaciones d ela línea de base en el ECG: Estudio comparativo de diferentes técnicas.Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 135-138.

Blasi A., P. Caminal, M. Vallverdú, X. Viñolas, R. Jané, P. Laguna, y A. Bayés. (1998). Algoritmo para el análisis de la dispersión de QT en ECG Holter de 3 canales: validación y aplicaciones.Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 139-142.

Mañanas M. A., J. A. Fiz, J. Morera, P. Laguna, R. Jané y P. Caminal. (1998).Filtrado adaptativo de señales electromiográficas y vibromiograficas mediante el algoritmo LMS Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 185-188.

Ph.D. Thesis

Olmos S. (1998) Compresión de datos en señales ECG mediante transformadas ortogonales. Zaragoza Unievrsity/Universidad Politécnica de Cataluña,

Garcia J. (1998). Sistema de Monitorización y Detección de Isquemia Basado en la Transformada
de Karhunen-Loève Aplicada sobre el ECG. Zaragoza University.

1997
Journals

Homs E., V. Marti, J. Guindo, P. Laguna, X. Viñolas, P. Caminal, R. Elosua, y A. Bayes de Luna. (1997). Automatic measurement of corrected QT interval in Holter recordings: Comparison of its dynamic behavior in patients after myocardial infaction with and without life-threatening arrhythmias. American Heart Journal. Vol. 134.

Conference Proceedings

Olmos S., I. Rios, J. García, R. Jané y P. Laguna (1997), Scalar Quantizers for compression of ECG signal with orthogonal transforms. Computers in Cardiology, IEEE Computer Society Press. Lund.

Giraldo B., C. Farre, P. Laguna, R. Jané, M. Martin y P. Caminal (1997), Validation of an Algorithm for Atrial Fibrillation and Fluter Diagnosis. Computers in Cardiology, IEEE Computer Society Press. Lund.

Mateo J. y P. Laguna (1997), Improved Interpolation of Unevenly Sampled Heart Rate Signals. Computers in Cardiology, IEEE Computer Society Press. Lund.

Laguna P., R. G. Mark, A. Goldberg y G. B. Moody (1997), A Database for Evaluation of Algorithms for Measurement of QT and Other Waveform Intervals in the ECG. Computers in Cardiology, IEEE Computer Society Press. Lund.

Laguna P., B. Simon, y L. Sörnmo (1997), Improvement in High-resolution ECG Analysis by Interpolation Before Time Alignment. Computers in Cardiology, IEEE Computer Society Press. Lund.

Jané R., A. Blasi, J. García y P. Laguna (1997), Evaluation of an Automatic Threshold Based Detector of Waveform Limits in Holter ECG with the QT Database. Computers in Cardiology, IEEE Computer Society Press. Lund.

García J., I. Roncal and P. Laguna (1997), Myocardial ischemia detector based on Karhunen-Loève transform. World Congress on Medical Physics and Biomedical Engineering. Nice.

Olmos S., J. García y P. Laguna. (1997). Sistema de compresion de la señal ECG basado en la transformada de KL. Comunicaciones del XII Symposium nacional de la unión cientifíca internacional de radio (URSI) Bilbao. II/335-II/338.

García J., S. Olmos, L. Sörnmo, M. Ringborn, P. Lander, G. Wagner y P. Laguna. (1997). Estudio comparativo de Indices Clasicos y Basados en la KLT en Monitorizacion y Deteccion de Isquemia de Miocardio. Comunicaciones del XII Symposium nacional de la unión cientifíca internacional de radio (URSI) Bilbao. II/339-II/342.

Mateo J. y P. Laguna. (1997). La señal Heart Timing en el analisis de la variabilidad del ritmo cardiaco. Comunicaciones del XII Symposium nacional de la unión cientifíca internacional de radio (URSI) Bilbao. II/343-II/346

Olmos S., J. García, R. Jané y P. Laguna. (1997). Analisis de la señal ECG con expansiones ortogonales de reducido numero de coeficientes. Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 89-92.

Olmos S., D. Echeverria, R. Jané y P. Laguna (1997). Compresion de señales ECG multiderivacionales mediante expansiones ortogonales optimas: WP y KL Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 321-324.

Ibañez J y P. Laguna (1997). Determinacion de la relacion entre riesgo de muerte subita y correlacion del QT con el RR. Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 317-320.

Vullings E., J. García y P. Laguna (1997). Waveform detection in Holter ECG using dynamic time-warping. Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 313-316.

Carro E., M. Astrom, P. Laguna, B. Wohlfart y L. Sörnmo. (1997). Alineamiento de señales VCG: variabilidad morfologica de latido a latido en presencia de ruido. Comunicaciones del XV Congreso anual de la Sociedad Española de Ingenieria Biomedica (SEIB). Valencia. pp. 309-312.

1996
Journals

Laguna P., R. Jané, E. Masgrau and P. Caminal (1996). The Adaptive Linear Combiner with a Periodic-Impulse Reference Input as a Linear Comb Filter. Signal Processing Vol. 48, n. 3, pp. 193-203.

Laguna P., R. Jané, S. Olmso, N. Thakor, H. Rix and P. Caminal. (1996). Adaptive estimation of QRS complex by the Hermite model for classification and ectopic beat detection. Medical and Biological Engineering and Computing.vol. 34, pp. 58-68.

Conference Proceedings

Laguna P., M. Ruiz, G. Moody y R. Mark. (1996), Repolarization alternans detection using the KL transform andf the beatquency spectrum. Computers in Cardiology, IEEE Computer Society Press. Indianapolis.

Olmos S., M. Millan, J. García y P. Laguna. (1996), ECG data compression with the KL transform. Computers in Cardiology, IEEE Computer Society Press. Indianapolis.

Mateo J. y P. Laguna (1996), New heart rate variability time-domain signal construction from the beat Occurrence time and the IPFM model. Computers in Cardiology, IEEE Computer Society Press. Indianapolis.

García J., S. Olmos, G. Moody, R. Mark y P. Laguna (1996), Adaptive estimation of the KL series applied to the study of ischemic ECG records. Computers in Cardiology, IEEE Computer Society Press. Indianapolis.

Olmos S., R. Jané, J. García y P. Laguna (1996), Effects of noise in evaluating quality of reconstructed ECG signals from orthogonal transform data compression 18th Annual International Conference, IEEE Engineering in medicine and Biology Society. Amsterdam.

García J., S. Olmos, y P. Laguna (1996), Performance of RLS and LMS Algorithms in KL Estimation of Ischemic ECG Records 18th Annual International Conference, IEEE Engineering in medicine and Biology Society. Amsterdam.

Simon B., L. Sörnmo L. y P. Laguna (1996), Mejora en el alineamiento de registros ECG usando interpolación. Comunicaciones del XIV Congreso anual de la Sociedad Española de Ingeniería Biomédica. Pamplona. pp. 49-51.

Roncal I. y P. Laguna (1996), Detector de isquemia utilizando la transformada de Karhunen-Loève. Comunicaciones del XIV Congreso anual de la Sociedad Española de Ingeniería Biomédica. Pamplona. pp. 91-93.

García J., P. Lander, G. Wagner, S. Olmos y P. Laguna (1996), Analisis de la onda T como indicador sensible de isquemia cardiaca. Comunicaciones del XIV Congreso anual de la Sociedad Española de Ingeniería Biomédica. Pamplona. pp. 95-96.

Olmos S., y P. Laguna (1996). Efecto del ruido en la compresión de datos de la señal ECG mediante transformadas ortogonales. Comunicaciones del XI Symposium nacional de la unión cientifíca internacional de radio (URSI) Madrid. pp. 257-260.

1995
Journals

Laguna P., G. B. Moody, R. Jané, P. Caminal and R.G. Mark (1995). "The KL transform as a tool to analyze the ST segment: Comparison with QT interval". Journal of Electrocardiology vol. 28 (Suplement) pp. 41-49.

Conference Proceedings

Laguna P., Moody G.B. and Mark R.G.(1995). "Power Spectral Density of Unevenly Sampled Heart Rate Data" , Proc. of the 17th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc. Montreal. pp. 157-158.

Silipo R., Laguna P., Marchesi C. and Mark R.G.(1995). "ST-T Segment Change Recognition using Artificial Neural Networks and Principal Component Analysis". Computers in Cardiology, IEEE Computer Society Press, Viena, pp. 213-216

Giraldo B., Laguna P., Jané R. and Caminal P. (1995) "Automatic Detection of Atrial Fibrillation and Flutter Using Differentiated ECG Signal". Computers in Cardiology, IEEE Computer Society Press, Viena, pp. 369-372

Laguna P., G. B. Moody y R.G. Mark (1995). "PSD en Señales de Ritmo Cardiaco Muestreadas No Uniformemente" . XIII Congreso Anual de la Asociación Española de Bioingeniería. Barcelona. pp. 131-132.

Olmos S., Laguna P., Caminal P. y Jané R. (1995). "Compresión de Datos de la Señal ECG Mediante Transformadas Ortogonales" . XIII Congreso Anual de la Asociación Española de Bioingeniería. Barcelona. pp. 43-44.

García J., Lander P., Wagner G. y Laguna P. (1995), "Análisis de la Repolarización Cardiaca en el ECG, Registrado Durante Angioplastia, Mediante la Transformada de KL". XIII Congreso Anual de la Asociación Española de Bioingeniería. Barcelona. pp. 41-42.

1994

Journals

Laguna P., R. Jané y P. Caminal.(1994). "Automatic detection of wave boundaries in multilead ECG signals: Validation with the CSE database" . Computers and Biomedical Research, vol. 27, pp.45-60.

Laguna P., R. Jané y P. Caminal (1994). "A time delay estimator based on the signal integral: Theoretical perforoance and testing on ECG signals" . IEEE Trans. on Signal Processing vol. 42 nº11 pp. 3224- 3229

Conference Proceedings

Laguna P., G. B. Moody and R.G. Mark (1994). "Analysis of the Cardiac Repolarization Period Using the KL Transform: Aplications on the ST-T Database". Computers in Cardiology, IEEE Computer Society Press, Bethesda, pp. 233-236.

Lang E., Caminal P., Laguna P., Horváth G., Homs E., y Jané R. (1994). "Spectral components of heart rate variability (HRV) as markers to stratify risk following myocardial infarction (MI)" . Proc. of the V Int. Symposium on Biomedical Engineering. Santiago, Spain. pp. 57-58.

1993
Journals

N.V. Thakor, G. Xing-rong, P. Laguna, R. Jané, P. Caminal, y H. Rix (1992). "Orthonormal (Fourier and Walsh) models of time-varying evoked potentials in neurological injury". IEEE Trans. on Biomedical Engineering vol. 40, n.3 pp.213-221.

Conference Proceedings

Caminal P., Gomis P., Laguna P., y Jané R. (1993). "Application of parametric models to classify ECG signals". Proc. of thg 2nd European Conf. on Eng. and Med., Stuttgart, pp.354-355.

Jané R., Olmos S., Laguna P., y Caminal P. (1993). "ECG data compression using an adaptive hermite model" , Proc. of the 2nd European Conf.on Eng. and Med., Stuttgart, pp. 362-363.

Jané R., Olmos S. Laguna P., y Caminal P. (1993). "Adaptive Hermite models for ECG data compression: Performance and evaluation with automatic wave detection". Computers in Cardiology, IEEE Computer Society Press, Londres, pp. 389-392.

1992

Journals

Laguna P., R.Jané, O. Meste, P. Poon, P. Caminal, H. Rix, N.V. Thakor.(1992). "Adaptive filter for event-related bioelectric signals using an impulse correlated reference input: Comparison with signal averaging techniques". IEEE Trans. on Biomedical Engingering, vol. 39, n. 10. pp. 1032-1044

Conference Proceedings

Laguna P., Jané R., y Caminal P. (1992). "Adaptive feature extraction for QRS classification and ectopic beat detection using the Hermite functions", Computers in Cardiology, IEEE Computer Society, Venecia, pp. 613-616

Jané R., Laguna P. y Caminal P. (1992), "Filtering techniques for ventricular late potentials", Proc. of the 14th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Paris, pp. 545 - 546.

Laguna P., Jané R. y Caminal P.(1992), "Adaptive filtering of ECG baseline wander", Proc. of the 14th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Paris, pp. 508 - 509.

Laguna P., Vigo D., Jané R., y Caminal P. (1992). "Automatic waves onset and offset determination in ECG signals: Validation with the CSE database", Computers in Cardiology, IEEE Computer Society Press Durham.

Jané R., Laguna P., y Caminal P.(1992). "Adaptive baseline wander removal in the ECG: comparative analysis with cubic splines techniques, Computers in Cardiology", IEEE Computer Society Press, Durham.

1991

Journals

Jané R., H. Rix, P. Caminal y P. Laguna (1991). "Alignment methods for averaging of high resolution cardiac signals: a comparative study of performance". IEEE Trans. on Biomedical Engineering, vol. 34, n. 6, pp. 571-579.

Laguna P., P. Caminal, R. Jané y N.V. Thakor (1991). "Automatic QT interval analysis in postmyocardial infarction patients" . Journal of Ambulatory Monitoring. vol. 4, n. 2 . pp 91-111.

Conference Proceedings

Laguna P., Caminal P., Jané R., y Rix H. (1991). "Evaluation of HRV by PP and RR interval analysis using a new time delay estimate, Computers in Cardiology", IEEE Computer Society Press, Chicago, pp. 63- 66.

Jané R., Laguna P., Caminal P., y Rix H. (1991). " Adaptive filtering of high-resolution ECG signals".Computers in Cardiology, IEEE Computer Society Press, Chicago, pp. 347-350.

Laguna P., Rix H., Jané R. y Caminal P. (1991). "Estimation of signal-to-noise ratio in signals contamined by white noise", Proc. of the 13th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Orlando. pp. 363- 364.

Jané R., Laguna P. y Caminal P. (1991). "Adaptive estimation of event-related bioelectric sigoals: Effect of misalignment errors",Proc. of the 13th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Orlando. pp. 365- 366.

Thakor N.V., Vaz C., Xin-rong G., Poon P., Laguna P., Jané R., Caminal P. y Rix H. (1991), "Time- varying evoked potentials monitoring and signal processing", Proc. of the 13th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Orlando. pp. 415-416.

Jané R., Laguna P., Caminal P., Meste O., Rix H. y Thakor N.V. (1991). "Estimation of event-related bioelectric signals using adaptive filtering and everaging techniques", Proc. of the IV Int. Symposium on Biomedical Engineering., Peñiscola, Spain. pp. 316-317.

Laguna P., Bogatell E., Jané R. y Caminal P. (1991), "Automatic detection of characteristic points in the ECG", Proc. of the IV Int. Symposium on Biomedical Engineering, Peñiscola, Spain. pp. 338/339.

1990

Journals

Laguna P., N.V. Thakor, P. Caminal, R. Jané, H.R. Yoon (1990). "New algorithm for QT interval analysis in 24 hour Holter ECG: performance and applications". Medical and Biological Engineering and Computing, 28, pp. 67-73.

Laguna P., N.V. Thakor, P. Caminal, y R. Jané.(1990). "Low-pass differeotiators for biological signals with known spectra: application to ECG signal processing''. IEEE Trans. on Biomedical Engineering, vol. 37, n. 4, pp. 420-424.

Conference Proceedings

Laguna P., Rix H., Caminal P., y Jané R. (1990). "Performance analysis of a time delay estimate between two noisy transient signals". Proc. of the 12th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Philadelphia. pp. 877-878.

Jané R., Laguna P. y Caminal P. (1990). "Adaptive filtering of event-related bioelectric signals", Proc. of the 12th Int. Conf. of the IEEE Eng. in Med. and Biol. Soc., Philadelphia. pp. 864-865.

Ph.D. Thesis

Laguna P. (1990). Nuevas técnicas de procesado de señales electrocardiográficas: aplicación a registros de larga duración., Politecnique University of Catalunya / Zaragoza University.